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GENE：DSTN

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DSTN
FullNmae destrin, actin depolymerizing factor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15750
EnsembleID ENSG00000125868
Uniprot P60981

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DSTN disulfidptosis 40258895 A total of 13,316 DEGs were identified, among which 11 disulfidptosis-related genes were screened: INF2, CD2AP, PDLIM1, ACTN4, MYH10, MYH9, FLNA, FLNB, TLN1, MYL6, ACTB, CAPZB, DSTN, and IQGAP1. retulator signature

Go Annotation:

GeneSymbol Go id
DSTN GO:0005515,GO:0005737,GO:0008154,GO:0015629,GO:0030042,GO:0030043,GO:0030836,GO:0030864,GO:0051014,GO:0051015,GO:0051015,GO:0070062

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
DSTN ACTB 23180781 25416956 physical association two hybrid InnateDB
DSTN ACTG1 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
AR DSTN 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 DSTN 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 DSTN 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 DSTN 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 DSTN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DSTN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DSTN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DSTN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DSTN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF DSTN 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005651EE DSTN 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002CAE0C DSTN 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005E1A16 DSTN 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 DSTN 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002DD349 DSTN 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000183BED DSTN 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC864 DSTN 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 DSTN 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000321A1A DSTN 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDA4 DSTN 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005194EC DSTN 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000023F8DA DSTN 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000101787 DSTN 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 DSTN 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
LIMK2 DSTN 22135298 phosphorylation N/A PhosphoSite
LIMK1 DSTN 22135298 phosphorylation N/A PhosphoSite
DSTN SSH1 25361965 interaction type N/A PTMCode2
SSH1 DSTN 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NMI DSTN 25348397 N/A physical interaction ComPPI
EIF1B DSTN 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SGTA DSTN 25348397 N/A physical interaction ComPPI
LDHB DSTN 25348397 N/A physical interaction ComPPI
LDHA DSTN 25348397 N/A physical interaction ComPPI
ISG15 DSTN 25348397 N/A physical interaction ComPPI
NPM1 DSTN 25348397 N/A physical interaction ComPPI
PCBP1 DSTN 25348397 N/A physical interaction ComPPI
ACTG1 DSTN 14525934 16189514 24234451 25348397 25416956 8399167 physical association experimental interaction detection,physical interaction,mammalian protein protein interaction trap,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
VCP DSTN 25348397 N/A physical interaction ComPPI
ACTB DSTN 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
PPP1CB DSTN 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MCM2 DSTN 25348397 N/A physical interaction ComPPI
HSPB8 DSTN 25348397 N/A physical interaction ComPPI
DSTN TESK2 25348397 N/A in vitro ComPPI
DSTN SHBG 14525934 15862967 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
DSTN SMAD9 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DSTN RRBP1 25348397 N/A physical interaction ComPPI
DSTN SSH1 25348397 N/A physical interaction ComPPI
DSTN CDK2 25348397 N/A physical interaction ComPPI
DSTN PIEZO1 25348397 N/A physical interaction ComPPI
DSTN MYG1 25348397 N/A physical interaction ComPPI
DSTN URM1 25348397 N/A physical interaction ComPPI
DSTN PTMA 25348397 N/A physical interaction ComPPI
DSTN DPP3 25348397 N/A physical interaction ComPPI
DSTN IGFBP7 25348397 N/A physical interaction ComPPI
DSTN OTUB1 25348397 N/A physical interaction ComPPI
DSTN CROT 25348397 N/A physical interaction ComPPI
DSTN SLIRP 25348397 N/A physical interaction ComPPI
DSTN TPM2 25348397 N/A physical interaction ComPPI
DSTN PPP4R2 25348397 N/A physical interaction ComPPI
DSTN DNPH1 25348397 N/A physical interaction ComPPI
DSTN SEC24A 25348397 N/A physical interaction ComPPI
DSTN MYH11 25348397 N/A physical interaction ComPPI
DSTN GFUS 25348397 N/A physical interaction ComPPI
DSTN RNF114 25348397 N/A physical interaction ComPPI
DSTN ITSN1 25348397 N/A physical interaction ComPPI
DSTN STMN2 25348397 N/A physical interaction ComPPI
DSTN SRSF2 25348397 N/A physical interaction ComPPI
DSTN MCFD2 25348397 N/A physical interaction ComPPI
DSTN PEX19 25348397 N/A physical interaction ComPPI
DSTN PALLD 25348397 N/A physical interaction ComPPI
DSTN LIMD1 25348397 N/A physical interaction ComPPI
DSTN PXN 25348397 N/A physical interaction ComPPI
DSTN S100A9 25348397 N/A physical interaction ComPPI
DSTN UBE2B 25348397 N/A physical interaction ComPPI
DSTN STAT6 25348397 N/A physical interaction ComPPI
DSTN POMP 25348397 N/A physical interaction ComPPI
DSTN TOM1L2 25348397 N/A physical interaction ComPPI
DSTN UNK 25348397 N/A physical interaction ComPPI
DSTN ZFYVE19 25348397 N/A physical interaction ComPPI
DSTN UBA3 25348397 N/A physical interaction ComPPI
DSTN DNAJB12 25348397 N/A physical interaction ComPPI
DSTN SEC23IP 25348397 N/A physical interaction ComPPI
DSTN PSMD9 25348397 N/A physical interaction ComPPI
DSTN SP100 25348397 N/A physical interaction ComPPI
DSTN PDLIM5 25348397 N/A physical interaction ComPPI
DSTN LAMTOR5 25348397 N/A physical interaction ComPPI
DSTN PUM1 25348397 N/A physical interaction ComPPI
DSTN MCM7 25348397 N/A physical interaction ComPPI
DSTN PTMS 25348397 N/A physical interaction ComPPI
DSTN ITGB1 25348397 N/A physical interaction ComPPI
DSTN TUBA1C 25348397 N/A physical interaction ComPPI
DSTN ACTA1 25348397 N/A physical interaction ComPPI
DSTN CFL2 25348397 N/A physical interaction ComPPI
DSTN TAX1BP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DSTN EED 25348397 N/A physical interaction ComPPI
DSTN ABAT 25348397 N/A physical interaction ComPPI
DSTN ALDH4A1 25348397 N/A physical interaction ComPPI
DSTN CRIP1 25348397 N/A physical interaction ComPPI
DSTN HTRA2 25348397 N/A physical interaction ComPPI
DSTN KYNU 25348397 N/A physical interaction ComPPI
DSTN PIR 25348397 N/A physical interaction ComPPI
DSTN SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
DSTN ST13 25348397 N/A physical interaction ComPPI
DSTN ST13P4 25348397 N/A physical interaction ComPPI
DSTN WDR1 25348397 N/A physical interaction ComPPI
DSTN HIBCH 25348397 N/A physical interaction ComPPI
DSTN HSPE1 25348397 N/A physical interaction ComPPI
DSTN LDHAL6A 25348397 N/A physical interaction ComPPI
DSTN MEMO1 25348397 N/A physical interaction ComPPI
DSTN NME2 25348397 N/A physical interaction ComPPI
DSTN PRDX5 25348397 N/A physical interaction ComPPI
DSTN SPR 25348397 N/A physical interaction ComPPI
DSTN TPI1 25348397 N/A physical interaction ComPPI
DSTN MYH9 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DSTN MYO1C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DSTN MYO18A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DSTN FOXA1 25348397 N/A physical interaction ComPPI
DSTN G3BP1 25348397 N/A physical interaction ComPPI
DSTN CFTR 25348397 N/A physical interaction ComPPI
DSTN PINX1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DSTN TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DSTN IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DSTN GH1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DSTN JUN 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
DSTN SUMO1P1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DSTN KSR2 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
RNH1 DSTN 25348397 N/A physical interaction ComPPI
TTC1 DSTN 25348397 N/A physical interaction ComPPI
MIF DSTN 25348397 N/A physical interaction ComPPI
OTULIN DSTN 25348397 N/A physical interaction ComPPI
ATP5PD DSTN 24234451 30021884 physical association cross-linking study IntAct
LIMK2 DSTN 27898060 7615564 N/A N/A OmniPath
TESK2 DSTN 11418599 19413330 19651622 20068231 27898060 inhibition N/A OmniPath
SSH1 DSTN 11832213 27898060 N/A N/A OmniPath

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