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GENE：MT1G

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MT1G
FullNmae metallothionein 1G
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7399
EnsembleID ENSG00000125144
Uniprot P13640

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MT1G ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MT1G ferroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
MT1G cuproptosis 37904461 ATOX1, SUMF1, MT1G, ATP7B, FDX1, and LIAS are cuproptosis-related hub genes of active UC. retulator signature
MT1G cuproptosis 38495196 Cuproptosis-related genes were manually curated, and differentially expressed cuproptosis-related genes (DECuGs) were identified.Then, the 16 DECuGs were obtained by the intersection of the 5018 DEGs and 63 cuproptosis-related genes. 63 cuproptosis-related genes
MT1G cuproptosis 35964468 Cuproptosis-related gene sets were obtained from a previous study [9] and combined with the Molecular Signature Database (MsigDB) v7.0 database (http://www.gsea-msigdb.org/gsea/msigdb/, GOBP_CELLULAR_COPPER_ION_HOMEOSTASIS, GOBP_CELLULAR_RESPONSE_TO_COPPER_ION). Cuproptosis-related gene sets obtained from Molecular Signature Database (MsigDB) v7.12 database.
MT1G cuproptosis 36313717 The details of ninety-six candidate cuproptosis-related genes involved in the copper homeostasis regulatory pathway, copper metabolism diseases, mitochondrial respiratory, and iron-sulfur cluster proteins were exhibited in聽Table S1. Genes of iron-sulfur cluster related proteins
MT1G cuproptosis 36211378 Forty-three cuproptosis-related genes were selected from the review of Chang et al. (13) 43 cuproptosis-related genes in the study

Go Annotation:

GeneSymbol Go id
MT1G GO:0005515,GO:0005634,GO:0005634,GO:0005737,GO:0005737,GO:0006882,GO:0008270,GO:0010273,GO:0030224,GO:0035924,GO:0042117,GO:0045926,GO:0046872,GO:0071276,GO:0071276,GO:0071280,GO:0071280,GO:0071294,GO:0071294,GO:0071294

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MT1G hsa:4495 path:hsa04978 Mineral absorption - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F1 MT1G 15735762 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
E2F2 MT1G 15735762 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
E2F3 MT1G 15735762 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
E2F4 MT1G 15735762 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
E2F5 MT1G 15735762 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF MT1G 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
SHBG MT1G 14525934 15862967 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD

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