Gene Information gene info

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GENE：FASTK

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FASTK
FullNmae Fas activated serine/threonine kinase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24676
EnsembleID ENSG00000164896
Uniprot Q14296

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FASTK autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FASTK apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FASTK apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
FASTK GO:0000963,GO:0003723,GO:0004674,GO:0005515,GO:0005524,GO:0005759,GO:0006468,GO:0033867,GO:0035770,GO:0043484,GO:0043484,GO:0044528,GO:0097190,GO:0106310

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 FASTK 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CTCF FASTK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 FASTK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FASTK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FASTK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 FASTK 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001597DC FASTK 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002367FA FASTK 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000039E1E1 FASTK 24013584 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000014F13C FASTK 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002004E0 FASTK 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001919B0 FASTK 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA FASTK 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002394F5 FASTK 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000383DF4 FASTK 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002F72ED FASTK 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000272A92 FASTK 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RBPMS FASTK 14525934 16189514 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
HSP90AB1 FASTK 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
CRK FASTK 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
HNRNPH2 FASTK 25348397 N/A physical interaction ComPPI
MDFI FASTK 14525934 16189514 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
HSP90AA1 FASTK 25348397 N/A physical interaction ComPPI
TOP3B FASTK 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
WIPF1 FASTK 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TRIM25 FASTK 25348397 N/A physical interaction ComPPI
TNKS2 FASTK 22153077 24234451 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
CALCOCO2 FASTK 14525934 16189514 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
FASTK TIA1 14525934 25348397 7544399 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
FASTK CHERP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FASTK PRPF31 24234451 25348397 25910212 physical association two hybrid array,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct

Source Target Pmid Interactiontype Methods Database
URS00009C2A29 FASTK 27087310 direct interaction,inhibition N/A NPInter

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