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GENE：CDKN3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CDKN3
FullNmae cyclin dependent kinase inhibitor 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1791
EnsembleID ENSG00000100526
Uniprot Q16667

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CDKN3 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CDKN3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CDKN3 cuproptosis 36313717 The details of ninety-six candidate cuproptosis-related genes involved in the copper homeostasis regulatory pathway, copper metabolism diseases, mitochondrial respiratory, and iron-sulfur cluster proteins were exhibited in聽Table S1. Cuproptosis genes related mitochondrial respiration

Go Annotation:

GeneSymbol Go id
CDKN3 GO:0000079,GO:0000082,GO:0004722,GO:0004725,GO:0004725,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0008138,GO:0008285,GO:0016311,GO:0017018,GO:0048471,GO:0051726

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CDKN3 EGR1 19374776 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 CDKN3 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 CDKN3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 CDKN3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 CDKN3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CDKN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CDKN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CDKN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CDKN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CDKN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CDKN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CDKN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CDKN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 CDKN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 CDKN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
YBX1 CDKN3 20596676 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001EFBE3 CDKN3 19944095 rna interference,inhibition western blot miRSponge
URS00001EFBE3 CDKN3 19944095 25416803 mrna cleavage,inhibition western blot TarBase
URS00000F31F4 CDKN3 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 CDKN3 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00001FC26E CDKN3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 CDKN3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000005CE28 CDKN3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEF5F CDKN3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD CDKN3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001597DC CDKN3 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
BMI1 CDKN3 25348397 N/A physical interaction ComPPI
ROCK1 CDKN3 25348397 N/A physical interaction ComPPI
NCOA3 CDKN3 25348397 N/A physical interaction ComPPI
PPP1R12A CDKN3 25348397 N/A physical interaction ComPPI
BAG6 CDKN3 25348397 N/A physical interaction ComPPI
HAX1 CDKN3 25348397 N/A physical interaction ComPPI
CLPB CDKN3 25348397 N/A physical interaction ComPPI
RAD23A CDKN3 25348397 N/A physical interaction ComPPI
CDK2 CDKN3 11463386 12745075 14525934 15530371 24218572 24234451 25348397 25852190 7569954 8242750 8242751 9840943 dephosphorylation reaction,association,physical association anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,x-ray crystallography,physical interaction,genetic,phosphatase assay,in vitro,in vivo,lexa b52 complementation,two hybrid ComPPI,HPRD,IntAct
DLAT CDKN3 25348397 N/A physical interaction ComPPI
RAD23B CDKN3 25348397 N/A physical interaction ComPPI
GOPC CDKN3 25348397 N/A physical interaction ComPPI
ROCK2 CDKN3 25348397 N/A physical interaction ComPPI
NAP1L4 CDKN3 25348397 N/A physical interaction ComPPI
SEC63 CDKN3 25348397 N/A physical interaction ComPPI
CEBPA CDKN3 11684017 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CDC25A CDKN3 14525934 25348397 27898060 9989807 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
CDKN3 CDK3 14525934 24218572 24234451 25348397 8242750 physical association two hybrid,experimental interaction detection,genetic,in vivo,lexa b52 complementation,two hybrid ComPPI,HPRD,IntAct
CDKN3 MS4A3 11781350 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,OmniPath
CDKN3 CDK1 14525934 24218572 24234451 25348397 8127873 8242750 physical association two hybrid,experimental interaction detection,physical interaction,genetic,lexa b52 complementation,two hybrid ComPPI,HPRD,IntAct
CDKN3 CDC42BPB 25348397 N/A physical interaction ComPPI
CDKN3 ARHGEF28 25348397 N/A physical interaction ComPPI
CDKN3 HDHD5 25348397 N/A physical interaction ComPPI
CDKN3 DIS3L 25348397 N/A physical interaction ComPPI
CDKN3 CDKN3 14525934 8127873 8242750 N/A two hybrid HPRD
CDKN3 CDK2 11463386 12745075 15530371 24218572 25852190 26186194 27898060 7569954 8127873 8242750 8242751 9840943 inhibition N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009BA40C CDKN3 27087310 direct interaction,inhibition N/A NPInter

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