GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
MT1M
FullNmae
metallothionein 1M
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:14296
EnsembleID
ENSG00000205364
Uniprot
Q8N339
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
MT1M
cuproptosis
36466876 Overall, 25 CuDEGs were identified, including ABCB6, BACE1, FDX1, GLS, LIAS, MT1M, PDHA1, etc.
retulator signature
MT1M
cuproptosis
38495196 Cuproptosis-related genes were manually curated, and differentially expressed cuproptosis-related genes (DECuGs) were identified.Then, the 16 DECuGs were obtained by the intersection of the 5018 DEGs and 63 cuproptosis-related genes.
63 cuproptosis-related genes
MT1M
cuproptosis
35964468 By LASSO and COX regressions, 13 prognosis-related cuproptosis genes were further selected and their HR was obtained.
cuproptosis-related genes
MT1M
cuproptosis
35964468 Cuproptosis-related gene sets were obtained from a previous study [9] and combined with the Molecular Signature Database (MsigDB) v7.0 database (http://www.gsea-msigdb.org/gsea/msigdb/, GOBP_CELLULAR_COPPER_ION_HOMEOSTASIS, GOBP_CELLULAR_RESPONSE_TO_COPPER_ION).
Cuproptosis-related gene sets obtained from Molecular Signature Database (MsigDB) v7.14 database.
MT1M
cuproptosis
36211378 Forty-three cuproptosis-related genes were selected from the review of Chang et al. (13)
43 cuproptosis-related genes in the study
Go Annotation:
GeneSymbol
Go id
MT1M
GO:0005515,GO:0005634,GO:0005634,GO:0005737,GO:0005737,GO:0006882,GO:0008270,GO:0010273,GO:0045926,GO:0046872,GO:0071276,GO:0071280,GO:0071294,GO:0071294
KEGG Annotation:
GeneSymbol
GeneID
Pathway
Pathway Name
MT1M
hsa:4499 path:hsa04978 Mineral absorption - Homo sapiens (human)
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
URS000003ABC4
MT1M
19088304
25416803
mrna cleavage,inhibition
array technology
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
KRTAP5-9
MT1M
24234451
25348397
physical association
two hybrid,two hybrid array,two hybrid prey pooling approach
ComPPI,IntAct
PAN2
MT1M
25348397
N/A
physical interaction
ComPPI
RELB
MT1M
21988832
24234451
25348397
physical association
two hybrid,physical interaction,two hybrid array
ComPPI,IntAct
Visualization
