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GENE：FLNA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FLNA
FullNmae filamin A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3754
EnsembleID ENSG00000196924
Uniprot P21333

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FLNA mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FLNA disulfidptosis 38738994 Furthermore, employing a random forest model, we identified four diagnostic disulfidptosis regulators including FLNA, SLC7A11, NUBPL, and RAC1 potentially predictive of OP risk. retulator signature

Go Annotation:

GeneSymbol Go id
FLNA GO:0001525,GO:0001664,GO:0001837,GO:0001974,GO:0003007,GO:0003723,GO:0005080,GO:0005515,GO:0005576,GO:0005634,GO:0005730,GO:0005737,GO:0005802,GO:0005829,GO:0005829,GO:0005884,GO:0005886,GO:0005903,GO:0005911,GO:0005925,GO:0007195,GO:0007597,GO:0010572,GO:0010977,GO:0015459,GO:0015629,GO:0015629,GO:0016020,GO:0016479,GO:0019900,GO:0021943,GO:0021987,GO:0030018,GO:0030036,GO:0030334,GO:0030863,GO:0031267,GO:0031523,GO:0032233,GO:0032432,GO:0034394,GO:0034988,GO:0035855,GO:0042177,GO:0042307,GO:0042789,GO:0042803,GO:0043066,GO:0043113,GO:0043123,GO:0043198,GO:0043204,GO:0043433,GO:0044295,GO:0044319,GO:0044325,GO:0045022,GO:0045184,GO:0045216,GO:0045296,GO:0046332,GO:0048471,GO:0048680,GO:0050808,GO:0050821,GO:0051015,GO:0051020,GO:0051209,GO:0051220,GO:0051764,GO:0060271,GO:0070062,GO:0070527,GO:0071526,GO:0072659,GO:0090042,GO:0090307,GO:0097368,GO:0097440,GO:0098794,GO:0098978,GO:0140297,GO:1900026,GO:1901381,GO:1902396,GO:1905000,GO:1905031,GO:1990779,GO:2000179,GO:2001046,GO:2001224

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FLNA hsa:2316 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
FLNA hsa:2316 path:hsa04510 Focal adhesion - Homo sapiens (human)
FLNA hsa:2316 path:hsa05132 Salmonella infection - Homo sapiens (human)
FLNA hsa:2316 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FLNA MAP3K14 10679398 15536066 16849481 17237376 21277899 21807870 26192618 27242793 association N/A ACSN
FLNA VAV1 16849481 21277899 26192618 27242793 interaction type N/A ACSN
CD28 FLNA 10426994 11907067 1313950 15197224 15536084 16713974 22437870 26192618 7523569 9359474 interaction type N/A ACSN
FLNA PRKCQ 16849481 21277899 26192618 27242793 interaction type N/A ACSN
TLR1 FLNA 16482509 23180781 physical association two hybrid InnateDB
TLR10 FLNA 16482509 23180781 physical association two hybrid InnateDB
ELP1 FLNA 18303054 23180781 physical association anti tag coimmunoprecipitation InnateDB
CFTR FLNA 17235394 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSGA10 FLNA 20797700 23180781 physical association affinity chromatography technology InnateDB
PLCG1 FLNA 17474147 23180781 physical association peptide array InnateDB
ISG15 FLNA 16009940 23180781 physical association unspecified method InnateDB
FLNA FLNA 12198493 15642266 19923718 23084743 24578532 25352621 26760998 29145629 3378035 physical association inferred by curator Reactome
FLNA RNASEL 23084743 24578532 25352621 26760998 29145629 physical association inferred by curator Reactome
FLNA MAP2K4 23331499 9006895 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 FLNA 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CTCF FLNA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FLNA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FLNA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A FLNA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SMAD1 FLNA N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 FLNA 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00003D5391 FLNA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A7F58 FLNA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 FLNA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE FLNA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D FLNA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC FLNA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000451A1 FLNA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000171525 FLNA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D FLNA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000183BED FLNA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000153377 FLNA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000170CF4 FLNA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000001EB3 FLNA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001CC864 FLNA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F FLNA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 FLNA 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CAMK2A FLNA 22135298 phosphorylation N/A PhosphoSite
PRKACA FLNA 22135298 phosphorylation N/A PhosphoSite
CDK1 FLNA 22135298 phosphorylation N/A PhosphoSite
MAP3K7 FLNA 22135298 phosphorylation N/A PhosphoSite
RPS6KA1 FLNA 22135298 phosphorylation N/A PhosphoSite
PAK1 FLNA 22135298 phosphorylation N/A PhosphoSite
AKT1 FLNA 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
MAPRE1 FLNA 25348397 N/A physical interaction ComPPI
ARPC3 FLNA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC73 FLNA 25348397 N/A physical interaction ComPPI
FAM90A1 FLNA 25348397 N/A physical interaction ComPPI
CDC42 FLNA 10051605 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PPP1CC FLNA 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
ISG15 FLNA 25348397 N/A physical interaction ComPPI
NPM1 FLNA 25348397 N/A physical interaction ComPPI
ACTG1 FLNA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CFL1 FLNA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TP53BP1 FLNA 25348397 N/A physical interaction ComPPI
LMNA FLNA 25348397 N/A two hybrid,physical interaction ComPPI
MCM5 FLNA 25348397 N/A physical interaction ComPPI
ITGB5 FLNA 14525934 16355270 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
ACTB FLNA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YWHAG FLNA 14525934 15324660 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PPP1CB FLNA 25348397 N/A physical interaction ComPPI
CALM1 FLNA 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
KEAP1 FLNA 25348397 N/A physical interaction ComPPI
MCM2 FLNA 25348397 N/A physical interaction ComPPI
RAC1 FLNA 10051605 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
HSP90AB1 FLNA 16263121 24234451 25241761 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,proximity ligation assay ComPPI,IntAct
CRK FLNA 17474147 24234451 25241761 25348397 physical association peptide array,physical interaction,proximity ligation assay ComPPI,IntAct
VBP1 FLNA 25348397 N/A physical interaction ComPPI
PRKACB FLNA 15225631 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
EHMT2 FLNA 24234451 25348397 26028330 association anti tag coimmunoprecipitation ComPPI,IntAct
PFDN4 FLNA 25348397 N/A physical interaction ComPPI
CD44 FLNA 25348397 N/A physical interaction ComPPI
PAK1 FLNA 25348397 N/A two hybrid,two hybrid,physical interaction,in vitro,in vivo ComPPI
TXNIP FLNA 25348397 N/A physical interaction ComPPI
DAB2 FLNA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BTK FLNA 21080425 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
SYK FLNA 25348397 N/A physical interaction ComPPI
REL FLNA 25348397 N/A physical interaction ComPPI
PIK3R1 FLNA 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PRKCA FLNA 12704190 14525934 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
SRC FLNA 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SH2B3 FLNA 11163396 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,OmniPath
CD81 FLNA 25348397 N/A physical interaction ComPPI
CD59 FLNA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GRB2 FLNA 12577067 17474147 21706016 24234451 25348397 association,physical association anti tag coimmunoprecipitation,peptide array,pull down,physical interaction ComPPI,IntAct
JUN FLNA 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
AR FLNA 12682292 14525934 25348397 N/A two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
SMAD3 FLNA 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
RBM39 FLNA 25348397 N/A physical interaction ComPPI
TPM2 FLNA 25348397 N/A physical interaction ComPPI
SMAD5 FLNA 11278410 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
MAPK14 FLNA 11390380 14525934 20936779 24234451 25348397 physical association experimental interaction detection,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vivo ComPPI,HPRD,IntAct
OPRM1 FLNA 14525934 14573758 24234451 25348397 27898060 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,in vitro,in vivo,confocal microscopy,two hybrid ComPPI,HPRD,IntAct,OmniPath
LIG4 FLNA 25348397 N/A physical interaction ComPPI
ITGB1 FLNA 15225631 17690686 18177638 24234451 25348397 9722563 colocalization,physical association anti bait coimmunoprecipitation,two hybrid,pull down,physical interaction,fluorescence microscopy,in vivo ComPPI,IntAct
RHOA FLNA 10051605 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FLNA RALA 10051605 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
FLNA VHL 12169691 14525934 25348397 8674032 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
FLNA BRCA2 11602572 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
FLNA PSEN2 14525934 24234451 25348397 9437013 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD,IntAct
FLNA CAV1 10637311 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
FLNA GRM8 11943148 14525934 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
FLNA CASR 11390379 11390380 14525934 25348397 27898060 N/A two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
FLNA MAP2K4 14525934 25348397 9006895 N/A experimental interaction detection,in vivo ComPPI,HPRD
FLNA TRIO 11146652 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
FLNA TRAF2 10617615 14525934 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
FLNA CAMK2G 24234451 25241761 25348397 physical association physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,IntAct
FLNA FLNB 12393796 14525934 22939629 24234451 25348397 26344197 26496610 27898060 colocalization,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,fluorescence microscopy,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
FLNA GRM5 25348397 N/A in vivo ComPPI
FLNA MYOT 11038172 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FLNA SIGLEC10 12055638 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
FLNA NPHP1 12006559 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
FLNA FBLIM1 12679033 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
FLNA CMIP 14525934 15128042 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
FLNA TNIP2 12753905 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
FLNA SHBG 14525934 15862967 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
FLNA KCNJ2 12923176 14525934 24234451 25348397 27898060 physical association two hybrid,experimental interaction detection,pull down,in vitro,two hybrid ComPPI,HPRD,IntAct,OmniPath
FLNA TLR10 14525934 16482509 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
FLNA DRD1 10692483 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
FLNA ARRB2 14525934 16611986 17620599 24234451 25348397 association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
FLNA ARRB1 14525934 16611986 17620599 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
FLNA CEACAM1 14525934 16291724 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
FLNA DRD2 11911837 14525934 25348397 N/A two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
FLNA DRD3 11911837 14525934 25348397 N/A two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
FLNA TTN 16902413 24234451 25348397 physical association two hybrid ComPPI,IntAct
FLNA CALCR 12531889 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD,OmniPath
FLNA ARHGAP24 14525934 16862148 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,fluorescence microscopy,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
FLNA PCBP2 14525934 25348397 8871564 N/A two hybrid,two hybrid ComPPI,HPRD
FLNA MTNR1A 14525934 17215244 24234451 25348397 26514267 physical association two hybrid,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
FLNA MTNR1B 14525934 17215244 24234451 25348397 26514267 association,physical association two hybrid,experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
FLNA CCNB1 14525934 17408621 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
FLNA SELE 14525934 25348397 8609175 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
FLNA SVIL 14525934 20309963 24234451 25348397 26496610 association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
FLNA F3 14525934 25348397 27898060 9490735 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
FLNA FURIN 14525934 25348397 9412467 N/A experimental interaction detection,in vivo ComPPI,HPRD
FLNA GRIK3 11943148 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FLNA GRIK1 11943148 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FLNA ITGB7 11781567 14525934 15225631 17690686 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,filter binding,pull down,physical interaction,saturation binding,in vitro ComPPI,HPRD,IntAct
FLNA PSEN1 14525934 24234451 25348397 9437013 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,genetic,in vivo,two hybrid ComPPI,HPRD,IntAct
FLNA ITGB3 24234451 25348397 25849143 physical association nuclear magnetic resonance,surface plasmon resonance,physical interaction,surface plasmon resonance array ComPPI,IntAct
FLNA ITGB6 25348397 N/A physical interaction ComPPI
FLNA DCN 12106908 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
FLNA GP1BA 11700320 24234451 25241761 25348397 27898060 physical association physical interaction,proximity ligation assay ComPPI,IntAct,OmniPath
FLNA FILIP1 25348397 N/A physical interaction ComPPI
FLNA OTUD1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA OTUD5 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA USP45 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA G3BP1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA DMWD 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA CAMKK2 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA APC 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FLNA BANF1 25348397 N/A physical interaction ComPPI
FLNA AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA TJP1 16944923 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
FLNA HDAC5 25348397 N/A physical interaction ComPPI
FLNA SIRT7 25348397 N/A physical interaction ComPPI
FLNA ASB2 18799729 21737450 21750192 24052262 25348397 27898060 N/A physical interaction ComPPI,OmniPath
FLNA CUL3 25348397 N/A physical interaction ComPPI
FLNA CDK2 25348397 N/A physical interaction ComPPI
FLNA KCND2 25348397 N/A physical interaction ComPPI
FLNA KCNE4 25348397 N/A physical interaction ComPPI
FLNA MYH9 25348397 N/A physical interaction ComPPI
FLNA LGALS1 25348397 N/A physical interaction ComPPI
FLNA DBN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA CPLX1 25348397 N/A physical interaction ComPPI
FLNA RANBP2 25348397 N/A physical interaction ComPPI
FLNA SRRM2 25348397 N/A physical interaction ComPPI
FLNA SRSF11 25348397 N/A physical interaction ComPPI
FLNA IKBIP 25348397 N/A physical interaction ComPPI
FLNA TRA2B 25348397 N/A physical interaction ComPPI
FLNA ESR1 21182205 24234451 25348397 25604459 association affinity chromatography technology,cosedimentation through density gradient,physical interaction,tandem affinity purification ComPPI,IntAct
FLNA BRCA1 16713569 20305393 22051193 25348397 27898060 N/A physical interaction ComPPI,OmniPath
FLNA ECT2 25348397 N/A physical interaction ComPPI
FLNA MDC1 25348397 N/A physical interaction ComPPI
FLNA TSGA10 25348397 N/A physical interaction ComPPI
FLNA ELP1 25348397 N/A physical interaction ComPPI
FLNA SMURF1 25348397 N/A physical interaction ComPPI
FLNA HSP90AA1 25348397 N/A physical interaction ComPPI
FLNA HSP90AA2P 25348397 N/A physical interaction ComPPI
FLNA MYC 21150319 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
FLNA FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
FLNA VCAM1 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
FLNA IQCB1 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA SYNPO2 25348397 N/A physical interaction ComPPI
FLNA ITGA4 10604475 24234451 25348397 physical association affinity chromatography technology,physical interaction ComPPI,IntAct
FLNA MYBL2 25348397 N/A physical interaction ComPPI
FLNA USP19 25348397 N/A physical interaction ComPPI
FLNA PAN2 25348397 N/A physical interaction ComPPI
FLNA IGSF8 25348397 N/A physical interaction ComPPI
FLNA ICAM1 25348397 N/A physical interaction ComPPI
FLNA BSG 25348397 N/A physical interaction ComPPI
FLNA ADRB2 25348397 N/A physical interaction ComPPI
FLNA HNRNPD 25348397 N/A physical interaction ComPPI
FLNA AKAP12 25348397 N/A physical interaction ComPPI
FLNA DYNC1H1 25348397 N/A physical interaction ComPPI
FLNA DYNC1LI2 25348397 N/A physical interaction ComPPI
FLNA RPS23 25348397 N/A physical interaction ComPPI
FLNA RPA2 25348397 N/A physical interaction ComPPI
FLNA RPA3 25348397 N/A physical interaction ComPPI
FLNA ZBTB1 25348397 N/A physical interaction ComPPI
FLNA STAU1 25348397 N/A physical interaction ComPPI
FLNA TRIM55 25348397 N/A physical interaction ComPPI
FLNA TP53 25348397 N/A physical interaction ComPPI
FLNA TCF4 25348397 N/A physical interaction ComPPI
FLNA HSPB7 25348397 N/A physical interaction ComPPI
FLNA ADAMTSL4 25348397 N/A physical interaction ComPPI
FLNA LGALS14 24234451 25348397 27107012 physical association physical interaction,validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
FLNA KLHL12 25348397 N/A physical interaction ComPPI
FLNA RFLNA 25348397 N/A physical interaction ComPPI
FLNA CUL7 25348397 N/A physical interaction ComPPI
FLNA OBSL1 25348397 N/A physical interaction ComPPI
FLNA CCDC8 25348397 N/A physical interaction ComPPI
FLNA TXNDC16 25348397 N/A physical interaction ComPPI
FLNA FOXRED2 25348397 N/A physical interaction ComPPI
FLNA SIRT6 25348397 N/A physical interaction ComPPI
FLNA ABCE1 25348397 N/A physical interaction ComPPI
FLNA FBXW11 25348397 N/A physical interaction ComPPI
FLNA CARD8 25348397 N/A physical interaction ComPPI
FLNA HNRNPA1 25348397 N/A physical interaction ComPPI
FLNA ACAD10 25348397 N/A physical interaction ComPPI
FLNA DNAAF5 25348397 N/A physical interaction ComPPI
FLNA NMD3 25348397 N/A physical interaction ComPPI
FLNA PDIA3 25348397 N/A physical interaction ComPPI
FLNA PFDN2 25348397 N/A physical interaction ComPPI
FLNA PFDN5 25348397 N/A physical interaction ComPPI
FLNA TDRD15 25348397 N/A physical interaction ComPPI
FLNA NTRK1 25348397 N/A physical interaction ComPPI
FLNA PPME1 25348397 N/A physical interaction ComPPI
FLNA ACTN4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA AP2A1 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
FLNA AP2B1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA ANXA2P2 25348397 N/A physical interaction ComPPI
FLNA ANXA2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA CAPZA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA CAPZA2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA CAPZB 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
FLNA CFL2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA AP2M1 25348397 N/A physical interaction ComPPI
FLNA CLTA 25348397 N/A physical interaction ComPPI
FLNA CLTB 25348397 N/A physical interaction ComPPI
FLNA CLTC 25348397 N/A physical interaction ComPPI
FLNA CPM 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA DAPK3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA DSG2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA CTTN 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA EPS15 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA FLII 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA MYH11 25348397 N/A physical interaction ComPPI
FLNA MYO1C 25348397 N/A physical interaction ComPPI
FLNA PDLIM7 25348397 N/A physical interaction ComPPI
FLNA SYNPO 25348397 N/A physical interaction ComPPI
FLNA LIMA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA ANLN 25348397 N/A physical interaction ComPPI
FLNA MYO5C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA MYO19 25348397 N/A physical interaction ComPPI
FLNA MYO18A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA FLOT2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA GNAI1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA GNAS 25348397 N/A physical interaction ComPPI
FLNA GNAS 25348397 N/A physical interaction ComPPI
FLNA GNAS 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA GNB2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA GSN 25348397 N/A physical interaction ComPPI
FLNA ITPR3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA ABLIM1 25348397 N/A physical interaction ComPPI
FLNA MYO1B 25348397 N/A physical interaction ComPPI
FLNA MYO1E 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA MYO5A 25348397 N/A physical interaction ComPPI
FLNA MYO6 25348397 N/A physical interaction ComPPI
FLNA PPP1R12A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA PALM 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA PIK3C2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA PLEC 25348397 N/A physical interaction ComPPI
FLNA PPP1CA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA TWF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA S100A10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA SEC13 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA FSCN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA UAP1 25348397 N/A physical interaction ComPPI
FLNA SPTAN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA SPTBN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA SPTBN2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA ITPRID2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA TMOD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA TPM1 25348397 N/A physical interaction ComPPI
FLNA TPM4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA CORO2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA LUZP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA SORBS2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA CLINT1 25348397 N/A physical interaction ComPPI
FLNA ARHGAP11A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA WDR1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA ARPC4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA ARPC1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA ACTR3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA ACTR2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA FLOT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA BASP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA AKAP2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA CEP162 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA PALLD 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA MPRIP 25348397 N/A physical interaction ComPPI
FLNA COBL 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA CORO1C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA PLEKHG3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA RAI14 25348397 N/A physical interaction ComPPI
FLNA TES 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA ZBTB20 25348397 N/A physical interaction ComPPI
FLNA TMOD3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA BMP2K 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA CORO1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA CRACD 25348397 N/A physical interaction ComPPI
FLNA ARHGAP21 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA AFAP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA INF2 25348397 N/A physical interaction ComPPI
FLNA CYBRD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA ARPC5L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA KCTD10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA ANTXR1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA PPP1R9B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA STON2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA DIXDC1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA SSH2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA PHLDB2 20236936 24234451 25348397 26496610 27898060 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
FLNA NEXN 25348397 N/A physical interaction ComPPI
FLNA SPECC1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA MISP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA CHMP4B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA PPP1R18 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA TPRN 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA MAP3K3 14743216 24234451 25241761 25348397 physical association physical interaction,tandem affinity purification,proximity ligation assay ComPPI,IntAct
FLNA CRY1 25348397 N/A physical interaction ComPPI
FLNA CRY2 25348397 N/A physical interaction ComPPI
FLNA ALKBH3 25348397 N/A physical interaction ComPPI
FLNA NLGN3 24234451 25348397 25464930 colocalization,association anti bait coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
FLNA ARFGEF2 25348397 N/A physical interaction ComPPI
FLNA CDH1 25348397 N/A physical interaction ComPPI
FLNA CAPN6 25348397 N/A physical interaction ComPPI
FLNA APOH 25348397 N/A physical interaction ComPPI
FLNA RAB8B 25348397 N/A physical interaction ComPPI
FLNA CYLD 25348397 N/A physical interaction ComPPI
FLNA MCPH1 25348397 N/A physical interaction ComPPI
FLNA HEY1 25348397 N/A physical interaction ComPPI
FLNA DPP9 25348397 N/A physical interaction ComPPI
FLNA CENPA 25348397 N/A physical interaction,tandem affinity purification ComPPI
FLNA TRIM24 22307607 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA POLR1C 22307607 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA ITGA2B 25348397 N/A nuclear magnetic resonance,physical interaction,surface plasmon resonance array ComPPI
FLNA ABCA1 24234451 25170080 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLNA IKBKB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
FLNA IKBKG 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
FLNA MAP3K1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
FLNA RIPK3 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
FLNA TAB2 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
FLNA MAP3K7 25348397 N/A tandem affinity purification ComPPI
FLNA TNFRSF1B 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
FLNA ITGB4 15225631 24234451 25348397 physical association pull down ComPPI,IntAct
FLNA YWHAZ 15161933 24234451 25348397 physical association pull down ComPPI,IntAct
FLNA CCNB2 17408621 24234451 25348397 phosphorylation reaction,colocalization,physical association anti bait coimmunoprecipitation,far western blotting,pull down,protein kinase assay,imaging technique ComPPI,IntAct
FLNA RPS9 17461779 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
FLNA PRR5 25348397 N/A anti tag coimmunoprecipitation ComPPI
FLNA ARHGAP8 25348397 N/A anti tag coimmunoprecipitation ComPPI
FLNA ABL1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
FLNA FYN 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
FLNA PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
FLNA MYB 18548008 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
FLNA SLX4 19596235 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
FLNA ULK2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
FLNA GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
FLNA FOXC1 15684392 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,fluorescence microscopy ComPPI,IntAct
FLNA NRP1 24021649 24234451 25348397 27898060 N/A isothermal titration calorimetry,surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct,OmniPath
FLNA ESR2 24234451 25348397 25604459 association tandem affinity purification ComPPI,IntAct
FLNA DUX4 24234451 25348397 26816005 association pull down ComPPI,IntAct
FLNA TUBB3 24234451 25348397 27291054 association pull down ComPPI,IntAct
FLNA TUBA1A 24234451 25348397 27291054 association pull down ComPPI,IntAct
JUP FLNA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DYNC1LI1 FLNA 25348397 N/A physical interaction ComPPI
RPA1 FLNA 25348397 N/A physical interaction ComPPI
HMGB2 FLNA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IQGAP1 FLNA 25348397 N/A physical interaction ComPPI
H3C1 FLNA 25348397 N/A physical interaction ComPPI
ILF2 FLNA 25348397 N/A physical interaction ComPPI
GNG12 FLNA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FABP1 FLNA 24234451 25348397 25910212 physical association physical interaction,two hybrid array,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
GRM4 FLNA 11943148 14525934 N/A experimental interaction detection HPRD
GRM7 FLNA 11943148 14525934 N/A experimental interaction detection HPRD
ERBB3 FLNA 14525934 16729043 N/A experimental interaction detection HPRD
FLNA FLNA 2391361 24234451 physical association cross-linking study IntAct
FLNA CALM2 24234451 26496610 association anti tag coimmunoprecipitation IntAct
WTAP FLNA 24234451 29507755 association anti tag coimmunoprecipitation IntAct
METTL14 FLNA 24234451 29507755 association anti tag coimmunoprecipitation IntAct
FLNA DHX8 24234451 30021884 physical association cross-linking study IntAct
FLNA PRPF19 24234451 30021884 physical association cross-linking study IntAct
MAMDC2 FLNA 24234451 30021884 physical association cross-linking study IntAct
FLNA MAP3K2 24234451 30021884 physical association cross-linking study IntAct
FLNA CHD2 24234451 30021884 physical association cross-linking study IntAct
FLNA DND1 24234451 30021884 physical association cross-linking study IntAct
FLNA ZGRF1 24234451 30021884 physical association cross-linking study IntAct
FLNA PKD2 19879844 27898060 N/A N/A OmniPath
FLNA FLNC 24019900 27898060 N/A N/A OmniPath
FLNA PDLIM2 15505042 27898060 N/A N/A OmniPath
PPP3CA FLNA 16442073 27898060 inhibition N/A OmniPath
PLCG1 FLNA 17474147 27898060 N/A N/A OmniPath
PRKACA FLNA 15228085 207708 27898060 stimulant N/A OmniPath
FYN FLNA 11290523 15024089 17474147 27898060 N/A N/A OmniPath
RPS6KA1 FLNA 10775444 12198493 15024089 15228085 16442073 20179208 25061177 25666618 25944616 27898060 stimulant N/A OmniPath
FLNA MAP2K4 27898060 9006895 stimulant N/A OmniPath
TLR10 FLNA 16482509 27898060 N/A N/A OmniPath
CDK1 FLNA 17408621 25445790 27898060 N/A N/A OmniPath
PAK1 FLNA 12198493 27898060 stimulant N/A OmniPath
ISG15 FLNA 16009940 27898060 N/A N/A OmniPath
ROR2 FLNA 18667433 27898060 stimulant N/A OmniPath
CAMK2A FLNA 11290523 27898060 N/A N/A OmniPath
ELP1 FLNA 18303054 27898060 N/A N/A OmniPath
TSGA10 FLNA 20797700 27898060 N/A N/A OmniPath
CFTR FLNA 17235394 27898060 N/A N/A OmniPath
PPP3CB FLNA 16442073 27898060 inhibition N/A OmniPath
TLR1 FLNA 16482509 27898060 N/A N/A OmniPath
PPP3CC FLNA 16442073 27898060 inhibition N/A OmniPath
CAMK2G FLNA 11290523 25241761 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B3BB7 FLNA 27087310 direct interaction,inhibition N/A NPInter

Visualization










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