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GENE：ARPC1B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ARPC1B
FullNmae actin related protein 2/3 complex subunit 1B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:704
EnsembleID ENSG00000130429
Uniprot O15143

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ARPC1B pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ARPC1B autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ARPC1B GO:0005200,GO:0005515,GO:0005634,GO:0005829,GO:0005885,GO:0005885,GO:0005925,GO:0015629,GO:0032355,GO:0034314,GO:0034314,GO:0036284,GO:0043627,GO:0051015,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ARPC1B hsa:10095 path:hsa04144 Endocytosis - Homo sapiens (human)
ARPC1B hsa:10095 path:hsa04530 Tight junction - Homo sapiens (human)
ARPC1B hsa:10095 path:hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human)
ARPC1B hsa:10095 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
ARPC1B hsa:10095 path:hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human)
ARPC1B hsa:10095 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
ARPC1B hsa:10095 path:hsa05131 Shigellosis - Homo sapiens (human)
ARPC1B hsa:10095 path:hsa05132 Salmonella infection - Homo sapiens (human)
ARPC1B hsa:10095 path:hsa05135 Yersinia infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP ARPC1B 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 ARPC1B 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ARPC1B 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 ARPC1B 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 ARPC1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ARPC1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ARPC1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ARPC1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ARPC1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ARPC1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ARPC1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ARPC1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ARPC1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR ARPC1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 ARPC1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040EC3B ARPC1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000015F70F ARPC1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005606AA ARPC1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002F5FEE ARPC1B 23313552 23824327 25416803 26701625 27418678 mrna cleavage,inhibition clip TarBase
URS00000BD6DC ARPC1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000009EA8F ARPC1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000419B5A ARPC1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001270D3 ARPC1B 23824327 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000CBE63 ARPC1B 23824327 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003E5ECC ARPC1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001D6605 ARPC1B 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
AURKA ARPC1B 22135298 phosphorylation N/A PhosphoSite
PAK1 ARPC1B 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
ARPC3 ARPC1B 20404198 24234451 25348397 26655834 association,physical association anti tag coimmunoprecipitation,fluorescent resonance energy transfer,molecular sieving,pull down,physical interaction,ion exchange chromatography ComPPI,IntAct
WASL ARPC1B 11943145 15894313 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
ANP32B ARPC1B 25348397 N/A physical interaction ComPPI
TPD52L2 ARPC1B 25348397 N/A physical interaction ComPPI
WAS ARPC1B 10861055 11943145 14525934 24234451 25348397 colocalization,physical association experimental interaction detection,pull down,fluorescence microscopy,in vitro ComPPI,HPRD,IntAct
ACTB ARPC1B 11533442 11721045 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
DR1 ARPC1B 25348397 N/A physical interaction ComPPI
KEAP1 ARPC1B 25348397 N/A physical interaction ComPPI
CRK ARPC1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VBP1 ARPC1B 25348397 N/A physical interaction ComPPI
PRKACB ARPC1B 25348397 N/A physical interaction ComPPI
PAK1 ARPC1B 25348397 N/A physical interaction,in vitro,in vivo ComPPI
SUMO1 ARPC1B 25348397 N/A physical interaction ComPPI
FLNA ARPC1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
U2AF2 ARPC1B 25348397 N/A physical interaction ComPPI
TUBG1 ARPC1B 25348397 N/A physical interaction ComPPI
TOM1L1 ARPC1B 25348397 N/A physical interaction ComPPI
NTRK1 ARPC1B 25348397 N/A physical interaction ComPPI
CALR ARPC1B 25348397 N/A physical interaction ComPPI
ANP32A ARPC1B 25348397 N/A physical interaction ComPPI
CFTR ARPC1B 25348397 N/A physical interaction ComPPI
MYO18A ARPC1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XPO1 ARPC1B 25348397 N/A physical interaction ComPPI
RPA2 ARPC1B 25348397 N/A physical interaction ComPPI
IPO11 ARPC1B 25348397 N/A physical interaction ComPPI
PDCD4 ARPC1B 25348397 N/A physical interaction ComPPI
RANGAP1 ARPC1B 25348397 N/A physical interaction ComPPI
CDK2 ARPC1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AURKA ARPC1B 25348397 N/A physical interaction ComPPI
ACTR3 ARPC1B 20404198 24234451 25348397 26655834 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,molecular sieving,pull down,physical interaction,ion exchange chromatography ComPPI,IntAct
ARPC1B ARPC4 11721045 11741539 14525934 20404198 24234451 25348397 26655834 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,molecular sieving,pull down,physical interaction,ion exchange chromatography,in vitro ComPPI,HPRD,IntAct
ARPC1B ARPC5 11721045 11741539 14525934 20404198 24234451 25348397 26655834 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,molecular sieving,pull down,physical interaction,ion exchange chromatography,in vitro ComPPI,HPRD,IntAct
ARPC1B ACTR2 11721045 11741539 14525934 20404198 24234451 25348397 26496610 26655834 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,molecular sieving,pull down,physical interaction,ion exchange chromatography,in vitro,in vivo ComPPI,HPRD,IntAct
ARPC1B ARPC2 11721045 11741539 14525934 20404198 24234451 25348397 26655834 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,molecular sieving,pull down,physical interaction,ion exchange chromatography,in vitro,in vivo ComPPI,HPRD,IntAct
ARPC1B ACTR3B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ARPC1B LRRK2 25348397 N/A physical interaction ComPPI
ARPC1B APP 25348397 N/A physical interaction ComPPI
ARPC1B ARPC5L 24234451 25348397 26655834 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,molecular sieving,pull down,physical interaction,ion exchange chromatography ComPPI,IntAct
ARPC1B PAN2 25348397 N/A physical interaction ComPPI
ARPC1B SRPK2 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
ARPC1B AARS1 25348397 N/A physical interaction ComPPI
ARPC1B BTF3L4 25348397 N/A physical interaction ComPPI
ARPC1B DHPS 25348397 N/A physical interaction ComPPI
ARPC1B METTL1 25348397 N/A physical interaction ComPPI
ARPC1B TPD52 25348397 N/A physical interaction ComPPI
ARPC1B GON7 25348397 N/A physical interaction ComPPI
ARPC1B HSF1 25348397 N/A physical interaction ComPPI
ARPC1B TPRKB 25348397 N/A physical interaction ComPPI
ARPC1B UBE3A 25348397 N/A physical interaction ComPPI
ARPC1B MOV10 25348397 N/A physical interaction ComPPI
ARPC1B POGK 25348397 N/A physical interaction ComPPI
ARPC1B NT5C 25348397 N/A physical interaction ComPPI
ARPC1B CAPZA2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARPC1B DBN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARPC1B MYH9 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARPC1B MYO1C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARPC1B SYNPO 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARPC1B LIMA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARPC1B MYO5C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARPC1B MYO19 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARPC1B TRIM25 25348397 N/A physical interaction ComPPI
ARPC1B G3BP1 25348397 N/A physical interaction ComPPI
ARPC1B PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
PPP2R5D ARPC1B 25348397 N/A physical interaction ComPPI
CALU ARPC1B 25348397 N/A physical interaction ComPPI
ARPC1B UBTD1 24234451 30021884 physical association cross-linking study IntAct
ARPC1B ME1 24234451 30021884 physical association cross-linking study IntAct
ARPC1B ASH1L 24234451 30021884 physical association cross-linking study IntAct
ARPC1B FAM227A 24234451 30021884 physical association cross-linking study IntAct
L1TD1 ARPC1B 24234451 25702638 association anti bait coimmunoprecipitation IntAct
CDH1 ARPC1B 11882288 27898060 stimulant N/A OmniPath
PAK1 ARPC1B 14749719 26160174 27898060 stimulant N/A OmniPath
WASF1 ARPC1B 10781580 27898060 stimulant N/A OmniPath

Visualization










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