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GENE：ARIH1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ARIH1
FullNmae ariadne RBR E3 ubiquitin protein ligase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:689
EnsembleID ENSG00000166233
Uniprot Q9Y4X5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ARIH1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ARIH1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ARIH1 GO:0000151,GO:0000151,GO:0000209,GO:0004842,GO:0004842,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0006511,GO:0006511,GO:0008270,GO:0015030,GO:0016567,GO:0016567,GO:0016604,GO:0019787,GO:0031624,GO:0031624,GO:0031625,GO:0032436,GO:0061630,GO:0097413

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ARIH1 hsa:25820 path:hsa04137 Mitophagy - animal - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EIF4E2 ARIH1 17289916 29145629 physical association inferred by curator Reactome
EIF4G3 ARIH1 17289916 29145629 physical association inferred by curator Reactome
EIF4E ARIH1 17289916 29145629 physical association inferred by curator Reactome
EIF4G2 ARIH1 17289916 29145629 physical association inferred by curator Reactome
EIF4A2 ARIH1 17289916 29145629 physical association inferred by curator Reactome
EIF4E3 ARIH1 17289916 29145629 physical association inferred by curator Reactome
EIF4A1 ARIH1 17289916 29145629 physical association inferred by curator Reactome
FLNB ARIH1 12582176 16009940 19270716 29145629 physical association inferred by curator Reactome
PPM1B ARIH1 16872604 29145629 physical association inferred by curator Reactome

Source Target Pmid Interactiontype Methods Database
AR ARIH1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ARIH1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ARIH1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 ARIH1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ARIH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ARIH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ARIH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ARIH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ARIH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ARIH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 ARIH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 ARIH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ARIH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 ARIH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000048BA36 ARIH1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA ARIH1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000171CD1 ARIH1 20371350 21572407 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C ARIH1 20371350 21572407 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D ARIH1 20371350 21572407 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 ARIH1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A ARIH1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 ARIH1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 ARIH1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C ARIH1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF ARIH1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000008F0CF ARIH1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 ARIH1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000058878F ARIH1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075BEA7 ARIH1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000017DBB8 ARIH1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000001A7A ARIH1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000009EA8F ARIH1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000BD6DC ARIH1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000015A0D9 ARIH1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002394F5 ARIH1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075A608 ARIH1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000ECE9C ARIH1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004E02F2 ARIH1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000004BACE ARIH1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00006097A6 ARIH1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002367FA ARIH1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075A611 ARIH1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001481F9 ARIH1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 ARIH1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 ARIH1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00000292B1 ARIH1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000482389 ARIH1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC4BD ARIH1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 ARIH1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003676C9 ARIH1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003BD367 ARIH1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 ARIH1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000032EF64 ARIH1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000237CBD ARIH1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000029979D ARIH1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000000B1C9 ARIH1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000A07C1 ARIH1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 ARIH1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 ARIH1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005E1A16 ARIH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000140295 ARIH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEE35 ARIH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C ARIH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000610EFA ARIH1 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
FBXW11 ARIH1 25361965 interaction type N/A PTMCode2
ARIH1 FBXW11 25361965 interaction type N/A PTMCode2
UBE2L6 ARIH1 25361965 interaction type N/A PTMCode2
ARIH1 UBE2L6 25361965 interaction type N/A PTMCode2
UBE2L3 ARIH1 25361965 interaction type N/A PTMCode2
ARIH1 UBE2L3 25361965 interaction type N/A PTMCode2
EIF4E2 ARIH1 25361965 interaction type N/A PTMCode2
ARIH1 EIF4E2 25361965 interaction type N/A PTMCode2
BRAP ARIH1 25361965 interaction type N/A PTMCode2
ARIH1 BRAP 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HOXB9 ARIH1 25348397 N/A physical interaction ComPPI
KCTD9 ARIH1 25348397 N/A physical interaction ComPPI
TNFAIP3 ARIH1 25348397 N/A physical interaction ComPPI
CDKN1B ARIH1 24076655 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
VCP ARIH1 25348397 N/A physical interaction ComPPI
DR1 ARIH1 25348397 N/A physical interaction ComPPI
UBE2D1 ARIH1 25348397 N/A physical interaction ComPPI
JUNB ARIH1 25348397 N/A physical interaction ComPPI
PEF1 ARIH1 25348397 N/A physical interaction ComPPI
KBTBD7 ARIH1 25348397 N/A physical interaction ComPPI
KCTD13 ARIH1 25348397 N/A physical interaction ComPPI
UBE2E2 ARIH1 25348397 N/A physical interaction ComPPI
VAV2 ARIH1 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NOTCH1 ARIH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
JUN ARIH1 24234451 25348397 25609649 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CREB5 ARIH1 25348397 N/A physical interaction ComPPI
JUND ARIH1 25348397 N/A physical interaction ComPPI
UBE2L3 ARIH1 10521492 11278816 14525934 24076655 24234451 25348397 association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,isothermal titration calorimetry,molecular sieving,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
CUL3 ARIH1 24076655 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBB ARIH1 25348397 N/A physical interaction,comigration in sds page ComPPI
UBC ARIH1 25348397 N/A physical interaction,comigration in sds page ComPPI
RPS27A ARIH1 25348397 N/A physical interaction,comigration in sds page ComPPI
UBA52 ARIH1 25348397 N/A physical interaction,comigration in sds page ComPPI
UBE2N ARIH1 25348397 N/A physical interaction ComPPI
P3H1 ARIH1 25348397 N/A physical interaction ComPPI
BTRC ARIH1 25348397 N/A physical interaction ComPPI
XPO5 ARIH1 25348397 N/A physical interaction ComPPI
TNFAIP1 ARIH1 25348397 N/A physical interaction ComPPI
HNRNPL ARIH1 25348397 N/A physical interaction ComPPI
CCN2 ARIH1 25348397 N/A physical interaction ComPPI
CASK ARIH1 25348397 N/A physical interaction ComPPI
ECT2 ARIH1 25348397 N/A physical interaction ComPPI
ISL1 ARIH1 25348397 N/A physical interaction ComPPI
EPN3 ARIH1 25348397 N/A physical interaction ComPPI
UBA2 ARIH1 25348397 N/A physical interaction ComPPI
NEDD8 ARIH1 25348397 N/A physical interaction ComPPI
CUL2 ARIH1 24076655 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL1 ARIH1 24076655 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL4A ARIH1 24076655 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPB1 ARIH1 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
SNCAIP ARIH1 25348397 N/A physical interaction ComPPI
SETD7 ARIH1 25348397 N/A physical interaction ComPPI
SHKBP1 ARIH1 25348397 N/A physical interaction ComPPI
PRKN ARIH1 25348397 N/A physical interaction ComPPI
UBE2D3 ARIH1 25348397 N/A physical interaction ComPPI
DHPS ARIH1 25348397 N/A physical interaction ComPPI
ISL2 ARIH1 25348397 N/A physical interaction ComPPI
TRIM25 ARIH1 25348397 N/A physical interaction ComPPI
UBE2L6 ARIH1 10521492 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
PIP5K1A ARIH1 25348397 N/A physical interaction ComPPI
GOPC ARIH1 25348397 N/A physical interaction ComPPI
SPOP ARIH1 25348397 N/A physical interaction ComPPI
BRCA1 ARIH1 25348397 N/A physical interaction ComPPI
ATF1 ARIH1 25348397 N/A physical interaction ComPPI
FBXL5 ARIH1 25348397 N/A physical interaction ComPPI
FBXW2 ARIH1 25348397 N/A physical interaction ComPPI
ATF7 ARIH1 25348397 N/A physical interaction ComPPI
ELAC2 ARIH1 25348397 N/A physical interaction ComPPI
ARIH1 EIF4E2 14525934 14623119 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
ARIH1 FBXW11 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARIH1 SIM2 25348397 N/A physical interaction ComPPI
ARIH1 FBXO6 25348397 N/A physical interaction ComPPI
ARIH1 ANKMY2 25348397 N/A physical interaction ComPPI
ARIH1 BTF3L4 25348397 N/A physical interaction ComPPI
ARIH1 CTSC 25348397 N/A physical interaction ComPPI
ARIH1 WDR4 25348397 N/A physical interaction ComPPI
ARIH1 ZPR1 25348397 N/A physical interaction ComPPI
ARIH1 ZNF501 25348397 N/A physical interaction ComPPI
ARIH1 FBXL15 25348397 N/A physical interaction ComPPI
ARIH1 HAUS7 25348397 N/A physical interaction ComPPI
ARIH1 SPANXN3 25348397 N/A physical interaction ComPPI
ARIH1 ZFP41 25348397 N/A physical interaction ComPPI
ARIH1 SELENOH 25348397 N/A physical interaction ComPPI
ARIH1 CRAMP1 25348397 N/A physical interaction ComPPI
ARIH1 TULP3 25348397 N/A physical interaction ComPPI
ARIH1 ZNF852 25348397 N/A physical interaction ComPPI
ARIH1 PUS7L 25348397 N/A physical interaction ComPPI
ARIH1 UHRF1 25348397 N/A physical interaction ComPPI
ARIH1 KLHL7 25348397 N/A physical interaction ComPPI
ARIH1 TCEANC2 25348397 N/A physical interaction ComPPI
ARIH1 PLCD3 25348397 N/A physical interaction ComPPI
ARIH1 RHOBTB2 25348397 N/A physical interaction ComPPI
ARIH1 KATNA1 25348397 N/A physical interaction ComPPI
ARIH1 DDX47 25348397 N/A physical interaction ComPPI
ARIH1 TEFM 25348397 N/A physical interaction ComPPI
ARIH1 IRF9 25348397 N/A physical interaction ComPPI
ARIH1 KCTD10 25348397 N/A physical interaction ComPPI
ARIH1 ZNF687 25348397 N/A physical interaction ComPPI
ARIH1 MAGEE2 25348397 N/A physical interaction ComPPI
ARIH1 KLHDC2 25348397 N/A physical interaction ComPPI
ARIH1 CREB1 25348397 N/A physical interaction ComPPI
ARIH1 PDCD2L 25348397 N/A physical interaction ComPPI
ARIH1 KLHDC3 25348397 N/A physical interaction ComPPI
ARIH1 BBX 25348397 N/A physical interaction ComPPI
ARIH1 CAMKV 25348397 N/A physical interaction ComPPI
ARIH1 ZNF35 25348397 N/A physical interaction ComPPI
ARIH1 KBTBD6 25348397 N/A physical interaction ComPPI
ARIH1 THYN1 25348397 N/A physical interaction ComPPI
ARIH1 HOXA10 25348397 N/A physical interaction ComPPI
ARIH1 KCTD3 25348397 N/A physical interaction ComPPI
ARIH1 RNF138 25348397 N/A physical interaction ComPPI
ARIH1 PRPF31 25348397 N/A physical interaction ComPPI
ARIH1 RBM42 25348397 N/A physical interaction ComPPI
ARIH1 SRBD1 25348397 N/A physical interaction ComPPI
ARIH1 CCNE1 24076655 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
ATF2 ARIH1 25348397 N/A physical interaction ComPPI
ZNF263 ARIH1 25348397 N/A physical interaction ComPPI
BATF3 ARIH1 25348397 N/A physical interaction ComPPI
HOXC9 ARIH1 25348397 N/A physical interaction ComPPI
TGIF2LY ARIH1 25348397 N/A physical interaction ComPPI
ARIH1 PLD1 10926929 14525934 N/A two hybrid HPRD

Visualization










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