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GENE：IP6K1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IP6K1
FullNmae inositol hexakisphosphate kinase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18360
EnsembleID ENSG00000176095
Uniprot Q92551

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IP6K1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
IP6K1 GO:0000827,GO:0000828,GO:0000828,GO:0000828,GO:0000829,GO:0000832,GO:0001650,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0016310,GO:0032958,GO:0043647,GO:0046854,GO:0046854,GO:0052723,GO:0052724,GO:0052836,GO:0052839,GO:0120163

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
IP6K1 hsa:9807 path:hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 IP6K1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 IP6K1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A IP6K1 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
YBX1 IP6K1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 IP6K1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA IP6K1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 IP6K1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 IP6K1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS IP6K1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A IP6K1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 IP6K1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 IP6K1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000070B1D IP6K1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EC1BE IP6K1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001F0C23 IP6K1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000DDD35 IP6K1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000031E12 IP6K1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 IP6K1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002E728C IP6K1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005F9738 IP6K1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003D5391 IP6K1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D IP6K1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000585553 IP6K1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005F1B8C IP6K1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002578DA IP6K1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000000C73C IP6K1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00006097A6 IP6K1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002367FA IP6K1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 IP6K1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000334286 IP6K1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001CE046 IP6K1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA IP6K1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075B0F6 IP6K1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001310DE IP6K1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000058DCD8 IP6K1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000081D1E IP6K1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000CF1D2 IP6K1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000353492 IP6K1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000002103A IP6K1 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075A608 IP6K1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075E2C3 IP6K1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000170D8B IP6K1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000239117 IP6K1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0874 IP6K1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000083D87 IP6K1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA IP6K1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075ABF4 IP6K1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000057A7C IP6K1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000060AABB IP6K1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002152A8 IP6K1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000148B91 IP6K1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000171020 IP6K1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075A760 IP6K1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001481F9 IP6K1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075D15B IP6K1 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
VIM IP6K1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PICK1 IP6K1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FGFR2 IP6K1 25348397 N/A physical interaction ComPPI
RBX1 IP6K1 25348397 N/A physical interaction ComPPI
CANX IP6K1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CLK1 IP6K1 25348397 N/A physical interaction ComPPI
COPS2 IP6K1 25348397 N/A physical interaction ComPPI
CUL4A IP6K1 25348397 N/A physical interaction ComPPI
CACNA1A IP6K1 21078624 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TFCP2 IP6K1 25348397 N/A physical interaction ComPPI
GPS1 IP6K1 25348397 N/A physical interaction ComPPI
TRIM25 IP6K1 25348397 N/A physical interaction ComPPI
DDB1 IP6K1 25348397 N/A physical interaction ComPPI
EXOSC7 IP6K1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
DEFA5 IP6K1 25348397 N/A physical interaction ComPPI
IP6K1 UBE4A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DEFA6 IP6K1 25348397 N/A physical interaction ComPPI

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