GENE:CLSPN
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | CLSPN |
FullNmae | claspin |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:19715 |
EnsembleID | ENSG00000092853 |
Uniprot | Q9HAW4 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
CLSPN | parthanatos | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
CLSPN | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
CLSPN | GO:0000076,GO:0000077,GO:0000217,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005794,GO:0006281,GO:0007095,GO:0007095,GO:0010997,GO:0010997,GO:0018105,GO:0032147,GO:0032147,GO:0033314,GO:0033314 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ETS1 | CLSPN | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
YBX1 | CLSPN | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
SMARCA4 | CLSPN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | CLSPN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | CLSPN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | CLSPN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | CLSPN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
GATA2 | CLSPN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | CLSPN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TAL1 | CLSPN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
ZNF263 | CLSPN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000521626 | CLSPN | 17612493 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00003380CC | CLSPN | 17612493 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000F31F4 | CLSPN | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000B59A2 | CLSPN | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000BE495 | CLSPN | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00003D5391 | CLSPN | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00000C85B2 | CLSPN | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS0000065FDF | CLSPN | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075A760 | CLSPN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002152A8 | CLSPN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000023F008 | CLSPN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001C770D | CLSPN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000AB32B | CLSPN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004F2EB0 | CLSPN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001496AE | CLSPN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002E1509 | CLSPN | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000007D64A | CLSPN | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000F0F49 | CLSPN | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000040EE1D | CLSPN | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000041CB9C | CLSPN | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000171CD1 | CLSPN | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002E628F | CLSPN | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000032FC1A | CLSPN | 20371350 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
URS00005C1F22 | CLSPN | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000C5BAA | CLSPN | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000076995 | CLSPN | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000003575B | CLSPN | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00005D986D | CLSPN | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000508C13 | CLSPN | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000045DBD | CLSPN | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000035AC91 | CLSPN | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
URS00002FF522 | CLSPN | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
URS000075C1E1 | CLSPN | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
URS00004E008F | CLSPN | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
CHEK1 | CLSPN | 22135298 | phosphorylation | N/A | PhosphoSite |
CDC7 | CLSPN | 22135298 | phosphorylation | N/A | PhosphoSite |
PLK1 | CLSPN | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
CLSPN | PLK1 | 25361965 | interaction type | N/A | PTMCode2 |
RAD9A | CLSPN | 25361965 | interaction type | N/A | PTMCode2 |
CLSPN | RAD9A | 25361965 | interaction type | N/A | PTMCode2 |
USP28 | CLSPN | 25361965 | interaction type | N/A | PTMCode2 |
CLSPN | USP28 | 25361965 | interaction type | N/A | PTMCode2 |
CASP7 | CLSPN | 25361965 | interaction type | N/A | PTMCode2 |
CLSPN | CASP7 | 25361965 | interaction type | N/A | PTMCode2 |
CLSPN | USP7 | 25361965 | interaction type | N/A | PTMCode2 |
USP7 | CLSPN | 25361965 | interaction type | N/A | PTMCode2 |
CLSPN | ATR | 25361965 | interaction type | N/A | PTMCode2 |
ATR | CLSPN | 25361965 | interaction type | N/A | PTMCode2 |
CLSPN | BRCA1 | 25361965 | interaction type | N/A | PTMCode2 |
BRCA1 | CLSPN | 25361965 | interaction type | N/A | PTMCode2 |
CLSPN | BTRC | 25361965 | interaction type | N/A | PTMCode2 |
BTRC | CLSPN | 25361965 | interaction type | N/A | PTMCode2 |
CLSPN | PCNA | 25361965 | interaction type | N/A | PTMCode2 |
PCNA | CLSPN | 25361965 | interaction type | N/A | PTMCode2 |
CLSPN | RAD17 | 25361965 | interaction type | N/A | PTMCode2 |
RAD17 | CLSPN | 25361965 | interaction type | N/A | PTMCode2 |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
USP20 | CLSPN | 25348397 | N/A | physical interaction | ComPPI |
PCNA | CLSPN | 25348397 | N/A | physical interaction | ComPPI |
MYH7 | CLSPN | 25348397 | N/A | physical interaction | ComPPI |
EGLN3 | CLSPN | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
ATR | CLSPN | 12766152 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
USP7 | CLSPN | 25348397 | N/A | physical interaction | ComPPI |
FZR1 | CLSPN | 18662541 24234451 25348397 | physical association | anti tag coimmunoprecipitation,pull down,physical interaction | ComPPI,IntAct |
BTRC | CLSPN | 25348397 | N/A | physical interaction | ComPPI |
RPA1 | CLSPN | 24126761 24234451 25348397 | association | tandem affinity purification | ComPPI,IntAct |
RAD9A | CLSPN | 12766152 14525934 20424596 24234451 25348397 | physical association | anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
MSH6 | CLSPN | 25348397 | N/A | physical interaction | ComPPI |
PLK1 | CLSPN | 25348397 | N/A | physical interaction | ComPPI |
CASP7 | CLSPN | 14525934 16123041 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
XPO1 | CLSPN | 25348397 | N/A | physical interaction | ComPPI |
RPA2 | CLSPN | 24126761 24234451 25348397 | association | tandem affinity purification | ComPPI,IntAct |
RPA3 | CLSPN | 24126761 24234451 25348397 | association | tandem affinity purification | ComPPI,IntAct |
CHEK1 | CLSPN | 12766152 14525934 16123041 16963448 24234451 25348397 | phosphorylation reaction,physical association | anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,protein kinase assay,in vitro,in vivo | ComPPI,HPRD,IntAct |
CDC20 | CLSPN | 25348397 | N/A | physical interaction | ComPPI |
CDK9 | CLSPN | 20930849 24234451 25348397 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CDC45 | CLSPN | 23910567 24234451 25348397 | association,physical association | anti bait coimmunoprecipitation,pull down | ComPPI,IntAct |
CDC7 | CLSPN | 25348397 | N/A | physical interaction | ComPPI |
MPP1 | CLSPN | 25348397 | N/A | physical interaction | ComPPI |
RAD17 | CLSPN | 25348397 | N/A | physical interaction | ComPPI |
BRCA1 | CLSPN | 14525934 15096610 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
CLSPN | USP28 | 14525934 16901786 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
CLSPN | TIMELESS | 25348397 | N/A | physical interaction | ComPPI |
CLSPN | FBXW11 | 25348397 | N/A | physical interaction | ComPPI |
CLSPN | PMS2 | 25348397 | N/A | physical interaction | ComPPI |
CLSPN | PMS2CL | 25348397 | N/A | physical interaction | ComPPI |
CLSPN | LTA | 25348397 | N/A | physical interaction | ComPPI |
CLSPN | HERC2 | 25348397 | N/A | physical interaction | ComPPI |
CLSPN | HERC2P3 | 25348397 | N/A | physical interaction | ComPPI |
CLSPN | USP29 | 25348397 | N/A | physical interaction | ComPPI |
CLSPN | CEP250 | 25348397 | N/A | physical interaction | ComPPI |
CLSPN | GINS3 | 25348397 | N/A | physical interaction | ComPPI |
CLSPN | GJB2 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CLSPN | LTN1 | 25348397 | N/A | physical interaction | ComPPI |
CLSPN | PRIMPOL | 24126761 24234451 25348397 | association | tandem affinity purification | ComPPI,IntAct |
CASP3 | CLSPN | 17431426 27898060 | N/A | N/A | OmniPath |
PLK1 | CLSPN | 15163406 16885021 16885022 27898060 | inhibition,stimulant | N/A | OmniPath |
CHEK1 | CLSPN | 11090622 12766152 15279790 15371427 16123041 16963448 18451105 23109433 27898060 | stimulant | N/A | OmniPath |
CLSPN | CHEK1 | 11090622 12766152 15279790 15371427 16123041 16963448 18451105 23109433 27898060 | inhibition,stimulant | N/A | OmniPath |
USP28 | CLSPN | 16901786 19680264 27898060 | inhibition,stimulant | N/A | OmniPath |
ATR | CLSPN | 12766152 18077418 18309293 27898060 | inhibition | N/A | OmniPath |
CLSPN | UBE2B | 18451105 27898060 | stimulant | N/A | OmniPath |
E2F4 | CLSPN | 17251008 18319725 27898060 | inhibition | N/A | OmniPath |
USP7 | CLSPN | 19124652 19680264 19706760 27898060 | stimulant | N/A | OmniPath |
CDC7 | CLSPN | 18084324 23598722 27898060 | N/A | N/A | OmniPath |
FBXW11 | CLSPN | 16885021 16885022 18662541 22017875 25332235 25515538 27898060 | inhibition | N/A | OmniPath |
PI4K2A | CLSPN | 18082599 27898060 | inhibition | N/A | OmniPath |