Gene Information gene info

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GENE：DUSP5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DUSP5
FullNmae dual specificity phosphatase 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3071
EnsembleID ENSG00000138166
Uniprot Q16690

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DUSP5 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DUSP5 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DUSP5 GO:0000165,GO:0001706,GO:0004725,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0006470,GO:0008138,GO:0008138,GO:0008330,GO:0016311,GO:0016791,GO:0017017,GO:0017018,GO:0033550,GO:0035335,GO:0035970,GO:0043409,GO:0070371

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DUSP5 hsa:1847 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
DUSP5 hsa:1847 path:hsa04148 Efferocytosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
DUSP5 ELAVL1 19322201 23180781 physical association anti tag coimmunoprecipitation InnateDB
DUSP5 MAPK1 10224087 23331499 stimulation N/A SignaLink
DUSP5 MAPK3 10224087 23331499 7836374 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR DUSP5 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 DUSP5 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 DUSP5 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 DUSP5 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 DUSP5 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 DUSP5 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP53 DUSP5 12944906 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 DUSP5 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 DUSP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DUSP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 DUSP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DUSP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 DUSP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DUSP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DUSP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 DUSP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 DUSP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 DUSP5 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000330617 DUSP5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001B341F DUSP5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004BCD9C DUSP5 20371350 21572407 22012620 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000C85B2 DUSP5 20371350 21572407 22012620 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 DUSP5 20371350 21572407 22012620 22473208 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004DA9DB DUSP5 20371350 21572407 22012620 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000153377 DUSP5 20371350 21572407 22012620 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000B989F DUSP5 20371350 21572407 22012620 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001A7F58 DUSP5 20371350 21572407 22012620 22473208 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000040FA88 DUSP5 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000472A9B DUSP5 20371350 21572407 22012620 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000018C928 DUSP5 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000236310 DUSP5 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 DUSP5 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MAPK3 DUSP5 22135298 phosphorylation N/A PhosphoSite
MAPK1 DUSP5 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
DUSP5 MAPK1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LZTS2 DUSP5 25348397 N/A physical interaction ComPPI
COIL DUSP5 25348397 N/A physical interaction ComPPI
RPS15 DUSP5 25348397 N/A physical interaction ComPPI
MAPK1 DUSP5 14525934 15713638 24234451 25348397 colocalization,physical association two hybrid,experimental interaction detection,pull down,fluorescence microscopy,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
MAPK3 DUSP5 14525934 25348397 7836374 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
DUSP5 ELAVL1 25348397 N/A physical interaction ComPPI
DUSP5 IPO7 25348397 N/A physical interaction ComPPI
DUSP5 TEX10 25348397 N/A physical interaction ComPPI
DUSP5 RPL32 25348397 N/A physical interaction ComPPI
DUSP5 FBXO11 25348397 N/A physical interaction ComPPI
DUSP5 MRPS35 25348397 N/A physical interaction ComPPI
DUSP5 FTSJ3 25348397 N/A physical interaction ComPPI
DUSP5 DENR 25348397 N/A physical interaction ComPPI
DUSP5 RPL5 25348397 N/A physical interaction ComPPI
DUSP5 RPL36 25348397 N/A physical interaction ComPPI
DUSP5 AP3S1 25348397 N/A physical interaction ComPPI
DUSP5 AATK 25348397 N/A physical interaction ComPPI
DUSP5 MAPK3 10224087 12944906 19741200 27898060 7836374 inhibition,stimulant N/A OmniPath
TP53 DUSP5 12944906 27898060 stimulant N/A OmniPath
DUSP5 MAPK14 20626350 27898060 inhibition N/A OmniPath
MAPK1 DUSP5 15713638 19666109 27898060 N/A N/A OmniPath
DUSP5 MAPK1 10224087 15713638 19741200 27898060 inhibition,stimulant N/A OmniPath

Visualization










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