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GENE：CDK5RAP3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CDK5RAP3
FullNmae CDK5 regulatory subunit associated protein 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18673
EnsembleID ENSG00000108465
Uniprot Q96JB5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CDK5RAP3 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CDK5RAP3 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CDK5RAP3 GO:0000079,GO:0000079,GO:0001889,GO:0001933,GO:0005515,GO:0005634,GO:0005730,GO:0005737,GO:0005813,GO:0005829,GO:0005874,GO:0007095,GO:0007346,GO:0007420,GO:0008283,GO:0010921,GO:0016020,GO:0019901,GO:0019901,GO:0030262,GO:0030332,GO:0030968,GO:0031398,GO:0032088,GO:0032991,GO:0034976,GO:0042177,GO:0043231,GO:0043407,GO:0044387,GO:0044389,GO:0044818,GO:0045664,GO:0045944,GO:0051019,GO:0051059,GO:0060318,GO:0071569,GO:0071569,GO:0071901,GO:0097371,GO:1900182,GO:1901798

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 CDK5RAP3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 CDK5RAP3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 CDK5RAP3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CDK5RAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CDK5RAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CDK5RAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CDK5RAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CDK5RAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CDK5RAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CDK5RAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CDK5RAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CDK5RAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 CDK5RAP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 CDK5RAP3 N/A rna interference,inhibition experimental interaction detection miRSponge
URS0000338542 CDK5RAP3 18668040 20584899 25416803 mrna cleavage,inhibition experimental interaction detection TarBase

Source Target Pmid Interactiontype Methods Database
CDK5R1 CDK5RAP3 25361965 interaction type N/A PTMCode2
CDK5RAP3 CDK5R1 25361965 interaction type N/A PTMCode2
CDK5RAP3 RELA 25361965 interaction type N/A PTMCode2
RELA CDK5RAP3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KPNA2 CDK5RAP3 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HSPA8 CDK5RAP3 25348397 N/A physical interaction ComPPI
TSPYL4 CDK5RAP3 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TAX1BP3 CDK5RAP3 25348397 N/A physical interaction ComPPI
NPM1 CDK5RAP3 25348397 N/A physical interaction ComPPI
CDK5R1 CDK5RAP3 10721722 10915792 11882646 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
CDK5RAP3 CREBBP 14525934 16012757 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
CDK5RAP3 CRMP1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CDK5RAP3 SRPRB 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
CDK5RAP3 UFM1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK5RAP3 UFC1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK5RAP3 DDRGK1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK5RAP3 SMNDC1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK5RAP3 KHK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK5RAP3 UFL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CDK5RAP3 ARL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK5RAP3 LYPD6B 25348397 N/A physical interaction ComPPI
CDK5RAP3 HSPA4 25348397 N/A physical interaction ComPPI
CDK5RAP3 UBC 25348397 N/A physical interaction ComPPI
CDK5RAP3 HUWE1 25348397 N/A physical interaction ComPPI
CDK5RAP3 RPL10A 25348397 N/A physical interaction ComPPI
CDK5RAP3 PIP4P2 25348397 N/A physical interaction ComPPI
CDK5RAP3 RPS3 25348397 N/A physical interaction ComPPI
CDK5RAP3 MME 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
CDK5RAP3 CDH4 25348397 N/A physical interaction ComPPI
CDK5RAP3 DISC1 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CDK5RAP3 CDKN2A 25348397 N/A physical interaction ComPPI
CDK5RAP3 CDKN2A 25348397 N/A physical interaction ComPPI
CDK5RAP3 MDM2 25348397 N/A physical interaction ComPPI
CDK5RAP3 TUBG1 21465471 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CDK5RAP3 TAB1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CDK5RAP3 ESS2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CDK5RAP3 FKBP6 24234451 25348397 25416956 25910212 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
CDK5RAP3 CD274 25348397 N/A physical interaction ComPPI
CDK5RAP3 HSPB1 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
CDK5RAP3 TMED4 25348397 N/A physical interaction ComPPI
CDK5RAP3 PLD2 25348397 N/A physical interaction ComPPI
CDK5RAP3 TMED1 25348397 N/A physical interaction ComPPI
CDK5RAP3 PACC1 25348397 N/A physical interaction ComPPI
CDK5RAP3 SIGLECL1 25348397 N/A physical interaction ComPPI
CDK5RAP3 TMED9 25348397 N/A physical interaction ComPPI
CDK5RAP3 TPTE2 25348397 N/A physical interaction ComPPI
CDK5RAP3 MRPS7 25348397 N/A physical interaction ComPPI
CDK5RAP3 UPF3A 25348397 N/A physical interaction ComPPI
CDK5RAP3 AMTN 25348397 N/A physical interaction ComPPI
CDK5RAP3 PRKAB1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CDK5RAP3 BANF1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CDK5RAP3 IGHA1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CDK5RAP3 IGKC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CDK5RAP3 LTF 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CDK5RAP3 OTUD4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CDK5RAP3 DHX36 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CDK5RAP3 WWC3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CDK5RAP3 RPL36 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CDK5RAP3 DMBT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CDK5RAP3 RELA 17785205 24234451 25348397 physical association anti bait coimmunoprecipitation,pull down ComPPI,IntAct
CDK5RAP3 CANX 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CDK5RAP3 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
JUP CDK5RAP3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TRIM44 CDK5RAP3 25348397 N/A physical interaction ComPPI
HSCB CDK5RAP3 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
MKI67 CDK5RAP3 24234451 26949251 association anti tag coimmunoprecipitation IntAct
CDK5RAP3 CHEK1 19223857 27898060 inhibition N/A OmniPath
CDK5RAP3 CDK1 19223857 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B6F5B CDK5RAP3 27087310 direct interaction,inhibition N/A NPInter

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