GENE:CCR1
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | CCR1 |
FullNmae | C-C motif chemokine receptor 1 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:1602 |
EnsembleID | ENSG00000163823 |
Uniprot | P32246 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
CCR1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
CCR1 | GO:0002407,GO:0004435,GO:0004950,GO:0005515,GO:0005737,GO:0005886,GO:0005886,GO:0005886,GO:0006816,GO:0006874,GO:0006887,GO:0006935,GO:0006954,GO:0006955,GO:0006955,GO:0007155,GO:0007166,GO:0007187,GO:0007204,GO:0007204,GO:0007267,GO:0009611,GO:0009897,GO:0009897,GO:0010629,GO:0016493,GO:0016493,GO:0019221,GO:0019722,GO:0019957,GO:0030335,GO:0030502,GO:0035717,GO:0035717,GO:0045672,GO:0051928,GO:0060326,GO:0070098,GO:0070374,GO:0071791,GO:0071791,GO:0090026 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
CCR1 | hsa:1230 | path:hsa04060 | Cytokine-cytokine receptor interaction - Homo sapiens (human) |
CCR1 | hsa:1230 | path:hsa04061 | Viral protein interaction with cytokine and cytokine receptor - Homo sapiens (human) |
CCR1 | hsa:1230 | path:hsa04062 | Chemokine signaling pathway - Homo sapiens (human) |
CCR1 | hsa:1230 | path:hsa05163 | Human cytomegalovirus infection - Homo sapiens (human) |
CCR1 | hsa:1230 | path:hsa05167 | Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
CCR1 | CCL7 | 12381680 23180781 7545673 8530354 | physical association | competition binding | InnateDB |
CCR1 | CCL8 | 23180781 9115216 | physical association | competition binding | InnateDB |
CCR1 | CCL2 | 23180781 9115216 | physical association | competition binding | InnateDB |
CCL26 | CCR1 | 15039444 23180781 | physical association | competition binding | InnateDB |
CCL3 | CCR1 | 12381680 23180781 23765404 7545673 8530354 9115216 | physical association | scintillation proximity assay,competition binding | InnateDB |
CCL5 | CCR1 | 23180781 7545673 8530354 9115216 | physical association | competition binding | InnateDB |
CCL23 | CCR1 | 12381680 15905581 23180781 9558365 | physical association | fluorescence technology,competition binding,unspecified method | InnateDB |
CCL4 | CCR1 | 12381680 23180781 | physical association | competition binding | InnateDB |
CCL14 | CCR1 | 12381680 15905581 23180781 9346309 9548457 | physical association | fluorescence technology,competition binding | InnateDB |
CCL16 | CCR1 | 11470772 23180781 | physical association | fluorescence technology | InnateDB |
CCR1 | CCL16 | 11470772 23180781 | physical association | competition binding,unspecified method | InnateDB |
TBX21 | CCR1 | 23180781 23232398 | physical association | anti tag coimmunoprecipitation | InnateDB |
GATA3 | CCR1 | 23180781 23232398 | physical association | anti tag coimmunoprecipitation | InnateDB |
CCR1 | PLP2 | 15474493 23180781 | physical association | anti tag coimmunoprecipitation,two hybrid | InnateDB |
CREB3 | CCR1 | 15001559 23180781 | physical association | anti tag coimmunoprecipitation,two hybrid | InnateDB |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ETS1 | CCR1 | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
YBX1 | CCR1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
FOXP3 | CCR1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
CTCF | CCR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
STAT1 | CCR1 | 16628196 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS000009262D | CCR1 | 21131358 | rna interference,inhibition | miRNA interference luciferase reporter assay | miRSponge |
URS000009262D | CCR1 | 21131358 25416803 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
URS0000236310 | CCR1 | 25416803 28389653 | mrna cleavage,inhibition | quantitative reverse transcription pcr | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
CCL5 | CCR1 | 25361965 | interaction type | N/A | PTMCode2 |
CCR1 | CCL5 | 25361965 | interaction type | N/A | PTMCode2 |
CCL23 | CCR1 | 25361965 | interaction type | N/A | PTMCode2 |
CCR1 | CCL23 | 25361965 | interaction type | N/A | PTMCode2 |
CCL8 | CCR1 | 25361965 | interaction type | N/A | PTMCode2 |
CCR1 | CCL8 | 25361965 | interaction type | N/A | PTMCode2 |
CCL7 | CCR1 | 25361965 | interaction type | N/A | PTMCode2 |
CCR1 | CCL7 | 25361965 | interaction type | N/A | PTMCode2 |
CCR1 | CREB3 | 25361965 | interaction type | N/A | PTMCode2 |
CREB3 | CCR1 | 25361965 | interaction type | N/A | PTMCode2 |
CCL4 | CCR1 | 25361965 | interaction type | N/A | PTMCode2 |
CCR1 | CCL4 | 25361965 | interaction type | N/A | PTMCode2 |
CCL15 | CCR1 | 25361965 | interaction type | N/A | PTMCode2 |
CCR1 | CCL15 | 25361965 | interaction type | N/A | PTMCode2 |
CCL2 | CCR1 | 25361965 | interaction type | N/A | PTMCode2 |
CCR1 | CCL2 | 25361965 | interaction type | N/A | PTMCode2 |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
LENG1 | CCR1 | 25348397 | N/A | physical interaction | ComPPI |
YES1 | CCR1 | 25348397 | N/A | physical interaction | ComPPI |
CDCA3 | CCR1 | 25348397 | N/A | physical interaction | ComPPI |
GNG10 | CCR1 | 25348397 | N/A | physical interaction | ComPPI |
GNA14 | CCR1 | 14525934 25348397 27898060 8626727 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD,OmniPath |
ATP5F1B | CCR1 | 25348397 | N/A | physical interaction | ComPPI |
STAT1 | CCR1 | 14525934 14674010 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
LAMTOR4 | CCR1 | 25348397 | N/A | physical interaction | ComPPI |
PAG1 | CCR1 | 25348397 | N/A | physical interaction | ComPPI |
GNAQ | CCR1 | 25348397 | N/A | physical interaction | ComPPI |
JAK1 | CCR1 | 14525934 14674010 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
CCL5 | CCR1 | 11116158 12270118 14525934 14637022 24234451 25348397 28381538 7545673 9289016 | association,physical association | experimental interaction detection,fluorescence-activated cell sorting,physical interaction,biochemical,in vitro,in vivo | ComPPI,HPRD,IntAct |
EPHA2 | CCR1 | 25348397 | N/A | physical interaction | ComPPI |
GNA13 | CCR1 | 25348397 | N/A | physical interaction | ComPPI |
CCL3 | CCR1 | 10202040 10660125 14525934 25348397 7545673 | N/A | experimental interaction detection,physical interaction,biochemical,in vitro,in vivo | ComPPI,HPRD |
CCL1 | CCR1 | 25348397 | N/A | physical interaction,biochemical | ComPPI |
STXBP2 | CCR1 | 25348397 | N/A | physical interaction | ComPPI |
CCL4 | CCR1 | 14525934 25348397 7594543 | N/A | experimental interaction detection,physical interaction,biochemical,in vitro | ComPPI,HPRD |
CCR1 | CCL14 | 11085751 14525934 25348397 | N/A | experimental interaction detection,physical interaction,biochemical,in vitro,in vivo | ComPPI,HPRD |
CCR1 | CCL15 | 25348397 | N/A | physical interaction,biochemical,in vivo | ComPPI |
CCR1 | CCL16 | 10910894 11470772 14525934 25348397 | N/A | experimental interaction detection,physical interaction,biochemical,in vivo | ComPPI,HPRD |
CCR1 | CCL3L1 | 11449371 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
CCR1 | CCL8 | 14525934 25348397 9115216 | N/A | experimental interaction detection,physical interaction,biochemical,in vivo | ComPPI,HPRD |
CCR1 | CCL23 | 25348397 | N/A | physical interaction,in vivo | ComPPI |
CCR1 | PLP2 | 14525934 15474493 24234451 25348397 | colocalization,physical association | anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,imaging technique,in vivo,two hybrid | ComPPI,HPRD,IntAct |
CCR1 | CREB3 | 25348397 | N/A | two hybrid,two hybrid,in vivo | ComPPI |
CCR1 | STAT3 | 14525934 14674010 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
CCR1 | CCL26 | 14525934 15039444 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
CCR1 | TPST1 | 14525934 17558413 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
CCR1 | TPST2 | 14525934 17558413 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
CCR1 | CCL2 | 14525934 25348397 8631787 | N/A | experimental interaction detection,physical interaction,biochemical,in vitro | ComPPI,HPRD |
CCR1 | GAP43 | 25348397 | N/A | physical interaction | ComPPI |
CCR1 | SETD7 | 25348397 | N/A | physical interaction | ComPPI |
CCR1 | OCC1 | 25348397 | N/A | physical interaction | ComPPI |
CCR1 | TMX1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
CCL7 | CCR1 | 25348397 | N/A | experimental interaction detection,physical interaction,physical interaction,biochemical,in vitro,in vivo | ComPPI |
CCR1 | CCR1 | 10202040 14525934 | N/A | experimental interaction detection | HPRD |
MBP | CCR1 | 24234451 28298427 | physical association | bioluminescence resonance energy transfer,ubiquitin reconstruction | IntAct |
CCR1 | PRNP | 24234451 28298427 | physical association | bioluminescence resonance energy transfer,ubiquitin reconstruction | IntAct |
CCR1 | CD74 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |
CCR1 | GRAMD1A | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |
CCR1 | LETMD1 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |
CCR1 | FAN1 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |
CCR1 | QSOX1 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |
TMEFF1 | CCR1 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |
HNRNPU | CCR1 | 24234451 30021884 | physical association | cross-linking study | IntAct |
CCR1 | CCR2 | 17924945 18987006 27898060 | N/A | N/A | OmniPath |
CCR1 | CCL8 | 27898060 9115216 | N/A | N/A | OmniPath |
CCL8 | CCR1 | 24218476 27898060 9115216 | stimulant | N/A | OmniPath |
CCL5 | CCR1 | 10734056 10910894 11116158 11449371 12270118 14637022 24218476 27898060 7545673 7622448 8530354 9115216 9289016 9336350 9624164 | stimulant | N/A | OmniPath |
CCL3L1 | CCR1 | 11449371 24218476 27898060 | stimulant | N/A | OmniPath |
CCL4 | CCR1 | 10910894 12381680 27898060 7545673 7594543 8530354 | stimulant | N/A | OmniPath |
CCL2 | CCR1 | 27898060 7679328 8631787 9115216 | stimulant | N/A | OmniPath |
CREB3 | CCR1 | 15001559 27898060 | N/A | N/A | OmniPath |
CCL3 | CCR1 | 10202040 10488147 10498628 10660125 10734056 10910894 11170631 12381680 20219869 23765404 24218476 27898060 7545673 7622448 8530354 9115216 9169459 9207005 9336350 9624164 9687537 | stimulant | N/A | OmniPath |
CCR1 | PLP2 | 15474493 27898060 | N/A | N/A | OmniPath |
CCL26 | CCR1 | 15039444 24218476 27898060 | stimulant | N/A | OmniPath |
CCL14 | CCR1 | 11085751 12381680 15905581 24218476 27898060 9346309 9548457 9687537 | stimulant | N/A | OmniPath |
CCL16 | CCR1 | 10910894 11470772 24218476 27898060 | stimulant | N/A | OmniPath |
CCL15 | CCR1 | 27898060 9346309 | stimulant | N/A | OmniPath |
CCL23 | CCR1 | 10660125 12381680 24218476 27898060 9558365 9886417 | stimulant | N/A | OmniPath |
CCL7 | CCR1 | 11994538 12381680 14991608 24218476 27898060 7545673 8530354 9336350 | stimulant | N/A | OmniPath |