Gene Information gene info

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GENE：GAK

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GAK
FullNmae cyclin G associated kinase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4113
EnsembleID ENSG00000178950
Uniprot O14976

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GAK autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GAK GO:0004674,GO:0005515,GO:0005524,GO:0005737,GO:0005794,GO:0005829,GO:0005925,GO:0006898,GO:0007029,GO:0007030,GO:0007049,GO:0010977,GO:0016020,GO:0016191,GO:0016310,GO:0030276,GO:0030332,GO:0031982,GO:0031982,GO:0034067,GO:0043231,GO:0043231,GO:0048268,GO:0048471,GO:0051085,GO:0051087,GO:0072318,GO:0072318,GO:0072583,GO:0072583,GO:0072659,GO:0090160,GO:0098793,GO:0106310

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP GAK 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 GAK 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA GAK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GAK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 GAK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 GAK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GAK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GAK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GAK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GAK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 GAK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 GAK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC GAK N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EC1BE GAK 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C11BC GAK 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F GAK 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 GAK 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 GAK 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 GAK 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 GAK 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 GAK 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA GAK 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HSPA8 GAK 25361965 interaction type N/A PTMCode2
GAK HSPA8 25361965 interaction type N/A PTMCode2
GAK CCNG1 25361965 interaction type N/A PTMCode2
CCNG1 GAK 25361965 interaction type N/A PTMCode2
GAK AR 25361965 interaction type N/A PTMCode2
AR GAK 25361965 interaction type N/A PTMCode2
CLTC GAK 25361965 interaction type N/A PTMCode2
GAK CLTC 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HSPA8 GAK 10625686 14525934 24234451 24510904 25348397 29568061 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,proximity-dependent biotin identification ComPPI,HPRD,IntAct
PALS1 GAK 25348397 N/A physical interaction ComPPI
GPX7 GAK 25348397 N/A physical interaction ComPPI
HSPBP1 GAK 25348397 N/A physical interaction ComPPI
CALML3 GAK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CALM1 GAK 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
CPSF7 GAK 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
DAB2 GAK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SP1 GAK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CBLC GAK 25348397 N/A physical interaction ComPPI
AR GAK 12864730 14525934 16161052 24234451 25348397 physical association two hybrid,experimental interaction detection,in vitro,in vivo,reverse two hybrid,two hybrid ComPPI,HPRD,IntAct
CREBBP GAK 14525934 15752756 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
NTRK1 GAK 25348397 N/A physical interaction ComPPI
PICALM GAK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USO1 GAK 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TNK1 GAK 25348397 N/A physical interaction ComPPI
PHKG2 GAK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AXIN1 GAK 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
NUMB GAK 25348397 N/A physical interaction ComPPI
AP1M1 GAK 10887964 12010461 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
AP1M2 GAK 10887964 12010461 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RBM14 GAK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA5 GAK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AFAP1 GAK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SPTAN1 GAK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AP2A2 GAK 25348397 N/A physical interaction ComPPI
RABGEF1 GAK 25348397 N/A physical interaction ComPPI
CLTC GAK 12732633 14525934 24234451 25348397 26496610 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
AP2A1 GAK 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
EPS15 GAK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AP2B1 GAK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
STON2 GAK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
OCRL GAK 24234451 25107275 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CCNG1 GAK 14525934 25348397 9013862 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
TNK2 GAK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIDINS220 GAK 25348397 N/A physical interaction ComPPI
CDK5 GAK 14525934 25348397 9013862 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MYO6 GAK 25348397 N/A physical interaction ComPPI
PPM1B GAK 25348397 N/A physical interaction ComPPI
WNK1 GAK 25348397 N/A physical interaction ComPPI
SEC13 GAK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AP2M1 GAK 10887964 12010461 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TRIM25 GAK 25348397 N/A physical interaction ComPPI
GAK ALK 25348397 N/A physical interaction ComPPI
GAK ATP13A2 22645275 24234451 25348397 physical association anti tag coimmunoprecipitation,ubiquitin reconstruction,physical interaction ComPPI,IntAct
GAK APP 25348397 N/A physical interaction ComPPI
GAK LGR4 25348397 N/A physical interaction ComPPI
GAK DMWD 25348397 N/A physical interaction ComPPI
GAK STAMBP 25348397 N/A physical interaction ComPPI
GAK CAPZB 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
GAK CLTA 25348397 N/A physical interaction ComPPI
GAK CLTB 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK CPM 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK DBN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK SEC16A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK GTSE1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK GOLGB1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK HIP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK MYO1C 25348397 N/A physical interaction ComPPI
GAK PIK3C2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK CLTCL1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK HIP1R 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK XPR1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK SEC24C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK CLINT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK FEM1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK KIF3A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK SYNPO 25348397 N/A physical interaction ComPPI
GAK CEP162 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK AAK1 25348397 N/A physical interaction ComPPI
GAK EDRF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK PHGDH 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK CHMP4A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK LIMA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK PLXNA3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK BMP2K 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK STAMBPL1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK DENND1A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK ZNF106 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK INF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK PUS7L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK PARP10 25348397 N/A physical interaction ComPPI
GAK MISP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK ACTRT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK FAM83B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK FAM83H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GAK KCTD7 25348397 N/A physical interaction ComPPI
GAK C5AR2 25348397 N/A physical interaction ComPPI
GAK IARS2 25348397 N/A physical interaction ComPPI
GAK CLASRP 25348397 N/A physical interaction ComPPI
GAK FAM174A 25348397 N/A physical interaction ComPPI
GAK LRRK2 24234451 24510904 24947832 25348397 29513927 colocalization,association,physical association anti tag coimmunoprecipitation,protein array,fluorescence microscopy,confocal microscopy ComPPI,IntAct
GAK BAG5 24234451 24510904 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
GAK RAB29 24234451 24510904 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
GAK LRRK1 24234451 24947832 25348397 N/A protein array ComPPI,IntAct
GAK BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
GAK PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
GAK ICOS 24234451 25348397 27135603 association anti bait coimmunoprecipitation ComPPI,IntAct
GAK TGOLN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
GAK MFHAS1 24234451 25348397 29513927 N/A protein array ComPPI,IntAct
HSCB GAK 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
GAK CALM2 24234451 26496610 association anti tag coimmunoprecipitation IntAct

Visualization










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