GENE:CPE
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CPE |
| FullNmae | carboxypeptidase E |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:2303 |
| EnsembleID | ENSG00000109472 |
| Uniprot | P16870 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CPE | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| CPE | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CPE | GO:0003214,GO:0004180,GO:0004181,GO:0005515,GO:0005615,GO:0005794,GO:0005886,GO:0006518,GO:0007218,GO:0008270,GO:0016055,GO:0016485,GO:0030070,GO:0030072,GO:0030658,GO:0030667,GO:0033366,GO:0036211,GO:0042043,GO:0050839,GO:0070062,GO:0072657 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| CPE | hsa:1363 | path:hsa04940 | Type I diabetes mellitus - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ESR1 | CPE | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA1 | CPE | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | CPE | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXA1 | CPE | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | CPE | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PRDM14 | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | CPE | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00002075FA | CPE | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001EE123 | CPE | 24374217 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006372A | CPE | 24374217 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000192A75 | CPE | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000235862 | CPE | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000383DF4 | CPE | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001310DE | CPE | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000081D1E | CPE | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000519450 | CPE | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000475586 | CPE | 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000016FF9C | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001D4A78 | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CC379 | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075B538 | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FC26E | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000160683 | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C5969 | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000085F64 | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E2232 | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000031B6ED | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039E1E1 | CPE | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C0099 | CPE | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000355E82 | CPE | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003FBC84 | CPE | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041FA2C | CPE | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F2EB0 | CPE | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000010F787 | CPE | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS000006F90B | CPE | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS00002CEB74 | CPE | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS0000021D08 | CPE | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS0000195F5B | CPE | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SLAMF1 | CPE | 25348397 | N/A | physical interaction | ComPPI |
| INS | CPE | 10966857 14525934 25348397 7477119 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| PMCH | CPE | 14525934 25348397 8770919 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| PRKAA1 | CPE | 20368287 24234451 25348397 | physical association | pull down,physical interaction | ComPPI,IntAct |
| RPA1 | CPE | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| POLDIP2 | CPE | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| TRH | CPE | 12270926 14525934 25348397 27898060 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD,OmniPath |
| UTP14A | CPE | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| NUFIP1 | CPE | 25348397 | N/A | physical interaction | ComPPI |
| LRIF1 | CPE | 14525934 16169070 25348397 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD |
| RIF1 | CPE | 16169070 24234451 25348397 | physical association | two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
| BDNF | CPE | 14525934 15664176 25348397 27898060 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD,OmniPath |
| ROBO2 | CPE | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| MED31 | CPE | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| SCGB1D1 | CPE | 25348397 | N/A | physical interaction | ComPPI |
| CPE | GAST | 14525934 25348397 9369230 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| CPE | GCG | 11375130 14525934 25348397 27898060 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD,OmniPath |
| CPE | GTF3C1 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| CPE | POLA2 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| CPE | CHD3 | 14525934 16169070 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| CPE | SIAE | 25348397 | N/A | physical interaction | ComPPI |
| CPE | RNASE13 | 25348397 | N/A | physical interaction | ComPPI |
| CPE | PSG8 | 25348397 | N/A | physical interaction | ComPPI |
| CPE | PSG1 | 25348397 | N/A | physical interaction | ComPPI |
| CPE | CCK | 12479974 14525934 9275097 | N/A | experimental interaction detection | HPRD |
| NTS | CPE | 14525934 8770919 | N/A | experimental interaction detection | HPRD |
| CPE | INS | 10966857 27898060 7477119 | N/A | N/A | OmniPath |
| CPE | CCK | 12479974 27898060 9275097 | N/A | N/A | OmniPath |
| CPE | GAST | 27898060 9369230 | N/A | N/A | OmniPath |
