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GENE：FKBP4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FKBP4
FullNmae FKBP prolyl isomerase 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3720
EnsembleID ENSG00000004478
Uniprot Q02790

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FKBP4 cuproptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FKBP4 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FKBP4 GO:0000413,GO:0003723,GO:0003755,GO:0003755,GO:0005515,GO:0005524,GO:0005525,GO:0005528,GO:0005654,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0005829,GO:0005829,GO:0005874,GO:0006457,GO:0006463,GO:0006825,GO:0007566,GO:0010977,GO:0030521,GO:0030674,GO:0030850,GO:0031072,GO:0031111,GO:0031115,GO:0031503,GO:0032767,GO:0032991,GO:0035259,GO:0043025,GO:0044295,GO:0046661,GO:0048156,GO:0048471,GO:0051219,GO:0061077,GO:0061077,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FKBP4 hsa:2288 path:hsa04915 Estrogen signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FKBP4 IRF4 10714679 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
IKBKB FKBP4 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK3 FKBP4 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 FKBP4 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 FKBP4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 FKBP4 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 FKBP4 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 FKBP4 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C FKBP4 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 FKBP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FKBP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 FKBP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 FKBP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FKBP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A FKBP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 FKBP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
AR FKBP4 23192983 trascriptional regulation,stimulation inferred by curator TFlink
HSF1 FKBP4 20692357 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000512C88 FKBP4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000070B1D FKBP4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EC1BE FKBP4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000BE495 FKBP4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C308D FKBP4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 FKBP4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A7F58 FKBP4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000035CC3E FKBP4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE FKBP4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005FDE70 FKBP4 23622248 25416803 28026009 mrna cleavage,inhibition array technology,nucleotide sequence identification,clash TarBase
URS00001C770D FKBP4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000F4AC3 FKBP4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001CC864 FKBP4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000458AD2 FKBP4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000057FDB8 FKBP4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075B0F6 FKBP4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000023F008 FKBP4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002CBC6D FKBP4 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
FKBP4 NR3C1 25361965 interaction type N/A PTMCode2
NR3C1 FKBP4 25361965 interaction type N/A PTMCode2
FKBP4 PHYH 25361965 interaction type N/A PTMCode2
PHYH FKBP4 25361965 interaction type N/A PTMCode2
FKBP4 STIP1 25361965 interaction type N/A PTMCode2
STIP1 FKBP4 25361965 interaction type N/A PTMCode2
FKBP4 PTPN2 25361965 interaction type N/A PTMCode2
PTPN2 FKBP4 25361965 interaction type N/A PTMCode2
FKBP4 ATOX1 25361965 interaction type N/A PTMCode2
ATOX1 FKBP4 25361965 interaction type N/A PTMCode2
FKBP4 HSP90AA1 25361965 interaction type N/A PTMCode2
HSP90AA1 FKBP4 25361965 interaction type N/A PTMCode2
FKBP4 FKBP5 25361965 interaction type N/A PTMCode2
FKBP5 FKBP4 25361965 interaction type N/A PTMCode2
FKBP4 S100A6 25361965 interaction type N/A PTMCode2
S100A6 FKBP4 25361965 interaction type N/A PTMCode2
FKBP4 GLMN 25361965 interaction type N/A PTMCode2
GLMN FKBP4 25361965 interaction type N/A PTMCode2
FKBP4 IRF4 25361965 interaction type N/A PTMCode2
IRF4 FKBP4 25361965 interaction type N/A PTMCode2
FKBP4 FKBP4 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDC73 FKBP4 25348397 N/A physical interaction ComPPI
S100A1 FKBP4 25348397 N/A physical interaction ComPPI
S100A2 FKBP4 20188096 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction,competition binding ComPPI,IntAct
LCA5 FKBP4 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TAF9 FKBP4 25348397 N/A physical interaction ComPPI
NUDCD3 FKBP4 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
CALM1 FKBP4 25348397 N/A physical interaction ComPPI
FKBP1A FKBP4 11164950 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
KEAP1 FKBP4 25348397 N/A physical interaction ComPPI
MCM2 FKBP4 25348397 N/A physical interaction ComPPI
HSP90AB1 FKBP4 21170051 21730179 24234451 25036637 25348397 27898060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,cosedimentation in solution,physical interaction ComPPI,IntAct,OmniPath
CDC37L1 FKBP4 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LSM7 FKBP4 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMURF2 FKBP4 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
JUN FKBP4 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
AR FKBP4 21730179 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
IRF4 FKBP4 10714679 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
YWHAZ FKBP4 15161933 24234451 25348397 physical association pull down ComPPI,IntAct
FES FKBP4 25348397 N/A physical interaction ComPPI
HSP90AA1 FKBP4 10642522 19875381 20188096 20661446 21170051 21360678 22678819 22863883 24234451 25036637 25348397 27898060 8662874 association anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification ComPPI,IntAct,OmniPath
NTRK1 FKBP4 25348397 N/A physical interaction ComPPI
PTPN2 FKBP4 25348397 N/A in vitro ComPPI
STIP1 FKBP4 21170051 24234451 25348397 physical association cosedimentation in solution,physical interaction ComPPI,IntAct
IKBKB FKBP4 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PTGES3 FKBP4 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MAPT FKBP4 20133804 25348397 27898060 N/A far western blotting,physical interaction ComPPI,OmniPath
CSNK2A1 FKBP4 14525934 25348397 9405642 N/A experimental interaction detection,in vitro ComPPI,HPRD
CACYBP FKBP4 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NPHP1 FKBP4 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SQSTM1 FKBP4 25348397 N/A physical interaction ComPPI
EWSR1 FKBP4 25348397 N/A physical interaction ComPPI
TPM3 FKBP4 25348397 N/A physical interaction ComPPI
SAE1 FKBP4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2 FKBP4 25348397 N/A physical interaction ComPPI
EGFR FKBP4 20029029 24234451 25348397 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
GLMN FKBP4 10051602 11164950 12604780 14525934 24234451 25036637 25348397 27898060 8955134 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach ComPPI,HPRD,IntAct,OmniPath
FKBP4 NR3C2 14525934 25348397 9392437 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
FKBP4 PHYH 10051602 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
FKBP4 ACVR1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FKBP4 NR3C1 14525934 20661446 25348397 27898060 8341706 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
FKBP4 LOXHD1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP4 ESR1 25348397 N/A physical interaction ComPPI
FKBP4 HSF1 25348397 N/A physical interaction ComPPI
FKBP4 ATG101 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP4 FOXO3 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP4 GABARAP 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP4 NIPSNAP2 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP4 PIK3C2A 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP4 PRKAG1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP4 PRKAG2 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP4 SH3GLB2 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP4 UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP4 HSP90AA2P 25348397 N/A physical interaction ComPPI
FKBP4 RIPK3 25348397 N/A physical interaction ComPPI
FKBP4 SH3BP4 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FKBP4 SIRT7 25348397 N/A physical interaction ComPPI
FKBP4 PGR 25348397 N/A physical interaction ComPPI
FKBP4 SNCA 25348397 N/A physical interaction ComPPI
FKBP4 SARDH 25348397 N/A physical interaction ComPPI
FKBP4 AK6 25348397 N/A physical interaction ComPPI
FKBP4 VCAM1 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
FKBP4 MCM3 25348397 N/A physical interaction ComPPI
FKBP4 MCM4 25348397 N/A physical interaction ComPPI
FKBP4 OGA 25348397 N/A physical interaction ComPPI
FKBP4 AHSA1 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP4 CDC37 24234451 25036637 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction,luminescence based mammalian interactome mapping ComPPI,IntAct
FKBP4 CHORDC1 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP4 SUGT1 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP4 USP19 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP4 CUL7 25348397 N/A physical interaction ComPPI
FKBP4 HSPA4 25348397 N/A physical interaction ComPPI
FKBP4 HSPB1 24234451 25277244 25348397 physical association anti bait coimmunoprecipitation,reverse ras recruitment system,physical interaction ComPPI,IntAct
FKBP4 FBXW11 25348397 N/A physical interaction ComPPI
FKBP4 PLS1 25348397 N/A physical interaction ComPPI
FKBP4 PRKAB1 25348397 N/A physical interaction ComPPI
FKBP4 CEP290 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP4 OFD1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
FKBP4 MKS1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
FKBP4 NPHP4 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
FKBP4 POC1A 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
FKBP4 RPGR 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
FKBP4 STIL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
FKBP4 EGLN1 25348397 N/A physical interaction ComPPI
FKBP4 PHLPP1 25348397 N/A physical interaction ComPPI
FKBP4 PPEF2 25348397 N/A physical interaction ComPPI
FKBP4 MGME1 25348397 N/A physical interaction ComPPI
FKBP4 NPB 25348397 N/A physical interaction ComPPI
FKBP4 BRCA1 25348397 N/A physical interaction ComPPI
FKBP4 AGO2 23741051 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
FKBP4 OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
FKBP4 CHEK2 23178491 24234451 25348397 association tandem affinity purification ComPPI,IntAct
FKBP4 PHOSPHO1 24234451 25348397 28330616 association pull down ComPPI,IntAct
ATOX1 FKBP4 14525934 15133031 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
S100A6 FKBP4 20188096 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction,competition binding ComPPI,IntAct
NEK8 FKBP4 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
DDA1 FKBP4 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP4 TRPC1 15199065 19945390 23228564 27898060 inhibition N/A OmniPath
FKBP4 TRPV5 16352746 27898060 inhibition N/A OmniPath
PTPN2 FKBP4 12552015 15509512 27898060 inhibition N/A OmniPath
IKBKB FKBP4 21903422 27898060 N/A N/A OmniPath
IL15 FKBP4 21903422 27898060 N/A N/A OmniPath

Visualization










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