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GENE：MT1F

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MT1F
FullNmae metallothionein 1F
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7398
EnsembleID ENSG00000198417
Uniprot P04733

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MT1F cuproptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MT1F cuproptosis 38495196 Cuproptosis-related genes were manually curated, and differentially expressed cuproptosis-related genes (DECuGs) were identified.Then, the 16 DECuGs were obtained by the intersection of the 5018 DEGs and 63 cuproptosis-related genes. 63 cuproptosis-related genes
MT1F cuproptosis 35964468 Cuproptosis-related gene sets were obtained from a previous study [9] and combined with the Molecular Signature Database (MsigDB) v7.0 database (http://www.gsea-msigdb.org/gsea/msigdb/, GOBP_CELLULAR_COPPER_ION_HOMEOSTASIS, GOBP_CELLULAR_RESPONSE_TO_COPPER_ION). Cuproptosis-related gene sets obtained from Molecular Signature Database (MsigDB) v7.11 database.
MT1F cuproptosis 36313717 The details of ninety-six candidate cuproptosis-related genes involved in the copper homeostasis regulatory pathway, copper metabolism diseases, mitochondrial respiratory, and iron-sulfur cluster proteins were exhibited in聽Table S1. Genes of iron-sulfur cluster related proteins
MT1F cuproptosis 36211378 Forty-three cuproptosis-related genes were selected from the review of Chang et al. (13) 43 cuproptosis-related genes in the study

Go Annotation:

GeneSymbol Go id
MT1F GO:0005515,GO:0005634,GO:0005634,GO:0005737,GO:0005737,GO:0006882,GO:0008270,GO:0010273,GO:0045926,GO:0046872,GO:0071276,GO:0071276,GO:0071280,GO:0071294,GO:0071294

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MT1F hsa:4494 path:hsa04978 Mineral absorption - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CEBPA MT1F 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MT1F 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXF2 MT1F 19562724 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 MT1F 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 MT1F 19074876 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
MT1F SHBG 14525934 15862967 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
MT1F NOP2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct

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