Gene Information gene info

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GENE：CUX1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CUX1
FullNmae cut like homeobox 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2557
EnsembleID ENSG00000257923
Uniprot P39880|Q13948

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CUX1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CUX1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CUX1 GO:0000122,GO:0000785,GO:0000977,GO:0000977,GO:0000981,GO:0000981,GO:0005634,GO:0005634,GO:0005654,GO:0005794,GO:0005829,GO:0006357,GO:0043565,GO:0050775,GO:1990837

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR CUX1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
AR CUX1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 CUX1 17531812 18347061 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
E2F4 CUX1 17531812 18347061 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 CUX1 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 CUX1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 CUX1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 CUX1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 CUX1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 CUX1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C CUX1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C CUX1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CUX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CUX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CUX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CUX1 18347061 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CUX1 18347061 trascriptional regulation,stimulation inferred by curator TFlink
E2F2 CUX1 18347061 trascriptional regulation,stimulation inferred by curator TFlink
E2F2 CUX1 18347061 trascriptional regulation,stimulation inferred by curator TFlink
E2F3 CUX1 18347061 trascriptional regulation,stimulation inferred by curator TFlink
E2F3 CUX1 18347061 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 CUX1 18668040 19193853 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,quantitative reverse transcription pcr TarBase
URS0000070B1D CUX1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AD002 CUX1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000A057E CUX1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 CUX1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PRKACA CUX1 22135298 phosphorylation N/A PhosphoSite
ATR CUX1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
CTSL CUX1 25348397 N/A in vitro,in vivo ComPPI
TP53BP1 CUX1 25348397 N/A physical interaction ComPPI
TP53BP1 CUX1 25348397 N/A physical interaction ComPPI
WDR83 CUX1 25348397 N/A physical interaction ComPPI
WDR83 CUX1 25348397 N/A physical interaction ComPPI
EHMT2 CUX1 25348397 N/A physical interaction,in vitro ComPPI
EHMT2 CUX1 14525934 15269344 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
TACC3 CUX1 25348397 N/A physical interaction ComPPI
TACC3 CUX1 25348397 N/A physical interaction ComPPI
FOXG1 CUX1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXG1 CUX1 25348397 N/A physical interaction ComPPI
NFATC1 CUX1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NFATC1 CUX1 25348397 N/A physical interaction ComPPI
JUN CUX1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
JUN CUX1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
RB1 CUX1 25348397 N/A two hybrid,physical interaction,in vivo ComPPI
RB1 CUX1 12891711 14525934 24234451 25348397 27898060 colocalization,physical association two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,imaging technique,two hybrid ComPPI,HPRD,IntAct,OmniPath
CREBBP CUX1 25348397 N/A physical interaction,in vitro,in vivo ComPPI
CREBBP CUX1 10852958 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
KAT2B CUX1 25348397 N/A physical interaction,in vitro ComPPI
KAT2B CUX1 10852958 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PTH1R CUX1 25348397 N/A physical interaction ComPPI
PTH1R CUX1 25348397 N/A physical interaction ComPPI
NTRK1 CUX1 25348397 N/A physical interaction ComPPI
NTRK1 CUX1 25348397 N/A physical interaction ComPPI
NIT1 CUX1 25348397 N/A physical interaction ComPPI
HNRNPL CUX1 25348397 N/A physical interaction ComPPI
HNRNPL CUX1 25348397 N/A physical interaction ComPPI
CYTH2 CUX1 25348397 N/A two hybrid,in vitro,in vivo ComPPI
HMGB1 CUX1 25348397 N/A in vitro ComPPI
ECT2 CUX1 25348397 N/A physical interaction ComPPI
ECT2 CUX1 25348397 N/A physical interaction ComPPI
CCNA1 CUX1 25348397 N/A physical interaction ComPPI
CCNA1 CUX1 25348397 N/A physical interaction ComPPI
SUMO2 CUX1 25348397 N/A physical interaction ComPPI
SUMO2 CUX1 25348397 N/A physical interaction ComPPI
BIN1 CUX1 25348397 N/A two hybrid,physical interaction ComPPI
BIN1 CUX1 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SOX2 CUX1 25348397 N/A physical interaction ComPPI
SOX2 CUX1 25348397 N/A physical interaction ComPPI
SDC3 CUX1 25348397 N/A in vitro ComPPI
CDK7 CUX1 25348397 N/A physical interaction ComPPI
CDK7 CUX1 25348397 N/A physical interaction ComPPI
H3C1 CUX1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
FOXE1 CUX1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TRIM25 CUX1 25348397 N/A physical interaction ComPPI
TRIM25 CUX1 25348397 N/A physical interaction ComPPI
SATB1 CUX1 25348397 N/A physical interaction,in vitro,in vivo ComPPI
SATB1 CUX1 10373541 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
RECQL5 CUX1 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ELAC2 CUX1 25348397 N/A two hybrid,physical interaction ComPPI
ELAC2 CUX1 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ILKAP CUX1 24234451 25348397 28330616 association pull down ComPPI,IntAct
STX6 CUX1 25348397 N/A physical interaction ComPPI
STX6 CUX1 25348397 N/A physical interaction ComPPI
FOXP1 CUX1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXP1 CUX1 25348397 N/A physical interaction ComPPI
BET1 CUX1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MAX CUX1 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
MAX CUX1 25348397 N/A physical interaction ComPPI
CUX1 CDC25A 25348397 N/A in vitro,in vivo ComPPI
CUX1 CDK1 25348397 N/A physical interaction ComPPI
CUX1 TLE4 25348397 N/A physical interaction ComPPI
CUX1 KCND3 25348397 N/A physical interaction ComPPI
CUX1 HLA-DQA1 25348397 N/A physical interaction ComPPI
CUX1 RBPJ 25348397 N/A physical interaction ComPPI
CUX1 GAN 25348397 N/A physical interaction ComPPI
CUX1 FOXK2 25348397 N/A physical interaction ComPPI
CUX1 FOXO1 25348397 N/A physical interaction ComPPI
CUX1 FOXQ1 25348397 N/A physical interaction ComPPI
CUX1 EXT2 25348397 N/A physical interaction ComPPI
CUX1 RAB30 25348397 N/A physical interaction ComPPI
CUX1 CNBP 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
KCND3 CUX1 25348397 N/A physical interaction ComPPI
FOXO1 CUX1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
RBPJ CUX1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
RAB30 CUX1 25348397 N/A physical interaction ComPPI
HLA-DQA1 CUX1 25348397 N/A physical interaction ComPPI
CA12 CUX1 14525934 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
EXT2 CUX1 25348397 N/A physical interaction ComPPI
FOXK2 CUX1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
LAMP1 CUX1 25348397 N/A physical interaction ComPPI
FOXD3 CUX1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
CUX1 CDK1 11584018 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
CUX1 TLE4 19332113 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CUX1 MAGEA10 25348397 N/A physical interaction ComPPI
CUX1 GABRE 25348397 N/A physical interaction ComPPI
CUX1 SLC39A4 25348397 N/A physical interaction ComPPI
CUX1 SPATS2L 25348397 N/A physical interaction ComPPI
CUX1 FOXJ2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
CUX1 GAN 25348397 N/A physical interaction ComPPI
CUX1 FOXN1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
CUX1 FOXQ1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
CUX1 SLC39A12 25348397 N/A physical interaction ComPPI
CUX1 POTEB3 25348397 N/A physical interaction ComPPI
CTSL CUX1 14525934 15099520 N/A experimental interaction detection HPRD
CDC25A CUX1 11584018 14525934 N/A experimental interaction detection HPRD
HMGB1 CUX1 11748221 14525934 N/A experimental interaction detection HPRD
SDC3 CUX1 14525934 27898060 8662884 N/A experimental interaction detection HPRD,OmniPath
CYTH2 CUX1 12052827 14525934 27898060 N/A experimental interaction detection,two hybrid HPRD,OmniPath
NCBP2 CUX1 24234451 26382858 association pull down IntAct
KRT8 CUX1 24234451 30021884 physical association cross-linking study IntAct
CUX1 GOLGA5 15718469 27898060 N/A N/A OmniPath
PRKACA CUX1 16574653 27898060 N/A N/A OmniPath
CDC25A CUX1 11584018 27898060 9707427 N/A N/A OmniPath
CTSL CUX1 15099520 27898060 N/A N/A OmniPath
CDK1 CUX1 11584018 16574653 27898060 inhibition N/A OmniPath

Visualization










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