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GENE：DAAM1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DAAM1
FullNmae dishevelled associated activator of morphogenesis 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18142
EnsembleID ENSG00000100592
Uniprot Q9Y4D1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DAAM1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DAAM1 GO:0001725,GO:0001725,GO:0003779,GO:0005515,GO:0005829,GO:0005829,GO:0005886,GO:0016020,GO:0030036,GO:0031267,GO:0031514,GO:0036064,GO:0042802,GO:0060071

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DAAM1 hsa:23002 path:hsa04310 Wnt signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APC2 DAAM1 11226259 11698448 11729192 11739775 11779461 11992112 12194823 12361600 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15618519 15761148 16713974 17127310 17303408 17517963 17660363 17884187 18037882 18256687 18423981 18497258 18590585 18851840 19020754 19366350 19565474 19836308 19853559 20006983 20351293 20535745 21178402 22017973 22949611 23732914 24857661 24919149 26192618 26885855 26885856 27048821 27066895 7479854 7575488 7641885 8655584 9362522 9660866 9822605 interaction type N/A ACSN
CTHRC1 DAAM1 11226259 11698448 11729192 11739775 11779461 11992112 12194823 12361600 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15618519 15761148 16713974 17127310 17303408 17517963 17660363 17884187 18037882 18256687 18423981 18497258 18590585 18851840 19020754 19366350 19565474 19836308 19853559 20006983 20351293 20535745 21178402 22017973 22949611 23732914 24857661 24919149 26192618 26885855 26885856 27048821 27066895 7479854 7575488 7641885 8655584 9362522 9660866 9822605 interaction type N/A ACSN
RACK1 DAAM1 11226259 11698448 11729192 11739775 11779461 11992112 12194823 12361600 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15618519 15761148 16713974 17127310 17303408 17517963 17660363 17884187 18037882 18256687 18423981 18497258 18590585 18851840 19020754 19366350 19565474 19836308 19853559 20006983 20351293 20535745 21178402 22017973 22949611 23732914 24857661 24919149 26192618 26885855 26885856 27048821 27066895 7479854 7575488 7641885 8655584 9362522 9660866 9822605 interaction type N/A ACSN
RHOA DAAM1 11226259 11698448 11729192 11739775 11779461 11992112 12194823 12361600 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15618519 15761148 16713974 17127310 17303408 17517963 17660363 17884187 18037882 18256687 18423981 18497258 18590585 18851840 19020754 19366350 19565474 19836308 19853559 20006983 20535745 21178402 22017973 22949611 23732914 24857661 24919149 26192618 26885855 26885856 27048821 27066895 7479854 7575488 7641885 8655584 9362522 9660866 9822605 interaction type N/A ACSN
ROR2 DAAM1 11226259 11698448 11729192 11739775 11779461 11992112 12194823 12361600 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15618519 15761148 16713974 17127310 17303408 17517963 17660363 17884187 18037882 18256687 18423981 18497258 18590585 18851840 19020754 19366350 19565474 19836308 19853559 20006983 20351293 20535745 21178402 22017973 22949611 23732914 24857661 24919149 26192618 26885855 26885856 27048821 27066895 7479854 7575488 7641885 8655584 9362522 9660866 9822605 interaction type N/A ACSN
RSPO3 DAAM1 11226259 11698448 11729192 11739775 11779461 11992112 12194823 12361600 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15618519 15761148 16713974 17127310 17303408 17517963 17660363 17884187 18037882 18256687 18423981 18497258 18590585 18851840 19020754 19366350 19565474 19836308 19853559 20006983 20351293 20535745 21178402 22017973 22949611 23732914 24857661 24919149 26192618 26885855 26885856 27048821 27066895 7479854 7575488 7641885 8655584 9362522 9660866 9822605 interaction type N/A ACSN
MAP3K7 DAAM1 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
DAAM1 DAAM1 19365405 23151663 26467481 interaction type,bind,up-regulates activity N/A Signor
DVL1 DAAM1 20006983 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR DAAM1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 DAAM1 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 DAAM1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 DAAM1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 DAAM1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 DAAM1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 DAAM1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 DAAM1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 DAAM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DAAM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DAAM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 DAAM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DAAM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DAAM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DAAM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DAAM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF DAAM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 DAAM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 DAAM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 DAAM1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000009262D DAAM1 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS000000B1C9 DAAM1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000298BA3 DAAM1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000393C7 DAAM1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
DVL2 DAAM1 25361965 interaction type N/A PTMCode2
DAAM1 DVL2 25361965 interaction type N/A PTMCode2
DAAM1 ARHGEF19 25361965 interaction type N/A PTMCode2
ARHGEF19 DAAM1 25361965 interaction type N/A PTMCode2
DAAM1 DVL1 25361965 interaction type N/A PTMCode2
DVL1 DAAM1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TUBB DAAM1 25348397 N/A physical interaction ComPPI
AMBP DAAM1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CD9 DAAM1 23289620 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
RHOB DAAM1 18218625 24234451 25348397 N/A pull down ComPPI,IntAct
RHOC DAAM1 18218625 24234451 25348397 N/A pull down,physical interaction ComPPI,IntAct
RHOA DAAM1 11779461 14525934 18218625 24234451 25241761 25348397 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,surface plasmon resonance,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
DAAM1 DVL1 11779461 14525934 22705156 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,fluorescence microscopy,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
DAAM1 DVL2 11779461 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
DAAM1 MAP3K7 25348397 N/A physical interaction ComPPI
DAAM1 B3GALT4 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DAAM1 RHOD 18218625 24234451 25348397 N/A pull down,physical interaction ComPPI,IntAct
DAAM1 GPN3 25348397 N/A physical interaction ComPPI
DAAM1 TMEM185A 25348397 N/A physical interaction ComPPI
DAAM1 PIFO 25348397 N/A physical interaction ComPPI
DAAM1 CDH1 25348397 N/A physical interaction ComPPI
DAAM1 FBXL16 25348397 N/A physical interaction ComPPI
DAAM1 SERHL2 25348397 N/A physical interaction ComPPI
DAAM1 RANBP6 25348397 N/A physical interaction ComPPI
DAAM1 FBXL14 25348397 N/A physical interaction ComPPI
DAAM1 TUBA4A 25348397 N/A physical interaction ComPPI
DAAM1 ARMC6 25348397 N/A physical interaction ComPPI
DAAM1 SLC37A3 25348397 N/A physical interaction ComPPI
DAAM1 HNRNPL 25348397 N/A physical interaction ComPPI
DAAM1 CFTR 25348397 N/A physical interaction ComPPI
DAAM1 ARHGEF19 18256687 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
DAAM1 MME 23289620 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
DAAM1 FNBP1L 16630611 24234451 25348397 physical association anti bait coimmunoprecipitation,pull down ComPPI,IntAct
DAAM1 FNBP1 16630611 24234451 25348397 physical association pull down ComPPI,IntAct
DAAM1 INTU 24234451 25348397 26644512 physical association anti tag coimmunoprecipitation ComPPI,IntAct
DAAM1 NPHP4 24234451 25348397 26644512 physical association anti tag coimmunoprecipitation ComPPI,IntAct
PRPF40A DAAM1 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CBX5 DAAM1 21888893 24234451 25348397 association tandem affinity purification ComPPI,IntAct
GNAZ DAAM1 25348397 N/A physical interaction ComPPI
DAAM1 DAAM1 16630611 18218625 24234451 physical association pull down IntAct
HSP90B1 DAAM1 24234451 30021884 physical association cross-linking study IntAct
MAP3K7 DAAM1 21903422 27898060 N/A N/A OmniPath
DAAM1 RHOA 11779461 18218625 19365405 25241761 27898060 stimulant N/A OmniPath
DAAM1 RAC1 23151663 27898060 stimulant N/A OmniPath
DVL1 DAAM1 11779461 19365405 22705156 27898060 stimulant N/A OmniPath
DVL1P1 DAAM1 23151663 27898060 stimulant N/A OmniPath

Visualization










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