Gene Information gene info

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GENE：MYH10

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MYH10
FullNmae myosin heavy chain 10
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7568
EnsembleID ENSG00000133026
Uniprot P35580

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MYH10 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MYH10 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MYH10 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MYH10 disulfidptosis 39948102 This study investigates the expression of disulfidptosis-related genes, particularly CD2AP and MYH10, in UC and COAD. retulator signature

Go Annotation:

GeneSymbol Go id
MYH10 GO:0000146,GO:0000146,GO:0000146,GO:0000281,GO:0000281,GO:0001725,GO:0003779,GO:0005515,GO:0005516,GO:0005524,GO:0005524,GO:0005634,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0005844,GO:0005938,GO:0007155,GO:0008360,GO:0016459,GO:0016460,GO:0016460,GO:0030027,GO:0030048,GO:0030496,GO:0031032,GO:0031032,GO:0032154,GO:0032982,GO:0035613,GO:0042641,GO:0043531,GO:0048027,GO:0050714,GO:0051015,GO:0051015,GO:0051015,GO:0070062,GO:0097513

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MYH10 hsa:4628 path:hsa04270 Vascular smooth muscle contraction - Homo sapiens (human)
MYH10 hsa:4628 path:hsa04530 Tight junction - Homo sapiens (human)
MYH10 hsa:4628 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
MYH10 hsa:4628 path:hsa04814 Motor proteins - Homo sapiens (human)
MYH10 hsa:4628 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MYH10 PBX1 12724421 23180781 physical association anti tag coimmunoprecipitation InnateDB
EED MYH10 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
MYH10 UBB 23180781 24816145 ubiquitination reaction ubiquitinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
GATA1 MYH10 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 MYH10 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXA1 MYH10 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 MYH10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MYH10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MYH10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MYH10 18971253 8931991 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MYH10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MYH10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MYH10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MYH10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MYH10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 MYH10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 MYH10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 MYH10 22395608 trascriptional regulation,stimulation inferred by curator TFlink
ATF1 MYH10 N/A trascriptional regulation,stimulation inferred by curator TFlink
CREB1 MYH10 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000600E6 MYH10 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A7F58 MYH10 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000017EA6A MYH10 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000F4AC3 MYH10 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001CC864 MYH10 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000008DA94 MYH10 24858044 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 MYH10 22135298 phosphorylation N/A PhosphoSite
PRKCZ MYH10 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
GOLGA2 MYH10 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PIK3R2 MYH10 25348397 N/A physical interaction ComPPI
LGALS3 MYH10 25348397 N/A physical interaction ComPPI
CDC42 MYH10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBASH3B MYH10 25348397 N/A physical interaction ComPPI
PAK2 MYH10 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A4 MYH10 25348397 N/A in vitro ComPPI
YWHAG MYH10 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
ZNF512B MYH10 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KEAP1 MYH10 25348397 N/A physical interaction ComPPI
CBL MYH10 25348397 N/A physical interaction ComPPI
SP1 MYH10 25348397 N/A physical interaction ComPPI
SHC1 MYH10 25348397 N/A physical interaction ComPPI
GRB2 MYH10 12577067 24234451 25348397 association pull down ComPPI,IntAct
JUN MYH10 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
COPS5 MYH10 18850735 24234451 25348397 association tandem affinity purification ComPPI,IntAct
NTRK1 MYH10 25348397 N/A physical interaction ComPPI
TRPM7 MYH10 18675813 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
APC MYH10 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
HSPA5 MYH10 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
RPA1 MYH10 25348397 N/A physical interaction ComPPI
PSMA1 MYH10 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
IKBKB MYH10 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TNFRSF1A MYH10 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PPP2CB MYH10 25348397 N/A physical interaction ComPPI
RALA MYH10 25348397 N/A physical interaction ComPPI
HNRNPL MYH10 25348397 N/A physical interaction ComPPI
IQGAP1 MYH10 25348397 N/A physical interaction ComPPI
CFTR MYH10 25348397 N/A physical interaction ComPPI
MARK4 MYH10 25348397 N/A physical interaction ComPPI
RELA MYH10 25348397 N/A tandem affinity purification ComPPI
GRK5 MYH10 25348397 N/A physical interaction ComPPI
RPA2 MYH10 25348397 N/A physical interaction ComPPI
RPA3 MYH10 25348397 N/A physical interaction ComPPI
ARRB2 MYH10 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2 MYH10 25348397 N/A physical interaction ComPPI
CUL1 MYH10 25348397 N/A physical interaction ComPPI
BCAP31 MYH10 25348397 N/A physical interaction,in vivo ComPPI
RAB11A MYH10 25348397 N/A physical interaction ComPPI
YWHAE MYH10 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FKBP3 MYH10 25348397 N/A physical interaction ComPPI
YAP1 MYH10 25348397 N/A physical interaction ComPPI
OCRL MYH10 24234451 25107275 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
HDAC6 MYH10 25348397 N/A physical interaction ComPPI
CHUK MYH10 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PTEN MYH10 25348397 N/A physical interaction ComPPI
RIPK2 MYH10 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK3 MYH10 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TNFRSF1B MYH10 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
VCAM1 MYH10 19738201 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
ITGA4 MYH10 25348397 N/A physical interaction ComPPI
EED MYH10 25348397 N/A physical interaction ComPPI
H3C1 MYH10 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SVIL MYH10 25348397 N/A in vitro,in vivo ComPPI
BECN1 MYH10 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TRIM25 MYH10 25348397 N/A physical interaction ComPPI
AMFR MYH10 25348397 N/A physical interaction ComPPI
BRCA1 MYH10 25348397 N/A physical interaction ComPPI
SSH1 MYH10 25348397 N/A physical interaction ComPPI
MAP3K3 MYH10 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PBX1 MYH10 12724421 25348397 27898060 N/A two hybrid,physical interaction,in vivo ComPPI,OmniPath
GNAI2 MYH10 25348397 N/A physical interaction ComPPI
TERF2 MYH10 25348397 N/A physical interaction ComPPI
MAGOH MYH10 25348397 N/A physical interaction ComPPI
FOXP1 MYH10 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
AURKAIP1 MYH10 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PRKAB1 MYH10 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SEPTIN7 MYH10 25348397 N/A physical interaction ComPPI
TNFRSF10D MYH10 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
IKBKE MYH10 14743216 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
HNRNPM MYH10 25348397 N/A physical interaction ComPPI
PAN2 MYH10 25348397 N/A physical interaction ComPPI
TRPM6 MYH10 18675813 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
EIF4A3 MYH10 25348397 N/A physical interaction ComPPI
MYH9 MYH10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,two hybrid,physical interaction,in vivo ComPPI,IntAct
MYO1C MYH10 25348397 N/A physical interaction ComPPI
ACTA2 MYH10 25348397 N/A physical interaction ComPPI
ILF3 MYH10 25348397 N/A physical interaction ComPPI
FUS MYH10 25348397 N/A physical interaction ComPPI
ALK MYH10 25348397 N/A physical interaction ComPPI
MCC MYH10 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MYL6 MYH10 25348397 N/A physical interaction ComPPI
MTMR8 MYH10 25348397 N/A physical interaction ComPPI
LLGL1 MYH10 24234451 25348397 27898060 7542763 physical association coimmunoprecipitation ComPPI,IntAct,OmniPath
MYH10 USP45 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYH10 SIRT7 25348397 N/A physical interaction ComPPI
MYH10 FBXO25 25348397 N/A physical interaction ComPPI
MYH10 ACTC1 25348397 N/A physical interaction ComPPI
MYH10 ESYT1 25348397 N/A physical interaction ComPPI
MYH10 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
MYH10 ASB12 25348397 N/A physical interaction ComPPI
MYH10 LGR4 25348397 N/A physical interaction ComPPI
MYH10 CAPZA2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYH10 MYO19 25348397 N/A physical interaction ComPPI
MYH10 MYL3 25348397 N/A physical interaction ComPPI
MYH10 IKBKG 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
MYH10 MAP3K1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
MYH10 EPB41 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MYH10 PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
COX4I1 MYH10 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ECPAS MYH10 25348397 N/A physical interaction ComPPI
DUX4 MYH10 24234451 25348397 26816005 association pull down ComPPI,IntAct
MYH10 MYH10 21078954 24234451 N/A cosedimentation in solution IntAct
MYH10 EFHD2 24234451 30021884 physical association cross-linking study IntAct
MYH10 IL1R1 24234451 30021884 physical association cross-linking study IntAct
MYH10 ATP6V1B1 24234451 30021884 physical association cross-linking study IntAct
MYH10 PSMD8 24234451 30021884 physical association cross-linking study IntAct
MYH10 TDRD6 24234451 30021884 physical association cross-linking study IntAct
MYH10 ZDBF2 24234451 30021884 physical association cross-linking study IntAct
L1TD1 MYH10 24234451 25702638 association anti bait coimmunoprecipitation IntAct
ROCK1 MYH10 15774750 27898060 stimulant N/A OmniPath
PRKCZ MYH10 16611744 27898060 inhibition N/A OmniPath
CSNK2A1 MYH10 25869664 27898060 9485326 N/A N/A OmniPath

Visualization










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