GENE：ITGB3
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ITGB3 |
| FullNmae | integrin subunit beta 3 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:6156 |
| EnsembleID | ENSG00000259207 |
| Uniprot | P05106 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ITGB3 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ITGB3 | GO:0001618,GO:0001934,GO:0001938,GO:0001954,GO:0001968,GO:0001968,GO:0002020,GO:0003756,GO:0005080,GO:0005161,GO:0005178,GO:0005178,GO:0005515,GO:0005634,GO:0005654,GO:0005886,GO:0005886,GO:0005911,GO:0005925,GO:0005925,GO:0005925,GO:0007044,GO:0007155,GO:0007160,GO:0007160,GO:0007229,GO:0007229,GO:0007229,GO:0007566,GO:0007596,GO:0008305,GO:0008305,GO:0009897,GO:0009986,GO:0009986,GO:0009986,GO:0010595,GO:0010628,GO:0010745,GO:0010763,GO:0010888,GO:0014823,GO:0014909,GO:0014911,GO:0015026,GO:0016324,GO:0016477,GO:0017134,GO:0019899,GO:0019960,GO:0030168,GO:0030949,GO:0031092,GO:0031258,GO:0031527,GO:0031528,GO:0031589,GO:0031994,GO:0032147,GO:0032369,GO:0032587,GO:0032880,GO:0032956,GO:0032991,GO:0033627,GO:0033627,GO:0033630,GO:0033690,GO:0034113,GO:0034446,GO:0034683,GO:0035295,GO:0035866,GO:0035867,GO:0035868,GO:0036120,GO:0038027,GO:0038132,GO:0042060,GO:0042470,GO:0042802,GO:0043184,GO:0043184,GO:0043235,GO:0043277,GO:0045124,GO:0045202,GO:0045211,GO:0045766,GO:0045780,GO:0046718,GO:0046872,GO:0048008,GO:0048146,GO:0048333,GO:0048661,GO:0050731,GO:0050748,GO:0050839,GO:0050840,GO:0050919,GO:0051279,GO:0051611,GO:0060055,GO:0070051,GO:0070062,GO:0070374,GO:0070527,GO:0071062,GO:0071133,GO:0071260,GO:0071466,GO:0072126,GO:0072378,GO:0098690,GO:0098880,GO:0098978,GO:0098978,GO:0098978,GO:0099149,GO:0099149,GO:0099149,GO:0150054,GO:1900026,GO:1900731,GO:1901163,GO:1903053,GO:1905598,GO:1990314,GO:2000352,GO:2000406 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| ITGB3 | hsa:3690 | path:hsa03266 | Virion - Herpesvirus - Homo sapiens (human) |
| ITGB3 | hsa:3690 | path:hsa04015 | Rap1 signaling pathway - Homo sapiens (human) |
| ITGB3 | hsa:3690 | path:hsa04145 | Phagosome - Homo sapiens (human) |
| ITGB3 | hsa:3690 | path:hsa04148 | Efferocytosis - Homo sapiens (human) |
| ITGB3 | hsa:3690 | path:hsa04151 | PI3K-Akt signaling pathway - Homo sapiens (human) |
| ITGB3 | hsa:3690 | path:hsa04380 | Osteoclast differentiation - Homo sapiens (human) |
| ITGB3 | hsa:3690 | path:hsa04510 | Focal adhesion - Homo sapiens (human) |
| ITGB3 | hsa:3690 | path:hsa04512 | ECM-receptor interaction - Homo sapiens (human) |
| ITGB3 | hsa:3690 | path:hsa04611 | Platelet activation - Homo sapiens (human) |
| ITGB3 | hsa:3690 | path:hsa04613 | Neutrophil extracellular trap formation - Homo sapiens (human) |
| ITGB3 | hsa:3690 | path:hsa04640 | Hematopoietic cell lineage - Homo sapiens (human) |
| ITGB3 | hsa:3690 | path:hsa04810 | Regulation of actin cytoskeleton - Homo sapiens (human) |
| ITGB3 | hsa:3690 | path:hsa04919 | Thyroid hormone signaling pathway - Homo sapiens (human) |
| ITGB3 | hsa:3690 | path:hsa05163 | Human cytomegalovirus infection - Homo sapiens (human) |
| ITGB3 | hsa:3690 | path:hsa05165 | Human papillomavirus infection - Homo sapiens (human) |
| ITGB3 | hsa:3690 | path:hsa05168 | Herpes simplex virus 1 infection - Homo sapiens (human) |
| ITGB3 | hsa:3690 | path:hsa05205 | Proteoglycans in cancer - Homo sapiens (human) |
| ITGB3 | hsa:3690 | path:hsa05206 | MicroRNAs in cancer - Homo sapiens (human) |
| ITGB3 | hsa:3690 | path:hsa05410 | Hypertrophic cardiomyopathy - Homo sapiens (human) |
| ITGB3 | hsa:3690 | path:hsa05412 | Arrhythmogenic right ventricular cardiomyopathy - Homo sapiens (human) |
| ITGB3 | hsa:3690 | path:hsa05414 | Dilated cardiomyopathy - Homo sapiens (human) |
| ITGB3 | hsa:3690 | path:hsa05418 | Fluid shear stress and atherosclerosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ITGAV | ITGB3 | 10022831 10545505 10837075 11146654 11335727 11532940 11553709 12000961 14697347 15031725 16919435 18353785 19161977 19339212 19449109 22035837 26192618 7512751 7529872 7657702 8636223 8755653 9295024 9763615 | interaction type | N/A | ACSN |
| ETS1 | ITGB3 | 10048576 15001984 15003528 15111329 15181457 16079281 16391805 16556862 16682805 17615296 17872466 18337545 19208835 19564415 20589835 21041997 21081489 21317430 22439866 22608498 23691193 24376839 26192618 7512751 7528107 8844971 9157999 9811054 | interaction type | N/A | ACSN |
| PTP4A3 | ITGB3 | 10048576 16617148 16831886 17563753 17671186 18832382 20731704 21317430 22406545 23691193 24376839 26192618 7512751 7528107 | interaction type | N/A | ACSN |
| ITGB3 | L1CAM | 11553709 19161977 26192618 8636223 9003039 | association | N/A | ACSN |
| CEACAM1 | ITGB3 | 11485912 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| DAB1 | ITGB3 | 20005715 | interaction type | N/A | PSP |
| DOK1 | ITGB3 | 12606711 18988627 20005715 | interaction type | N/A | PSP,SignaLink |
| EPS8 | ITGB3 | 20005715 | interaction type | N/A | PSP |
| FLNB | ITGB3 | 20005715 | interaction type | N/A | PSP |
| MAPK8IP1 | ITGB3 | 20005715 | interaction type | N/A | PSP,SignaLink |
| PXN | ITGB3 | 20005715 | interaction type | N/A | PSP |
| SHC1 | ITGB3 | 20005715 | interaction type | N/A | PSP |
| DAB1 | ITGB3 | 12606711 18988627 20005715 20005715 | N/A | N/A | SignaLink |
| SHC1 | ITGB3 | 20005715 20005715 | N/A | N/A | SignaLink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | ITGB3 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| GATA1 | ITGB3 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | ITGB3 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| HIF1A | ITGB3 | 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| YBX1 | ITGB3 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | ITGB3 | 11556732 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOSL1 | ITGB3 | 23319049 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HOXA10 | ITGB3 | 11875117 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HOXD3 | ITGB3 | 14610084 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| JUND | ITGB3 | 23319049 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SP1 | ITGB3 | 23319049 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| DAND5 | ITGB3 | 23319049 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MYB | ITGB3 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000029D9F1 | ITGB3 | 21282569 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000122ED0 | ITGB3 | 23622248 25416803 26445551 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,clash,miRNA interference luciferase reporter assay | TarBase |
| URS0000031E12 | ITGB3 | 23981581 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,immunocytochemistry,miRNA interference luciferase reporter assay | TarBase |
| URS00003CF1AD | ITGB3 | 24443232 25416803 25924850 | mrna cleavage,inhibition | experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS000075C1E1 | ITGB3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002A8BC6 | ITGB3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032AE90 | ITGB3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E5ECC | ITGB3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A760 | ITGB3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002152A8 | ITGB3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000137EDE | ITGB3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000019907A | ITGB3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C770D | ITGB3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FC26E | ITGB3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003758F0 | ITGB3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001F5B39 | ITGB3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C7B2B | ITGB3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EED18 | ITGB3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C5969 | ITGB3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002075FA | ITGB3 | 25416803 27499367 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS0000065D58 | ITGB3 | 25416803 27576787 | mrna cleavage,inhibition | western blot,miRNA interference luciferase reporter assay | TarBase |
| URS00000B59A2 | ITGB3 | 25416803 26506238 | mrna cleavage,inhibition | experimental interaction detection,western blot,miRNA interference luciferase reporter assay | TarBase |
| URS00000254A6 | ITGB3 | 25416803 27431198 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SRC | ITGB3 | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
| PDPK1 | ITGB3 | 22135298 | phosphorylation | N/A | PhosphoSite |
| AKT1 | ITGB3 | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
| VWF | ITGB3 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | VWF | 25361965 | interaction type | N/A | PTMCode2 |
| ITGAV | ITGB3 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | ITGAV | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | ITGA2B | 25361965 | interaction type | N/A | PTMCode2 |
| ITGA2B | ITGB3 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | KDR | 25361965 | interaction type | N/A | PTMCode2 |
| KDR | ITGB3 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | AKT1 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | THY1 | 25361965 | interaction type | N/A | PTMCode2 |
| THY1 | ITGB3 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | ITGA5 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGA5 | ITGB3 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | COL1A2 | 25361965 | interaction type | N/A | PTMCode2 |
| COL1A2 | ITGB3 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | ILK | 25361965 | interaction type | N/A | PTMCode2 |
| ILK | ITGB3 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | FGA | 25361965 | interaction type | N/A | PTMCode2 |
| FGA | ITGB3 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | CD36 | 25361965 | interaction type | N/A | PTMCode2 |
| CD36 | ITGB3 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | DAB2 | 25361965 | interaction type | N/A | PTMCode2 |
| DAB2 | ITGB3 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | TLN1 | 25361965 | interaction type | N/A | PTMCode2 |
| TLN1 | ITGB3 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | HBA1 | 25361965 | interaction type | N/A | PTMCode2 |
| HBA1 | ITGB3 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | PTK2B | 25361965 | interaction type | N/A | PTMCode2 |
| PTK2B | ITGB3 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | SRC | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | ANGPTL3 | 25361965 | interaction type | N/A | PTMCode2 |
| ANGPTL3 | ITGB3 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | PTPN1 | 25361965 | interaction type | N/A | PTMCode2 |
| PTPN1 | ITGB3 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | SHC1 | 25361965 | interaction type | N/A | PTMCode2 |
| SHC1 | ITGB3 | 25361965 | interaction type | N/A | PTMCode2 |
| THBS1 | ITGB3 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | THBS1 | 25361965 | interaction type | N/A | PTMCode2 |
| VTN | ITGB3 | 25361965 | interaction type | N/A | PTMCode2 |
| ITGB3 | VTN | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| COL1A2 | ITGB3 | 14525934 1693626 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| VIM | ITGB3 | 25348397 | N/A | physical interaction | ComPPI |
| DAB2 | ITGB3 | 12606711 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| SYK | ITGB3 | 25348397 | N/A | physical interaction | ComPPI |
| PTK2B | ITGB3 | 11683411 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| PECAM1 | ITGB3 | 25348397 | N/A | physical interaction,in vivo | ComPPI |
| CD36 | ITGB3 | 11238109 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| LYN | ITGB3 | 14593208 24234451 25348397 | physical association | enzyme linked immunosorbent assay | ComPPI,IntAct |
| PTPN11 | ITGB3 | 12791772 24234451 25348397 | association | coimmunoprecipitation | ComPPI,IntAct |
| SRC | ITGB3 | 11723131 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| DOK1 | ITGB3 | 12606711 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| KDR | ITGB3 | 10022831 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| SHC1 | ITGB3 | 10964917 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| MAPK3 | ITGB3 | 25348397 | N/A | physical interaction | ComPPI |
| ITGB1 | ITGB3 | 25348397 | N/A | physical interaction | ComPPI |
| TGM2 | ITGB3 | 10684262 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| FLNA | ITGB3 | 24234451 25348397 25849143 | physical association | nuclear magnetic resonance,surface plasmon resonance,physical interaction,surface plasmon resonance array | ComPPI,IntAct |
| ITGAV | ITGB3 | 11546839 11884718 14525934 15299032 16099422 1694173 20639902 22178926 24234451 24658351 25348397 9686320 | physical association | anti bait coimmunoprecipitation,experimental interaction detection,molecular sieving,pull down,x-ray crystallography,physical interaction,enzyme linked immunosorbent assay,in vitro,solid phase assay | ComPPI,HPRD,IntAct |
| CIB1 | ITGB3 | 25348397 | N/A | physical interaction | ComPPI |
| PDGFRB | ITGB3 | 10964931 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| PLA2G2A | ITGB3 | 25348397 | N/A | physical interaction | ComPPI |
| PDGFRA | ITGB3 | 11953315 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| DAB1 | ITGB3 | 12606711 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| THBS1 | ITGB3 | 14525934 2478219 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| VTN | ITGB3 | 14525934 16195248 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| ITGB3 | TLN1 | 10497223 11932255 12606711 14525934 16546176 24234451 25348397 | N/A | experimental interaction detection,physical interaction,affinity technology,enzyme linked immunosorbent assay,saturation binding,in vitro,in vivo | ComPPI,HPRD,IntAct |
| ITGB3 | P2RY2 | 25348397 | N/A | in vitro,in vivo | ComPPI |
| ITGB3 | EPS8 | 12606711 14525934 24234451 25348397 | N/A | experimental interaction detection,pull down,in vitro | ComPPI,HPRD,IntAct |
| ITGB3 | ILK | 12372433 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| ITGB3 | NUMB | 12606711 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| ITGB3 | PDPK1 | 10896934 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| ITGB3 | ITGA2B | 11606749 1429573 14525934 14681217 15067009 15379538 19279667 24234451 25348397 | physical association | coimmunoprecipitation,experimental interaction detection,nuclear magnetic resonance,pull down,x-ray crystallography,physical interaction,lex-a dimerization assay,in vitro,in vivo,tandem affinity purification,surface plasmon resonance array | ComPPI,HPRD,IntAct |
| ITGB3 | ITGB3BP | 11864709 14525934 25348397 7593198 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD |
| ITGB3 | ANGPTL3 | 11877390 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| ITGB3 | TNS2 | 12606711 14525934 24234451 25348397 | N/A | experimental interaction detection,pull down,in vitro | ComPPI,HPRD,IntAct |
| ITGB3 | CAPN1 | 14525934 25348397 7592818 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| ITGB3 | NID1 | 14525934 25348397 27898060 8831898 9686320 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| ITGB3 | FGA | 11460491 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| ITGB3 | FGG | 10747940 14525934 24234451 24789099 25348397 25398877 27898060 | physical association | experimental interaction detection,fluorescence-activated cell sorting,physical interaction,enzyme linked immunosorbent assay,in vitro | ComPPI,HPRD,IntAct,OmniPath |
| ITGB3 | ITGA5 | 25348397 | N/A | physical interaction,in vitro | ComPPI |
| ITGB3 | AKT1 | 10896934 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| ITGB3 | PTK2 | 25348397 | N/A | physical interaction | ComPPI |
| ITGB3 | FLNB | 25348397 | N/A | physical interaction | ComPPI |
| ITGB3 | PXN | 25348397 | N/A | physical interaction | ComPPI |
| ITGB3 | EPHA2 | 25348397 | N/A | physical interaction | ComPPI |
| ITGB3 | P4HB | 25348397 | N/A | physical interaction | ComPPI |
| ITGB3 | PLA2G4A | 25348397 | N/A | physical interaction | ComPPI |
| ITGB3 | PRKCB | 25348397 | N/A | physical interaction | ComPPI |
| ITGB3 | PAK4 | 25348397 | N/A | physical interaction | ComPPI |
| ITGB3 | MMP2 | 25348397 | N/A | physical interaction | ComPPI |
| ITGB3 | ITGA4 | 25348397 | N/A | physical interaction | ComPPI |
| ITGB3 | FERMT3 | 25348397 | N/A | physical interaction | ComPPI |
| ITGB3 | PDK1 | 25348397 | N/A | physical interaction | ComPPI |
| ITGB3 | CDK1 | 25348397 | N/A | physical interaction | ComPPI |
| ITGB3 | FN1 | 14525934 1694173 24234451 24658351 24789099 25348397 | physical association | experimental interaction detection,fluorescence-activated cell sorting,molecular sieving,x-ray crystallography,physical interaction,solid phase assay | ComPPI,HPRD,IntAct |
| ITGB3 | RABGAP1 | 12606711 24234451 25348397 | N/A | pull down | ComPPI,IntAct |
| ITGB3 | ANKS1B | 12606711 24234451 25348397 | N/A | pull down | ComPPI,IntAct |
| ITGB3 | GULP1 | 12606711 24234451 25348397 | N/A | pull down | ComPPI,IntAct |
| ITGB3 | RGS12 | 12606711 24234451 25348397 | N/A | pull down | ComPPI,IntAct |
| ITGB3 | MAPK8IP1 | 12606711 24234451 25348397 | N/A | pull down | ComPPI,IntAct |
| ITGB3 | PTPN1 | 16115959 24234451 25348397 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation | ComPPI,IntAct |
| ITGB3 | PTPRZ1 | 20639902 24234451 25348397 | colocalization,physical association | anti bait coimmunoprecipitation,confocal microscopy | ComPPI,IntAct |
| ITGB3 | ADAM15 | 24234451 24789099 25348397 | physical association | enzyme linked immunosorbent assay | ComPPI,IntAct |
| ITGB3 | CX3CL1 | 23125415 24234451 24789099 25348397 | association,physical association | anti bait coimmunoprecipitation,pull down,surface plasmon resonance,enzyme linked immunosorbent assay | ComPPI,IntAct |
| ITGB3 | CX3CR1 | 23125415 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| ITGB3 | ITGB3 | 11606749 12606711 14525934 14681217 22178926 24234451 | physical association | cosedimentation in solution,experimental interaction detection,pull down,lex-a dimerization assay,comigration in non denaturing gel electrophoresis | HPRD,IntAct |
| THY1 | ITGB3 | 14525934 15897908 | N/A | experimental interaction detection | HPRD |
| ITGB3 | FBLN2 | 10848816 14525934 | N/A | experimental interaction detection | HPRD |
| ITGB3 | LIN-10 | 12606711 24234451 | N/A | pull down | IntAct |
| ITGB3 | CEACAM1 | 11485912 27898060 | N/A | N/A | OmniPath |
| SRC | ITGB3 | 10330414 11723131 12359711 14996908 15695822 15699036 16935858 18088087 18156175 18364349 18398066 21956114 27898060 8631894 | inhibition,stimulant | N/A | OmniPath |
| CAPN1 | ITGB3 | 27898060 7592818 | inhibition | N/A | OmniPath |
| PDPK1 | ITGB3 | 10896934 18578522 27898060 | stimulant | N/A | OmniPath |
| AKT1 | ITGB3 | 10896934 18578522 27898060 | inhibition,stimulant | N/A | OmniPath |
| PDK1 | ITGB3 | 10896934 18578522 27898060 | N/A | N/A | OmniPath |
| ITGB3 | ITGA2B | 10358085 11606749 1429573 14681217 15067009 15379538 19279667 19805198 22178926 25849143 27898060 7531639 8663002 | N/A | N/A | OmniPath |
| ITGA5 | ITGB3 | 1694173 22470492 26344197 27898060 9516430 9914169 | N/A | N/A | OmniPath |
| SYK | ITGB3 | 27898060 8631894 | stimulant | N/A | OmniPath |
| PLAUR | ITGB3 | 27383564 27898060 | stimulant | N/A | OmniPath |
| ADAM15 | ITGB3 | 27898060 9516430 9914169 | stimulant | N/A | OmniPath |
| RGS6 | ITGB3 | 17609107 27898060 | inhibition | N/A | OmniPath |
| FBN1 | ITGB3 | 20686071 27898060 8617364 | N/A | N/A | OmniPath |
| MFGE8 | ITGB3 | 24441829 27898060 | N/A | N/A | OmniPath |