Gene Information gene info

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GENE：CXCL3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CXCL3
FullNmae C-X-C motif chemokine ligand 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4604
EnsembleID ENSG00000163734
Uniprot P19876

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CXCL3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CXCL3 GO:0005576,GO:0005615,GO:0005615,GO:0006954,GO:0008009,GO:0008009,GO:0030593,GO:0030593,GO:0045236,GO:0061844,GO:0070098,GO:0071222

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CXCL3 hsa:2921 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
CXCL3 hsa:2921 path:hsa04061 Viral protein interaction with cytokine and cytokine receptor - Homo sapiens (human)
CXCL3 hsa:2921 path:hsa04062 Chemokine signaling pathway - Homo sapiens (human)
CXCL3 hsa:2921 path:hsa04064 NF-kappa B signaling pathway - Homo sapiens (human)
CXCL3 hsa:2921 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)
CXCL3 hsa:2921 path:hsa04657 IL-17 signaling pathway - Homo sapiens (human)
CXCL3 hsa:2921 path:hsa04668 TNF signaling pathway - Homo sapiens (human)
CXCL3 hsa:2921 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)
CXCL3 hsa:2921 path:hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human)
CXCL3 hsa:2921 path:hsa05134 Legionellosis - Homo sapiens (human)
CXCL3 hsa:2921 path:hsa05146 Amoebiasis - Homo sapiens (human)
CXCL3 hsa:2921 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)
CXCL3 hsa:2921 path:hsa05323 Rheumatoid arthritis - Homo sapiens (human)
CXCL3 hsa:2921 path:hsa05417 Lipid and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CXCL3 RELA 15722553 23180781 physical association anti tag coimmunoprecipitation InnateDB
MMP12 CXCL3 18660381 23180781 protein cleavage protease assay InnateDB

Source Target Pmid Interactiontype Methods Database
AR CXCL3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 CXCL3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CXCL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 CXCL3 N/A trascriptional regulation,stimulation inferred by curator TFlink
REL CXCL3 N/A trascriptional regulation,stimulation inferred by curator TFlink
RELA CXCL3 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000029D9F1 CXCL3 21282569 25416803 mrna cleavage,inhibition array technology TarBase
URS0000237AF9 CXCL3 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000D5659 CXCL3 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001A405B CXCL3 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CXCR2 CXCL3 14525934 25348397 8702798 N/A experimental interaction detection,physical interaction,biochemical,in vivo ComPPI,HPRD
CCL11 CXCL3 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
XCL2 CXCL3 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
CXCL5 CXCL3 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
CXCR1 CXCL3 14525934 25348397 8702798 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CXCL6 CXCL3 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
CXCL3 CXCR2 24218476 27898060 8702798 stimulant N/A OmniPath

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