Gene Information gene info

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GENE：GPNMB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GPNMB
FullNmae glycoprotein nmb
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4462
EnsembleID ENSG00000136235
Uniprot Q14956

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GPNMB mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GPNMB autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GPNMB GO:0001818,GO:0001934,GO:0005178,GO:0005515,GO:0005886,GO:0007155,GO:0007165,GO:0007267,GO:0008201,GO:0008285,GO:0016020,GO:0030335,GO:0031901,GO:0031954,GO:0032720,GO:0033162,GO:0034103,GO:0042056,GO:0042130,GO:0045545,GO:0045765,GO:0048018,GO:0050868,GO:0050918,GO:0070374,GO:2000134

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 GPNMB 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 GPNMB 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 GPNMB 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TP53 GPNMB 15684612 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
SMARCA4 GPNMB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GPNMB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GPNMB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GPNMB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 GPNMB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GPNMB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 GPNMB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF GPNMB 18971253 18983539 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 GPNMB 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 GPNMB 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000021202F GPNMB 25416803 27003587 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
SMAD4 GPNMB 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
GPNMB ITSN2 25348397 N/A physical interaction ComPPI
GPNMB IL31RA 25348397 N/A physical interaction ComPPI
GPNMB TFEB 25348397 N/A physical interaction ComPPI
GPNMB EGFR 24234451 25348397 26751287 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
GPNMB PTK6 24234451 25348397 26751287 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct

Source Target Pmid Interactiontype Methods Database
URS00009B1366 GPNMB 27087310 direct interaction,inhibition N/A NPInter

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