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GENE：IRF1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IRF1
FullNmae interferon regulatory factor 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6116
EnsembleID ENSG00000125347
Uniprot P10914

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IRF1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
IRF1 pyroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
IRF1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
IRF1 GO:0000785,GO:0000785,GO:0000976,GO:0000977,GO:0000978,GO:0000978,GO:0000978,GO:0000981,GO:0000981,GO:0000981,GO:0001228,GO:0001228,GO:0002376,GO:0002819,GO:0003677,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006357,GO:0006366,GO:0006915,GO:0008285,GO:0032481,GO:0032728,GO:0032735,GO:0034124,GO:0035458,GO:0043374,GO:0045088,GO:0045590,GO:0045892,GO:0045893,GO:0045893,GO:0045944,GO:0045944,GO:0051607,GO:0051726,GO:0051726,GO:0060333,GO:0071260,GO:2000564

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
IRF1 hsa:3659 path:hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human)
IRF1 hsa:3659 path:hsa04668 TNF signaling pathway - Homo sapiens (human)
IRF1 hsa:3659 path:hsa04917 Prolactin signaling pathway - Homo sapiens (human)
IRF1 hsa:3659 path:hsa05133 Pertussis - Homo sapiens (human)
IRF1 hsa:3659 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IRF1 CIITA 10485906 10820262 11399519 11875494 12417340 12433365 15644117 16127449 16597464 17260466 17689680 18345002 21097505 22461508 23390297 26192618 6357187 8871614 interaction type N/A ACSN
IRF1 NOS2 10485906 10820262 11399519 11875494 12417340 12433365 15644117 16127449 16597464 17260466 17689680 18345002 21097505 22461508 23390297 26192618 6357187 8871614 interaction type N/A ACSN
IRF1 MMP9 10485906 10820262 11399519 11875494 12105194 12417340 12433365 15644117 16127449 16597464 17260466 17689680 18345002 21097505 22461508 23180781 23390297 26192618 6357187 8871614 interaction type,physical association electrophoretic mobility supershift assay ACSN,InnateDB
TNF IRF1 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23180781 23430059 23508573 23510023 23567181 23769623 23850759 24012417 24092389 24378531 24699077 24958845 26192618 26201938 8910423 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
TRAF1 IRF1 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 8910423 interaction type N/A ACSN
TRAF2 IRF1 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 8910423 interaction type N/A ACSN
STAT1 IRF1 10485906 10754326 10820262 10921891 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23180781 23390297 24012417 25960930 26192618 6357187 7594497 8683106 8871614 interaction type,physical association affinity chromatography technology,anti tag coimmunoprecipitation ACSN,InnateDB
IRF1 SOCS1 10485906 10820262 11399519 11875494 12417340 12433365 15644117 16127449 16597464 17260466 17689680 18345002 21097505 22461508 23390297 26192618 6357187 8871614 interaction type N/A ACSN
IRF1 MYC 10485906 10820262 11399519 11875494 12417340 12433365 15644117 16127449 16597464 17260466 17689680 18345002 21097505 22461508 23390297 26192618 6357187 8871614 interaction type N/A ACSN
MYD88 IRF1 17018642 23180781 physical association anti tag coimmunoprecipitation,fluorescent resonance energy transfer InnateDB
IRF1 CASP8 14993214 17036321 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
ISG20 IRF1 15064705 23180781 physical association affinity chromatography technology InnateDB
EP300 IRF1 12939262 15509808 21220691 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation InnateDB
IRF1 IFNB1 11090630 12077266 15494505 1579446 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
B2M IRF1 12480693 23180781 physical association electrophoretic mobility supershift assay,electrophoretic mobility shift assay InnateDB
CXCL8 IRF1 15057743 18198374 23180781 physical association affinity chromatography technology,electrophoretic mobility supershift assay InnateDB
IRF1 STAT1 10725732 10764778 10925286 11601909 11777927 11882993 11909852 12077266 12115600 12654826 14578356 14581002 15107292 15194680 16195385 16512786 16785527 17016442 17918184 18678606 19136629 19482358 21516110 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
IRF1 STAT3 11882993 14578356 17182572 17918184 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
IRF7 IRF1 10924517 12077266 14578356 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
IRF1 IL4 12479817 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
IRF1 MYB 10739671 23180781 physical association electrophoretic mobility supershift assay InnateDB
CIITA IRF1 10557076 11675374 12052885 12493643 12788988 15950283 16195385 16982896 17300840 18500344 23180781 9916712 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
IRF1 HLA-G 11087747 23180781 physical association electrophoretic mobility supershift assay InnateDB
IRF1 OGN 12835654 23180781 physical association electrophoretic mobility supershift assay InnateDB
PSMB10 IRF1 10575004 18694960 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
IRF1 GTF2B 23180781 8887661 physical association gst pull down,electrophoretic mobility shift assay InnateDB
IRF1 KAT2A 10022868 23180781 physical association affinity chromatography technology,pull down InnateDB
IRF1 OAS1 10319996 23180781 physical association electrophoretic mobility supershift assay InnateDB
NFKB1 IRF1 10319996 11342638 12077266 15078941 23180781 physical association affinity chromatography technology,electrophoretic mobility supershift assay InnateDB
IRF1 RELA 10319996 12115600 15078941 18216101 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
SUB1 IRF1 15893730 23180781 physical association anti tag coimmunoprecipitation InnateDB
CSNK2A1 IRF1 15893730 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 CSNK2B 15893730 23180781 physical association anti tag coimmunoprecipitation InnateDB
MED10 IRF1 15893730 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 MED23 15893730 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 TBP 15893730 23180781 physical association anti tag coimmunoprecipitation InnateDB
GTF2F1 IRF1 15893730 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 ERCC3 15893730 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 DR1 15893730 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 DRAP1 15893730 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 IL18BP 12482935 23180781 physical association electrophoretic mobility supershift assay InnateDB
IRF1 CEBPB 12482935 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
IL7 IRF1 15226432 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
IRF1 CYBB 11781315 23180781 8798551 9593745 physical association electrophoretic mobility supershift assay,electrophoretic mobility shift assay InnateDB
CREBBP IRF1 17016442 23180781 9659924 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
IRF1 NCF2 10570299 23180781 physical association electrophoretic mobility shift assay InnateDB
IRF1 SPI1 11483597 23180781 9593745 physical association anti tag coimmunoprecipitation,pull down,electrophoretic mobility shift assay InnateDB
IRF1 IRF8 10570299 11483597 23180781 7768900 9593745 physical association anti tag coimmunoprecipitation,pull down,electrophoretic mobility supershift assay,electrophoretic mobility shift assay InnateDB
SPI1 IRF1 23180781 9593745 physical association pull down InnateDB
PTPN6 IRF1 11483597 23180781 dephosphorylation reaction in gel phosphatase assay InnateDB
IRF1 AR 17011549 23180781 physical association anti tag coimmunoprecipitation InnateDB
SOCS1 IRF1 15545275 19482358 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
IRF1 CCL19 17182562 23180781 physical association affinity chromatography technology InnateDB
IRF1 IL12A 14568984 15489234 18316378 19164128 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation InnateDB
IRF1 KPNA2 17255955 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 PSMB8 15907481 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL10 IRF1 16253303 17167270 18986693 23180781 9794404 physical association affinity chromatography technology,electrophoretic mobility supershift assay InnateDB
IRF1 UPK2 18688264 23180781 physical association electrophoretic mobility supershift assay InnateDB
CELSR3 IRF1 18655181 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
IRF1 TAP1 11059775 15778351 16982896 18694960 23180781 8617938 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
IRF1 TAP2 18694960 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 TAPBP 18694960 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 TNFSF10 15241475 17617740 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
CD38 IRF1 17947510 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL27 IRF1 17985330 23180781 physical association electrophoretic mobility supershift assay InnateDB
IRF1 DDX58 17516545 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
IRF1 IRF2 10557076 15241475 23180781 8943426 physical association electrophoretic mobility supershift assay InnateDB
IRF1 CTSS 11970993 23180781 physical association electrophoretic mobility supershift assay InnateDB
IRF1 NR3C1 15576464 23180781 physical association electrophoretic mobility supershift assay InnateDB
IRF1 TRAF3IP2 12759449 23180781 physical association electrophoretic mobility supershift assay InnateDB
IRF1 VCAM1 12115600 15265939 18490752 23180781 physical association electrophoretic mobility supershift assay InnateDB
IRF1 IFI6 15467738 17016442 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 TLR3 12672806 21220691 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
IRF1 IL2RA 12244150 23180781 physical association electrophoretic mobility supershift assay InnateDB
IRF1 DST 15560761 23180781 physical association electrophoretic mobility supershift assay InnateDB
MYH9 IRF1 15496418 23180781 physical association electrophoretic mobility supershift assay InnateDB
ERAP2 IRF1 15691326 23180781 physical association electrophoretic mobility supershift assay InnateDB
COL1A2 IRF1 16091368 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 GBP1 10557076 23180781 physical association electrophoretic mobility supershift assay InnateDB
IRF1 CD200 19386363 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 IFNA1 11473119 12077266 23180781 physical association affinity chromatography technology,electrophoretic mobility supershift assay InnateDB
IRF5 IRF1 12600985 23180781 physical association pull down InnateDB
IRF1 IFNL1 17785777 21398614 23180781 physical association affinity chromatography technology,pull down InnateDB
IRF1 IFNL3 17785777 23180781 physical association affinity chromatography technology InnateDB
IRF1 ISG15 12654826 23180781 8943426 physical association electrophoretic mobility supershift assay InnateDB
STAT2 IRF1 15668228 23180781 physical association anti tag coimmunoprecipitation InnateDB
EVL IRF1 19151778 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 IRF9 12654826 23180781 physical association electrophoretic mobility supershift assay InnateDB
IRF1 FOXP3 18641303 23180781 physical association affinity chromatography technology InnateDB
CXCL11 IRF1 17202361 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 STAT4 10358173 21516110 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
IRF1 IFNA2 11473119 23180781 physical association affinity chromatography technology InnateDB
SMARCA4 IRF1 17182572 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 IFNA14 15699120 23180781 physical association affinity chromatography technology InnateDB
IRF1 IFNGR1 16785527 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
IRF1 IFNG 16785527 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
TRIM44 IRF1 20421211 23180781 physical association anti tag coimmunoprecipitation InnateDB
GLI3 IRF1 20421211 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 SP110 20421211 23180781 physical association anti tag coimmunoprecipitation InnateDB
NFIX IRF1 20421211 23180781 physical association anti tag coimmunoprecipitation InnateDB
STAT6 IRF1 20421211 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 AIM2 20421211 23180781 physical association anti tag coimmunoprecipitation InnateDB
LMO2 IRF1 20421211 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 BTN3A3 20421211 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL21R IRF1 19617351 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 STAT5A 21516110 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 STAT5B 21516110 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 CXCR4 21447649 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 TRMT2A 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 TRAF3 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 KEAP1 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 HCFC1 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 SEC63 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 NPM1 21245151 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 TRIM28 21245151 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF1 YBX1 21245151 23180781 physical association anti tag coimmunoprecipitation InnateDB
CCL5 IRF1 12388374 23180781 physical association affinity chromatography technology,electrophoretic mobility supershift assay InnateDB
IKBKE IRF1 23180781 24396068 phosphorylation reaction protein kinase assay InnateDB
IL6 IRF1 23180781 24012417 physical association anti tag coimmunoprecipitation InnateDB
IL12B IRF1 23180781 24012417 physical association anti tag coimmunoprecipitation InnateDB
RELA IRF1 23180781 24396068 physical association anti tag coimmunoprecipitation InnateDB
TRAF6 IRF1 23180781 24464131 physical association anti tag coimmunoprecipitation InnateDB
TBX21 IRF1 23180781 23232398 physical association anti tag coimmunoprecipitation InnateDB
GATA3 IRF1 23180781 23232398 physical association anti tag coimmunoprecipitation InnateDB
IRF1 CD83 23180781 23339870 physical association electrophoretic mobility supershift assay InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 IRF1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 IRF1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 IRF1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
STAT1 IRF1 10068671 10764778 12077266 18401423 18497060 18694960 22002246 24478085 8647845 trascriptional regulation,stimulation affinity chromatography technology,inferred by curator,electrophoretic mobility shift assay TFlink
STAT2 IRF1 8647845 trascriptional regulation,stimulation affinity chromatography technology,inferred by curator,electrophoretic mobility shift assay TFlink
STAT3 IRF1 10068671 18971253 8647845 trascriptional regulation,stimulation inferred by curator TFlink
SMARCA4 IRF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF IRF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 IRF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 IRF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 IRF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 IRF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS IRF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A IRF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 IRF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CIITA IRF1 12052885 15950283 trascriptional regulation,stimulation inferred by curator TFlink
CREBBP IRF1 18497060 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 IRF1 12077266 18694960 trascriptional regulation,stimulation inferred by curator TFlink
RELA IRF1 12077266 18694960 trascriptional regulation,stimulation inferred by curator TFlink
STAT4 IRF1 10068671 10358173 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000C5969 IRF1 21368870 rna interference,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00000C5969 IRF1 21368870 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000DDD35 IRF1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00001C3AC1 IRF1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001CC864 IRF1 23785404 25416803 27279136 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000451A1 IRF1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000005CE28 IRF1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEF5F IRF1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 IRF1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 IRF1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 IRF1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA IRF1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 IRF1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 IRF1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A IRF1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B IRF1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC IRF1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB IRF1 23824327 25416803 25617495 mrna cleavage,inhibition quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS0000315338 IRF1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000367985 IRF1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000AA464 IRF1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000544FF1 IRF1 25416803 27866197 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
IKBKE IRF1 22135298 phosphorylation N/A PhosphoSite
IRF1 KAT2B 25361965 interaction type N/A PTMCode2
KAT2B IRF1 25361965 interaction type N/A PTMCode2
IRF1 IRF8 25361965 interaction type N/A PTMCode2
IRF8 IRF1 25361965 interaction type N/A PTMCode2
IRF1 HMGA1 25361965 interaction type N/A PTMCode2
HMGA1 IRF1 25361965 interaction type N/A PTMCode2
IRF1 SUMO1 25361965 interaction type N/A PTMCode2
SUMO1 IRF1 25361965 interaction type N/A PTMCode2
IRF1 RELA 25361965 interaction type N/A PTMCode2
RELA IRF1 25361965 interaction type N/A PTMCode2
NFKB1 IRF1 25361965 interaction type N/A PTMCode2
IRF1 NFKB1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NPM1 IRF1 25348397 N/A physical interaction ComPPI
STAT1 IRF1 10764778 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CDKN1B IRF1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SET IRF1 25348397 N/A physical interaction ComPPI
KEAP1 IRF1 25348397 N/A physical interaction ComPPI
CBL IRF1 25348397 N/A physical interaction ComPPI
SPI1 IRF1 25348397 N/A physical interaction ComPPI
HCFC1 IRF1 25348397 N/A physical interaction ComPPI
CREBBP IRF1 25348397 N/A physical interaction ComPPI
HMGA1 IRF1 10357819 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SUMO1 IRF1 17942705 24234451 25348397 covalent binding,physical association anti bait coimmunoprecipitation,covalent binding,physical interaction,comigration in sds page ComPPI,IntAct
EP300 IRF1 10438822 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
IRF8 IRF1 14525934 25348397 7768900 9742224 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
KAT2B IRF1 10022868 11304541 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
UBB IRF1 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
UBC IRF1 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
RPS27A IRF1 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
UBA52 IRF1 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
HSP90AA1 IRF1 25348397 N/A physical interaction ComPPI
YBX1 IRF1 25348397 N/A physical interaction ComPPI
SMARCA4 IRF1 25348397 N/A physical interaction ComPPI
HSPA1A IRF1 25348397 N/A physical interaction ComPPI
HSPA1B IRF1 25348397 N/A physical interaction ComPPI
TRAF3 IRF1 25348397 N/A physical interaction ComPPI
RELA IRF1 14525934 25348397 8746784 N/A experimental interaction detection,in vivo ComPPI,HPRD
QARS1 IRF1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MDM2 IRF1 23134341 24583282 24721577 25348397 27898060 N/A physical interaction ComPPI,OmniPath
TRIM28 IRF1 25348397 N/A physical interaction ComPPI
SP2 IRF1 25348397 N/A physical interaction ComPPI
KAT2A IRF1 25348397 N/A physical interaction ComPPI
H3C1 IRF1 25348397 N/A physical interaction ComPPI
NFKB1 IRF1 14525934 25348397 8746784 N/A experimental interaction detection,in vitro ComPPI,HPRD
PRDM1 IRF1 25348397 N/A physical interaction ComPPI
BIRC3 IRF1 25348397 N/A physical interaction ComPPI
STUB1 IRF1 20947504 23134341 23729439 25348397 26330542 27898060 N/A physical interaction ComPPI,OmniPath
SEC63 IRF1 25348397 N/A physical interaction ComPPI
IRF2 IRF1 25348397 N/A physical interaction ComPPI
ULK2 IRF1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
IRF1 IRF9 25348397 N/A physical interaction ComPPI
IRF1 TRMT2A 25348397 N/A physical interaction ComPPI
IRF1 HSP90AA2P 25348397 N/A physical interaction ComPPI
NCL IRF1 24234451 30021884 physical association cross-linking study IntAct
IRF1 PIAS3 12387893 27898060 N/A N/A OmniPath
IRF1 CEBPB 12482935 27898060 N/A N/A OmniPath
IRF1 TAT 12021315 27898060 N/A N/A OmniPath
IRF1 PCNA 19129219 27898060 stimulant N/A OmniPath
IKBKE IRF1 24396068 27898060 N/A N/A OmniPath
MYD88 IRF1 17018642 27898060 N/A N/A OmniPath
PTPN6 IRF1 11483597 27898060 N/A N/A OmniPath
IRF1 STAT1 10764778 16512786 24012417 27898060 N/A N/A OmniPath
STAT1 IRF1 10764778 16512786 17918184 24012417 27898060 stimulant N/A OmniPath
KPNA2 IRF1 17255955 27898060 stimulant N/A OmniPath
IRF1 H2BC5 19129219 27898060 stimulant N/A OmniPath
IRF1 IRF8 10570299 11483597 27898060 7768900 9742224 stimulant N/A OmniPath
CREBBP IRF1 17016442 27898060 9659924 stimulant N/A OmniPath
IRF5 IRF1 12600985 27898060 N/A N/A OmniPath
IRF1 CASP8 14993214 19129219 27898060 stimulant N/A OmniPath
IRF1 RELA 18216101 24396068 27898060 8746784 N/A N/A OmniPath
IRF1 EP300 10438822 14662860 15509808 21220691 23670564 27898060 N/A N/A OmniPath
EP300 IRF1 10438822 14662860 15509808 21220691 23670564 27898060 stimulant N/A OmniPath
IRF1 TNFSF10 19129219 27898060 stimulant N/A OmniPath
IRF1 NOS2 27898060 9988718 stimulant N/A OmniPath
IRF1 TRAF3 21903422 27898060 N/A N/A OmniPath
IRF1 ISG20 15064705 27898060 stimulant N/A OmniPath
IRF1 BRIP1 19129219 27898060 stimulant N/A OmniPath
IRF1 IRF9 12654826 12799427 20211142 27898060 N/A N/A OmniPath
SP2 IRF1 19482358 27898060 stimulant N/A OmniPath

Visualization










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