Gene Information gene info

  1. Home

GENE：RFC1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RFC1
FullNmae replication factor C subunit 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9969
EnsembleID ENSG00000035928
Uniprot P35251

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RFC1 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RFC1 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RFC1 GO:0000122,GO:0003677,GO:0003689,GO:0003690,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005654,GO:0005663,GO:0005663,GO:0006261,GO:0006281,GO:0007004,GO:0008047,GO:0016887,GO:0019904,GO:0031391,GO:0043565,GO:0045893,GO:0061860,GO:0061860,GO:0070062,GO:0090618

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RFC1 hsa:5981 path:hsa03030 DNA replication - Homo sapiens (human)
RFC1 hsa:5981 path:hsa03410 Base excision repair - Homo sapiens (human)
RFC1 hsa:5981 path:hsa03420 Nucleotide excision repair - Homo sapiens (human)
RFC1 hsa:5981 path:hsa03430 Mismatch repair - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RFC1 RFC2 14624239 26192618 interaction type N/A ACSN
RFC1 RFC3 14624239 26192618 interaction type N/A ACSN
RFC1 RFC5 14624239 26192618 interaction type N/A ACSN
RFC4 RFC1 14624239 26192618 interaction type N/A ACSN
RFC1 PCNA 26192618 interaction type N/A ACSN

Source Target Pmid Interactiontype Methods Database
AR RFC1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 RFC1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 RFC1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 RFC1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 RFC1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 RFC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RFC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 RFC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RFC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RFC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RFC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RFC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RFC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 RFC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000005481D RFC1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000153377 RFC1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CDK1 RFC1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
DAXX RFC1 25348397 N/A physical interaction ComPPI
PCNA RFC1 12045192 12171929 14525934 25348397 8861969 8999859 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CCND1 RFC1 10353443 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
GABARAPL2 RFC1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
H2BC4 RFC1 25348397 N/A physical interaction ComPPI
KEAP1 RFC1 25348397 N/A physical interaction ComPPI
NIFK RFC1 25348397 N/A physical interaction ComPPI
GLYR1 RFC1 25348397 N/A physical interaction ComPPI
EMC2 RFC1 25348397 N/A physical interaction ComPPI
NF2 RFC1 25348397 N/A physical interaction ComPPI
RACGAP1 RFC1 25348397 N/A physical interaction ComPPI
FGF3 RFC1 25348397 N/A physical interaction ComPPI
NOTCH1 RFC1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CASP3 RFC1 14525934 25348397 9235961 9351817 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
JUN RFC1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
RB1 RFC1 11336696 25348397 27898060 N/A physical interaction ComPPI,OmniPath
RPL18A RFC1 25348397 N/A physical interaction ComPPI
UBC RFC1 25348397 N/A physical interaction ComPPI
NTRK1 RFC1 25348397 N/A physical interaction ComPPI
YBX1 RFC1 24234451 25348397 25497084 association anti bait coimmunoprecipitation ComPPI,IntAct
XRCC5 RFC1 25348397 N/A physical interaction ComPPI
RBM14 RFC1 25348397 N/A physical interaction ComPPI
RPA1 RFC1 25348397 N/A physical interaction ComPPI
RFC2 RFC1 14525934 15655353 24234451 25348397 9488738 association,physical association coimmunoprecipitation,cosedimentation in solution,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
MSH6 RFC1 25348397 N/A physical interaction ComPPI
CHTF18 RFC1 25348397 N/A physical interaction ComPPI
MYC RFC1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HNRNPU RFC1 25348397 N/A physical interaction ComPPI
XRCC6 RFC1 25348397 N/A physical interaction ComPPI
RELA RFC1 12509469 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
BLM RFC1 25348397 N/A physical interaction ComPPI
ATM RFC1 25348397 N/A physical interaction ComPPI
RPA2 RFC1 25348397 N/A physical interaction ComPPI
RPA3 RFC1 25348397 N/A physical interaction ComPPI
YWHAQ RFC1 25348397 N/A physical interaction ComPPI
RPS6 RFC1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SMC1A RFC1 14525934 16438930 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
THBS3 RFC1 25348397 N/A physical interaction ComPPI
LAMP2 RFC1 25348397 N/A physical interaction ComPPI
H3C1 RFC1 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
IBTK RFC1 25348397 N/A physical interaction ComPPI
CDC45 RFC1 25348397 N/A physical interaction ComPPI
RFC5 RFC1 24234451 25348397 9488738 association,physical association cosedimentation in solution,pull down,physical interaction ComPPI,IntAct
NOP56 RFC1 25348397 N/A physical interaction ComPPI
MRE11 RFC1 25348397 N/A physical interaction ComPPI
NBN RFC1 25348397 N/A physical interaction ComPPI
RAD50 RFC1 25348397 N/A physical interaction ComPPI
CDK4 RFC1 10353443 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RFC4 RFC1 24234451 25348397 9488738 association,physical association cosedimentation in solution,pull down,physical interaction ComPPI,IntAct
ESR2 RFC1 21182203 24234451 25348397 association cosedimentation through density gradient ComPPI,IntAct
RFC3 RFC1 14525934 24234451 25348397 8692848 9488738 association,physical association cosedimentation in solution,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
RAD17 RFC1 25348397 N/A physical interaction ComPPI
BRCA1 RFC1 10783165 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
MLH1 RFC1 25348397 N/A physical interaction ComPPI
BRD4 RFC1 12192049 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MYOC RFC1 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
TEAD2 RFC1 25348397 N/A physical interaction ComPPI
AURKAIP1 RFC1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RFC1 CEBPA 12509469 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RFC1 TCEAL1 10353443 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RFC1 MSH2 25348397 N/A physical interaction ComPPI
RFC1 HDAC1 12045192 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
RFC1 TP53 25348397 N/A physical interaction ComPPI
RFC1 PMS1 25348397 N/A physical interaction ComPPI
RFC1 SSBP3 25348397 N/A physical interaction ComPPI
RFC1 ZSCAN1 25348397 N/A physical interaction ComPPI
RFC1 SAP25 25348397 N/A physical interaction ComPPI
RFC1 CSNK2B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RFC1 HDGF 21907836 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
RFC1 SIRT7 25348397 N/A physical interaction ComPPI
RFC1 WDR18 25348397 N/A physical interaction ComPPI
RFC1 SPRTN 25348397 N/A physical interaction ComPPI
RFC1 THBS4 25348397 N/A physical interaction ComPPI
RFC1 PDS5A 25348397 N/A physical interaction ComPPI
RFC1 SMC2 25348397 N/A physical interaction ComPPI
RFC1 SMC4 25348397 N/A physical interaction ComPPI
RFC1 H2BC11 25348397 N/A physical interaction ComPPI
RFC1 LCOR 25348397 N/A physical interaction ComPPI
RFC1 MACROH2A2 25348397 N/A physical interaction ComPPI
RFC1 RRP8 25348397 N/A physical interaction ComPPI
RFC1 E2F3 22157815 24234451 25348397 association pull down ComPPI,IntAct
RFC1 FBL 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RFC1 RFC1 12192049 14525934 N/A experimental interaction detection HPRD
RFC1 OXR1 24234451 30021884 physical association cross-linking study IntAct
CDK1 RFC1 12930972 27898060 N/A N/A OmniPath

Visualization










  Return