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GENE：IP6K2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IP6K2
FullNmae inositol hexakisphosphate kinase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17313
EnsembleID ENSG00000068745
Uniprot Q9UHH9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IP6K2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
IP6K2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
IP6K2 GO:0000827,GO:0000828,GO:0000828,GO:0000828,GO:0000829,GO:0000832,GO:0001650,GO:0005515,GO:0005524,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0016310,GO:0030054,GO:0030308,GO:0032958,GO:0033138,GO:0043065,GO:0043647,GO:0043647,GO:0046854,GO:0046854,GO:0050821,GO:0052836,GO:0052839,GO:0097243,GO:1905396

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
IP6K2 hsa:51447 path:hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IP6K2 TRAF2 17379600 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR IP6K2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 IP6K2 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 IP6K2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 IP6K2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 IP6K2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 IP6K2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF IP6K2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 IP6K2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS IP6K2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A IP6K2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 IP6K2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 IP6K2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00001F0C23 IP6K2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000035CC3E IP6K2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000D0BB4 IP6K2 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A IP6K2 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000CF1D2 IP6K2 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 IP6K2 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF IP6K2 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 IP6K2 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
RBPMS IP6K2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MEOX2 IP6K2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HSP90AB1 IP6K2 25348397 N/A physical interaction ComPPI
PLOD3 IP6K2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PLSCR1 IP6K2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
UBB IP6K2 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
UBC IP6K2 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
RPS27A IP6K2 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
UBA52 IP6K2 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
HSP90AA1 IP6K2 18195352 24234451 25348397 27898060 N/A anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct,OmniPath
GABRR1 IP6K2 25348397 N/A physical interaction ComPPI
TRAF2 IP6K2 25348397 N/A physical interaction ComPPI
TRIM25 IP6K2 25348397 N/A physical interaction ComPPI
LNX2 IP6K2 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RHOU IP6K2 25348397 N/A physical interaction ComPPI
IP6K2 HSP90AA2P 25348397 N/A physical interaction ComPPI
IP6K2 GTPBP6 25348397 N/A physical interaction ComPPI
IP6K2 UNK 25348397 N/A physical interaction ComPPI
IP6K2 PGK2 25348397 N/A physical interaction ComPPI
IP6K2 TP53 21078964 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct,OmniPath
IP6K2 ZBTB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCT6A IP6K2 24234451 30021884 physical association cross-linking study IntAct
IP6K2 TRAF2 17379600 27898060 N/A N/A OmniPath
CSNK2A1 IP6K2 21262846 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009AEA7A IP6K2 27087310 direct interaction,inhibition N/A NPInter

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