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GENE：BCL2L10

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol BCL2L10
FullNmae BCL2 like 10
LocusType gene with protein product
Status Approved
HGNC_id HGNC:993
EnsembleID ENSG00000137875
Uniprot Q9HD36

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
BCL2L10 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BCL2L10 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BCL2L10 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
BCL2L10 GO:0005509,GO:0005515,GO:0005739,GO:0005741,GO:0005783,GO:0005819,GO:0005829,GO:0006915,GO:0006919,GO:0007283,GO:0007292,GO:0008630,GO:0016020,GO:0031023,GO:0031965,GO:0042803,GO:0043066,GO:0044233,GO:0046982,GO:0089720,GO:0097192

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR BCL2L10 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 BCL2L10 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 BCL2L10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA BCL2L10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 BCL2L10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS BCL2L10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF BCL2L10 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000035CC3E BCL2L10 24184144 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
BCL2L10 BAX 25361965 interaction type N/A PTMCode2
BAX BCL2L10 25361965 interaction type N/A PTMCode2
BCL2L10 BCL2L1 25361965 interaction type N/A PTMCode2
BCL2L1 BCL2L10 25361965 interaction type N/A PTMCode2
BCL2L10 BCL2 25361965 interaction type N/A PTMCode2
BCL2 BCL2L10 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
BCL2L11 BCL2L10 23235460 24234451 25348397 physical association circular dichroism,dynamic light scattering,molecular sieving,surface plasmon resonance,x-ray crystallography ComPPI,IntAct
BIK BCL2L10 23235460 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
BCL2L1 BCL2L10 11278245 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
BAD BCL2L10 11278245 14525934 25348397 9878060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CASP8 BCL2L10 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NR4A1 BCL2L10 14525934 18835031 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
BAK1 BCL2L10 14525934 25348397 9878060 N/A experimental interaction detection,in vivo ComPPI,HPRD
BCL2 BCL2L10 11278245 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
APAF1 BCL2L10 10486928 14525934 25348397 27898060 9829980 9878060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
BCL2L10 BAX 11278245 14525934 23235460 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
BCL2L10 UBQLN1 25348397 N/A physical interaction ComPPI
BCL2L10 BCL2L10 14525934 9878060 N/A experimental interaction detection HPRD

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