GENE:CPE
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | CPE |
FullNmae | carboxypeptidase E |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:2303 |
EnsembleID | ENSG00000109472 |
Uniprot | P16870 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
CPE | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
CPE | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
CPE | GO:0003214,GO:0004180,GO:0004181,GO:0005515,GO:0005615,GO:0005794,GO:0005886,GO:0006518,GO:0007218,GO:0008270,GO:0016055,GO:0016485,GO:0030070,GO:0030072,GO:0030658,GO:0030667,GO:0033366,GO:0036211,GO:0042043,GO:0050839,GO:0070062,GO:0072657 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
CPE | hsa:1363 | path:hsa04940 | Type I diabetes mellitus - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ESR1 | CPE | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA1 | CPE | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA2 | CPE | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
FOXA1 | CPE | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
FOXP3 | CPE | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
SMARCA4 | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXP1 | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
PRDM14 | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TAL1 | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TP53 | CPE | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000237AF9 | CPE | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00002075FA | CPE | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00001EE123 | CPE | 24374217 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000006372A | CPE | 24374217 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000192A75 | CPE | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000235862 | CPE | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000383DF4 | CPE | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001310DE | CPE | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000081D1E | CPE | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000519450 | CPE | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000475586 | CPE | 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
URS000016FF9C | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001D4A78 | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001CC379 | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075B538 | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001FC26E | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000160683 | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000C5969 | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000085F64 | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000076B539 | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003E2232 | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000031B6ED | CPE | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000039E1E1 | CPE | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001C0099 | CPE | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000355E82 | CPE | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003FBC84 | CPE | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000041FA2C | CPE | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004F2EB0 | CPE | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000010F787 | CPE | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
URS000006F90B | CPE | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
URS00002CEB74 | CPE | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
URS0000021D08 | CPE | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
URS0000195F5B | CPE | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
SLAMF1 | CPE | 25348397 | N/A | physical interaction | ComPPI |
INS | CPE | 10966857 14525934 25348397 7477119 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
PMCH | CPE | 14525934 25348397 8770919 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
PRKAA1 | CPE | 20368287 24234451 25348397 | physical association | pull down,physical interaction | ComPPI,IntAct |
RPA1 | CPE | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
POLDIP2 | CPE | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
TRH | CPE | 12270926 14525934 25348397 27898060 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD,OmniPath |
UTP14A | CPE | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
NUFIP1 | CPE | 25348397 | N/A | physical interaction | ComPPI |
LRIF1 | CPE | 14525934 16169070 25348397 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD |
RIF1 | CPE | 16169070 24234451 25348397 | physical association | two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
BDNF | CPE | 14525934 15664176 25348397 27898060 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD,OmniPath |
ROBO2 | CPE | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
MED31 | CPE | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
SCGB1D1 | CPE | 25348397 | N/A | physical interaction | ComPPI |
CPE | GAST | 14525934 25348397 9369230 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
CPE | GCG | 11375130 14525934 25348397 27898060 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD,OmniPath |
CPE | GTF3C1 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
CPE | POLA2 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
CPE | CHD3 | 14525934 16169070 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
CPE | SIAE | 25348397 | N/A | physical interaction | ComPPI |
CPE | RNASE13 | 25348397 | N/A | physical interaction | ComPPI |
CPE | PSG8 | 25348397 | N/A | physical interaction | ComPPI |
CPE | PSG1 | 25348397 | N/A | physical interaction | ComPPI |
CPE | CCK | 12479974 14525934 9275097 | N/A | experimental interaction detection | HPRD |
NTS | CPE | 14525934 8770919 | N/A | experimental interaction detection | HPRD |
CPE | INS | 10966857 27898060 7477119 | N/A | N/A | OmniPath |
CPE | CCK | 12479974 27898060 9275097 | N/A | N/A | OmniPath |
CPE | GAST | 27898060 9369230 | N/A | N/A | OmniPath |