Gene Information gene info

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GENE：BRAP

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol BRAP
FullNmae BRCA1 associated protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1099
EnsembleID ENSG00000089234
Uniprot Q7Z569

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
BRAP autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
BRAP GO:0000151,GO:0000165,GO:0000165,GO:0003676,GO:0004842,GO:0005515,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0007265,GO:0007265,GO:0008139,GO:0008270,GO:0009968,GO:0016567,GO:0016567,GO:0016567,GO:0031965,GO:0042802,GO:0061630,GO:0061630,GO:0061630

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
BRAP hsa:8315 path:hsa04014 Ras signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
KSR1 BRAP 14724641 18332145 23180781 physical association anti tag coimmunoprecipitation InnateDB
BRAP MAP2K1 18332145 23180781 physical association anti tag coimmunoprecipitation InnateDB
BRAP KSR1 18332145 23180781 physical association anti tag coimmunoprecipitation InnateDB
LGALS2 BRAP 19198608 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
GATA3 BRAP 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 BRAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF BRAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 BRAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 BRAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 BRAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS BRAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A BRAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000170CF4 BRAP 20018759 rna interference,inhibition array technology,experimental interaction detection miRSponge
URS0000170CF4 BRAP 20018759 25416803 mrna cleavage,inhibition array technology,experimental interaction detection TarBase
URS000002103A BRAP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000042B108 BRAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001B0D1E BRAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B BRAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000BB229 BRAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB BRAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000F6E49 BRAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000202460 BRAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 BRAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000052E1A6 BRAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003D4175 BRAP 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
BRAP BRCA1 25361965 interaction type N/A PTMCode2
BRCA1 BRAP 25361965 interaction type N/A PTMCode2
BRAP CENPF 25361965 interaction type N/A PTMCode2
CENPF BRAP 25361965 interaction type N/A PTMCode2
BRAP ARIH1 25361965 interaction type N/A PTMCode2
ARIH1 BRAP 25361965 interaction type N/A PTMCode2
BRAP IMPA1 25361965 interaction type N/A PTMCode2
IMPA1 BRAP 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SMARCE1 BRAP 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
YJU2 BRAP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CDKN1A BRAP 25348397 N/A physical interaction ComPPI
FBXO2 BRAP 25348397 N/A physical interaction ComPPI
HRAS BRAP 14724641 24234451 25348397 physical association coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
TWIST1 BRAP 21983900 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
CPNE1 BRAP 25348397 N/A physical interaction ComPPI
UBB BRAP 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
UBC BRAP 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
APOA1 BRAP 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
SERPINB13 BRAP 25348397 N/A physical interaction ComPPI
IKBKB BRAP 25348397 N/A physical interaction ComPPI
MAP2K1 BRAP 25348397 N/A physical interaction ComPPI
HMG20A BRAP 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
AKAP3 BRAP 24234451 25348397 25820252 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
USP4 BRAP 25348397 N/A physical interaction ComPPI
NFKBIB BRAP 25348397 N/A physical interaction ComPPI
NEDD8 BRAP 25348397 N/A physical interaction ComPPI
CUL2 BRAP 25348397 N/A physical interaction ComPPI
CUL1 BRAP 25348397 N/A physical interaction ComPPI
RAF1 BRAP 25348397 N/A physical interaction ComPPI
CDC14A BRAP 19152073 25348397 27898060 N/A physical interaction ComPPI,OmniPath
BRK1 BRAP 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
DDB1 BRAP 10777491 24234451 25348397 physical association two hybrid ComPPI,IntAct
ZNF521 BRAP 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
EFHC1 BRAP 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
UBE2H BRAP 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BRAF BRAP 25348397 N/A physical interaction ComPPI
BRCA1 BRAP 24234451 25348397 9497340 physical association two hybrid,pull down,physical interaction ComPPI,IntAct
ZNF382 BRAP 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
TRIM55 BRAP 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM8 BRAP 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RBM12 BRAP 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
FBXO28 BRAP 24234451 25348397 25820252 physical association two hybrid ComPPI,IntAct
TRIM41 BRAP 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NUMA1 BRAP 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
DNMT1 BRAP 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
KSR1 BRAP 14724641 24234451 25348397 physical association coimmunoprecipitation,physical interaction ComPPI,IntAct
SYNE2 BRAP 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
SPRTN BRAP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP15 BRAP 25348397 N/A physical interaction ComPPI
KLHDC3 BRAP 25348397 N/A physical interaction ComPPI
BRAP ZNF526 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BRAP CCDC105 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
BRAP SHCBP1L 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
BRAP TEX35 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
BRAP PHLPP1 24234451 25348397 25820252 colocalization,physical association two hybrid,physical interaction,confocal microscopy ComPPI,IntAct
BRAP FAM184A 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
BRAP ZNF479 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
BRAP TANC2 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
BRAP ATMIN 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
BRAP CCDC30 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
BRAP PRODH 25348397 N/A physical interaction ComPPI
BRAP CPLANE1 24234451 25348397 25820252 physical association two hybrid ComPPI,IntAct
BRAP BRAP 14724641 24234451 25820252 physical association two hybrid,coimmunoprecipitation IntAct
LGALS2 BRAP 19198608 27898060 N/A N/A OmniPath
BRAP MAP2K1 18332145 27898060 N/A N/A OmniPath

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