Gene Information gene info

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GENE：HHEX

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HHEX
FullNmae hematopoietically expressed homeobox
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4901
EnsembleID ENSG00000152804
Uniprot Q03014

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HHEX autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HHEX GO:0000122,GO:0000785,GO:0000976,GO:0000976,GO:0000978,GO:0000978,GO:0000981,GO:0001227,GO:0001228,GO:0005515,GO:0005634,GO:0005737,GO:0006357,GO:0006406,GO:0008190,GO:0008301,GO:0009952,GO:0010621,GO:0010944,GO:0016055,GO:0016525,GO:0016973,GO:0017025,GO:0030154,GO:0030154,GO:0030177,GO:0030183,GO:0030948,GO:0032993,GO:0034504,GO:0042803,GO:0043565,GO:0045736,GO:0045892,GO:0045893,GO:0045944,GO:0045944,GO:0070663,GO:0071103,GO:0090263,GO:0140297,GO:0140297

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HHEX hsa:3087 path:hsa04950 Maturity onset diabetes of the young - Homo sapiens (human)
HHEX hsa:3087 path:hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 HHEX 19374776 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
GATA1 HHEX 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 HHEX 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 HHEX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA HHEX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HHEX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 HHEX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HHEX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 HHEX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A HHEX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 HHEX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 HHEX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYB HHEX N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002C0FCB HHEX 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 HHEX 22135298 phosphorylation N/A PhosphoSite
HHEX GATA2 25361965 interaction type N/A PTMCode2
GATA2 HHEX 25361965 interaction type N/A PTMCode2
HHEX TLE1 25361965 interaction type N/A PTMCode2
TLE1 HHEX 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KRTAP10-5 HHEX 24234451 25348397 25416956 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KRTAP5-9 HHEX 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRTAP10-8 HHEX 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KRTAP4-12 HHEX 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
EFEMP2 HHEX 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
KRTAP2-3 HHEX 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRTAP10-7 HHEX 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HHEX JUN 11551904 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
HHEX PML 10597310 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
HHEX TLE1 14525934 15187083 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
HHEX SOX10 14525934 16582099 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
HHEX SOX8 14525934 16582099 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
HHEX GATA2 14525934 15016828 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
HHEX PSMA3 12826010 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
HHEX TRMT6 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HHEX KRTAP10-3 25348397 N/A physical interaction ComPPI
HHEX CDC27 25348397 N/A physical interaction ComPPI
HHEX ANAPC4 25348397 N/A physical interaction ComPPI
HHEX ANAPC10 25348397 N/A physical interaction ComPPI
HHEX CDC20 25348397 N/A physical interaction ComPPI
HHEX RAE1 25348397 N/A physical interaction ComPPI
HHEX FZR1 25348397 N/A physical interaction ComPPI
HHEX MDFI 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HHEX CYSRT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HHEX PFDN5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HHEX KHDRBS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HHEX KRTAP19-1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HHEX NOTCH2NLA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HHEX KRTAP6-2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HHEX RBMY1F 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HHEX KRTAP10-6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HHEX KRTAP5-8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HHEX PSTPIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HHEX KRTAP6-1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HHEX KRTAP5-7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
APOBEC3C HHEX 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GATA6 HHEX 14525934 15016828 N/A two hybrid HPRD
CSNK2A1 HHEX 19324893 27898060 N/A N/A OmniPath

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