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GENE：GOLPH3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GOLPH3
FullNmae golgi phosphoprotein 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15452
EnsembleID ENSG00000113384
Uniprot Q9H4A6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GOLPH3 pyroptosis 36334342 Our results represented that Ni fumes exposure evoked pyroptosis via GOLPH3 and induced oxidative stress, while, metformin treatment alleviated Ni particles-mediated above changes. retulator signature
GOLPH3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GOLPH3 GO:0000139,GO:0005515,GO:0005739,GO:0005758,GO:0005768,GO:0005794,GO:0005794,GO:0005802,GO:0005802,GO:0005829,GO:0005829,GO:0005886,GO:0006890,GO:0007030,GO:0007030,GO:0009101,GO:0009306,GO:0010467,GO:0010821,GO:0016477,GO:0019899,GO:0030032,GO:0031985,GO:0031985,GO:0032008,GO:0032580,GO:0043001,GO:0043001,GO:0043066,GO:0043231,GO:0045053,GO:0048194,GO:0048194,GO:0050714,GO:0050901,GO:0060352,GO:0070273,GO:0070273,GO:0072752,GO:0090161,GO:0090164

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR GOLPH3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 GOLPH3 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 GOLPH3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 GOLPH3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 GOLPH3 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 GOLPH3 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC GOLPH3 12747840 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 GOLPH3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GOLPH3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 GOLPH3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GOLPH3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GOLPH3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF GOLPH3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR GOLPH3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ATF1 GOLPH3 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 GOLPH3 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00005E6F45 GOLPH3 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002FF522 GOLPH3 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 GOLPH3 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004F24A9 GOLPH3 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000272A92 GOLPH3 25416803 28260021 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
PRKDC GOLPH3 22135298 phosphorylation N/A PhosphoSite
COPB1 GOLPH3 25361965 interaction type N/A PTMCode2
GOLPH3 COPB1 25361965 interaction type N/A PTMCode2
ARCN1 GOLPH3 25361965 interaction type N/A PTMCode2
GOLPH3 ARCN1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
DCUN1D1 GOLPH3 25348397 N/A physical interaction ComPPI
GOLPH3 ELAVL1 25348397 N/A physical interaction ComPPI
GOLPH3 ARL6IP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GOLPH3 PNKD 25348397 N/A physical interaction ComPPI
GOLPH3 P2RY12 25348397 N/A physical interaction ComPPI
GOLPH3 RASSF8 25348397 N/A physical interaction ComPPI
GOLPH3 GMPPB 25348397 N/A physical interaction ComPPI
GOLPH3 GMPPA 25348397 N/A physical interaction ComPPI
GOLPH3 RCC1L 25348397 N/A physical interaction ComPPI
GOLPH3 FAM20B 25348397 N/A physical interaction ComPPI
GOLPH3 TSR3 25348397 N/A physical interaction ComPPI
GOLPH3 DIPK2A 25348397 N/A physical interaction ComPPI
GOLPH3 AIMP1 25348397 N/A physical interaction ComPPI
GOLPH3 RANBP1 25348397 N/A physical interaction ComPPI
GOLPH3 PFDN4 25348397 N/A physical interaction ComPPI
GOLPH3 PFDN5 25348397 N/A physical interaction ComPPI
GOLPH3 RUVBL2 25348397 N/A physical interaction ComPPI
GOLPH3 SRM 25348397 N/A physical interaction ComPPI
GOLPH3 TIPRL 25348397 N/A physical interaction ComPPI
GOLPH3 VBP1 25348397 N/A physical interaction ComPPI
GOLPH3 NDUFA4 25348397 N/A physical interaction ComPPI
GOLPH3 COQ9 25348397 N/A physical interaction ComPPI
GOLPH3 NME4 25348397 N/A physical interaction ComPPI
GOLPH3 COQ8A 25348397 N/A physical interaction ComPPI
GOLPH3 NMES1 25348397 N/A physical interaction ComPPI
GOLPH3 SDHAF3 25348397 N/A physical interaction ComPPI
GOLPH3 COQ8B 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GOLPH3 DUSP9 25348397 N/A physical interaction ComPPI
GOLPH3 ST3GAL1 25348397 N/A physical interaction ComPPI
GOLPH3 AMIGO3 25348397 N/A physical interaction ComPPI
GOLPH3 GPRC5C 25348397 N/A physical interaction ComPPI
GOLPH3 C5AR2 25348397 N/A physical interaction ComPPI
GOLPH3 CHST6 25348397 N/A physical interaction ComPPI
GOLPH3 CHSY3 25348397 N/A physical interaction ComPPI
GOLPH3 SLC39A5 25348397 N/A physical interaction ComPPI
GOLPH3 P2RX1 25348397 N/A physical interaction ComPPI
GOLPH3 ENTPD7 25348397 N/A physical interaction ComPPI
GOLPH3 P2RY8 25348397 N/A physical interaction ComPPI
GOLPH3 TNFRSF8 25348397 N/A physical interaction ComPPI
GOLPH3 STEAP1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GOLPH3 TRIM25 25348397 N/A physical interaction ComPPI
GOLPH3 MYO18A 19837035 24234451 24485452 25348397 27898060 colocalization,physical association anti bait coimmunoprecipitation,pull down,fluorescence microscopy ComPPI,IntAct,OmniPath
GOLPH3 GCNT1 23027862 24234451 25348397 colocalization,physical association two hybrid,pull down,confocal microscopy ComPPI,IntAct
GOLPH3 PRKDC 24234451 24485452 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
GOLPH3 XRCC5 24234451 24485452 25348397 phosphorylation reaction,physical association anti bait coimmunoprecipitation,protein kinase assay ComPPI,IntAct
GOLPH3 XRCC6 24234451 24485452 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
GOLPH3 ESR2 24234451 25348397 25604459 association tandem affinity purification ComPPI,IntAct
GOLPH3 TGOLN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
GOLPH3 OCIAD1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
GOLPH3 NDUFAF4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
GOLPH3 COX6B1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
GOLPH3 NDUFAF8 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
GOLPH3 ADCK5 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
GOLPH3 ACP6 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
TNIP2 GOLPH3 24234451 30561431 association virotrap IntAct
ATF1 GOLPH3 12527906 27898060 stimulant N/A OmniPath
PRKDC GOLPH3 24485452 27898060 N/A N/A OmniPath

Visualization










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