Gene Information gene info

  1. Home

GENE：STEAP3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol STEAP3
FullNmae STEAP3 metalloreductase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24592
EnsembleID ENSG00000115107
Uniprot Q658P3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
STEAP3 mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
STEAP3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
STEAP3 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
STEAP3 ferroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
STEAP3 cuproptosis 38613350 First, a 10-cuproptosis-related gene signature (ADAM9, ADAM17, ALB, AQP1, CDK1, MT2A, PAM, SOD3, STEAP3, and TMPRSS6) displayed excellent predictive performance for the overall survival of cholangiocarcinoma. retulator signature

Go Annotation:

GeneSymbol Go id
STEAP3 GO:0005515,GO:0005737,GO:0005768,GO:0005771,GO:0005886,GO:0006915,GO:0007049,GO:0008823,GO:0009306,GO:0009306,GO:0010008,GO:0010008,GO:0015677,GO:0016723,GO:0020037,GO:0033572,GO:0034755,GO:0046872,GO:0052851,GO:0052851,GO:0071949

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
STEAP3 hsa:55240 path:hsa04115 p53 signaling pathway - Homo sapiens (human)
STEAP3 hsa:55240 path:hsa04216 Ferroptosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR STEAP3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 STEAP3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 STEAP3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 STEAP3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA STEAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF STEAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 STEAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 STEAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 STEAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A STEAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 STEAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 STEAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 STEAP3 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 STEAP3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000BD6DC STEAP3 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000009EA8F STEAP3 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001DA458 STEAP3 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000419B5A STEAP3 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075BC91 STEAP3 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C3AC1 STEAP3 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002F74F1 STEAP3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000512C88 STEAP3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000017CCCB STEAP3 23446348 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
BNIP3L STEAP3 25361965 interaction type N/A PTMCode2
STEAP3 BNIP3L 25361965 interaction type N/A PTMCode2
PKMYT1 STEAP3 25361965 interaction type N/A PTMCode2
STEAP3 PKMYT1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
DPEP1 STEAP3 25348397 N/A physical interaction ComPPI
BAD STEAP3 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CDH1 STEAP3 25348397 N/A physical interaction ComPPI
PTGIR STEAP3 25348397 N/A physical interaction ComPPI
TPT1 STEAP3 14525934 15319436 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD,OmniPath
SETD7 STEAP3 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ATP2B2 STEAP3 25348397 N/A physical interaction ComPPI
PKMYT1 STEAP3 12606722 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
TGOLN2 STEAP3 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
STEAP3 BNIP3L 12606722 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
STEAP3 BSG 25348397 N/A physical interaction ComPPI
STEAP3 TEX29 25348397 N/A physical interaction ComPPI
STEAP3 NT5E 25348397 N/A physical interaction ComPPI
STEAP3 SLC39A4 25348397 N/A physical interaction ComPPI
STEAP3 DLK1 25348397 N/A physical interaction ComPPI
STEAP3 TMEFF1 25348397 N/A physical interaction ComPPI
STEAP3 ENPP6 25348397 N/A physical interaction ComPPI
STEAP3 FAM177A1 25348397 N/A physical interaction ComPPI
STEAP3 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
STEAP3 TMEM216 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
STEAP3 ASPH 25348397 N/A physical interaction ComPPI
STEAP3 RANBP6 25348397 N/A physical interaction ComPPI
STEAP3 MRAP2 25348397 N/A physical interaction ComPPI
STEAP3 SCN3B 25348397 N/A physical interaction ComPPI
STEAP3 MBLAC2 25348397 N/A physical interaction ComPPI
STEAP3 TIGD5 25348397 N/A physical interaction ComPPI
STEAP3 CD83 25348397 N/A physical interaction ComPPI
STEAP3 TTC21A 24234451 25348397 27173435 physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
STEAP3 BET1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
STEAP3 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TP53 STEAP3 18431400 27898060 stimulant N/A OmniPath

Visualization










  Return