Gene Information gene info

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GENE：JUND

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol JUND
FullNmae JunD proto-oncogene, AP-1 transcription factor subunit
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6206
EnsembleID ENSG00000130522
Uniprot P17535

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
JUND autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
JUND GO:0000122,GO:0000785,GO:0000976,GO:0000978,GO:0000981,GO:0000981,GO:0001221,GO:0001228,GO:0002076,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005667,GO:0006357,GO:0006357,GO:0008134,GO:0010467,GO:0017053,GO:0019899,GO:0035976,GO:0042127,GO:0045669,GO:0045944,GO:0051726,GO:0071277,GO:0090575,GO:1990837

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
JUND hsa:3727 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
JUND hsa:3727 path:hsa04380 Osteoclast differentiation - Homo sapiens (human)
JUND hsa:3727 path:hsa04657 IL-17 signaling pathway - Homo sapiens (human)
JUND hsa:3727 path:hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
JUND HIF1A 20535745 26192618 interaction type N/A ACSN
JUND CXCL12 20535745 26192618 interaction type N/A ACSN
JUND CCND1 17146436 23180781 physical association anti tag coimmunoprecipitation InnateDB
NOS2 JUND 12788789 23180781 physical association electrophoretic mobility supershift assay InnateDB
JDP2 JUND 18671972 23180781 physical association anti tag coimmunoprecipitation InnateDB
JUND MMP9 18028425 23180781 physical association anti tag coimmunoprecipitation InnateDB
JUND IL11 23180781 9488674 physical association electrophoretic mobility supershift assay InnateDB
HOXC6 JUND 18655788 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL21 JUND 19617351 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL21R JUND 19617351 23180781 physical association anti tag coimmunoprecipitation InnateDB
ITGAX JUND 12576324 23180781 physical association electrophoretic mobility supershift assay InnateDB
ELF1 JUND 23180781 7648395 physical association anti tag coimmunoprecipitation InnateDB
JUND IL5 12354764 23180781 physical association electrophoretic mobility supershift assay InnateDB
JUND FOSL2 12354764 23180781 physical association electrophoretic mobility supershift assay InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 JUND 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 JUND 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 JUND 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 JUND 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA JUND 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF JUND 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 JUND 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 JUND 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 JUND 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 JUND 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 JUND 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS JUND 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A JUND 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A JUND 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF JUND 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 JUND 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 JUND 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MEN1 JUND 22327296 trascriptional regulation,stimulation inferred by curator TFlink
RBMX JUND 16707624 trascriptional regulation,stimulation inferred by curator TFlink
ZIC1 JUND 20713527 trascriptional regulation,stimulation inferred by curator TFlink
POU2F1 JUND N/A trascriptional regulation,stimulation inferred by curator TFlink
SP1 JUND N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004929F1 JUND 20622002 rna interference,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00004929F1 JUND 20371350 20622002 23592263 25416803 26701625 27184257 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS0000237AF9 JUND 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000021D7C8 JUND 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000015A0D9 JUND 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002373FD JUND 20371350 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003E226A JUND 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000017CCCB JUND 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000001A7A JUND 20371350 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000018D2BE JUND 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001123BD JUND 25416803 25788572 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr TarBase
URS00000D6C3F JUND 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002F72ED JUND 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000192A75 JUND 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000246356 JUND 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MAPK8 JUND 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
MAPK1 JUND 25361965 interaction type N/A PTMCode2
JUND MAPK1 25361965 interaction type N/A PTMCode2
BCL6 JUND 25361965 interaction type N/A PTMCode2
JUND BCL6 25361965 interaction type N/A PTMCode2
JUND FOSL2 25361965 interaction type N/A PTMCode2
FOSL2 JUND 25361965 interaction type N/A PTMCode2
JUND JDP2 25361965 interaction type N/A PTMCode2
JDP2 JUND 25361965 interaction type N/A PTMCode2
JUND FOS 25361965 interaction type N/A PTMCode2
FOS JUND 25361965 interaction type N/A PTMCode2
JUND MAPK8 25361965 interaction type N/A PTMCode2
JUND MEN1 25361965 interaction type N/A PTMCode2
MEN1 JUND 25361965 interaction type N/A PTMCode2
JUND SMAD4 25361965 interaction type N/A PTMCode2
SMAD4 JUND 25361965 interaction type N/A PTMCode2
JUND ATF3 25361965 interaction type N/A PTMCode2
ATF3 JUND 25361965 interaction type N/A PTMCode2
JUND MAPK10 25361965 interaction type N/A PTMCode2
MAPK10 JUND 25361965 interaction type N/A PTMCode2
FOSB JUND 25361965 interaction type N/A PTMCode2
JUND FOSB 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HBZ JUND 25348397 N/A physical interaction ComPPI
MAPK9 JUND 14525934 25348397 8945519 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
RALBP1 JUND 25348397 N/A physical interaction ComPPI
SMAD4 JUND 10220381 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
JUNB JUND 25348397 N/A physical interaction ComPPI
BATF JUND 14525934 20102225 24234451 25348397 8570175 N/A two hybrid,experimental interaction detection,peptide array,in vitro,two hybrid ComPPI,HPRD,IntAct
MAPK1 JUND 14525934 14676207 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PRKCQ JUND 25348397 N/A physical interaction ComPPI
TBP JUND 14525934 25348397 7848298 N/A experimental interaction detection,in vitro ComPPI,HPRD
MAPK8 JUND 12052834 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
NFATC1 JUND 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
MAPK3 JUND 14525934 14676207 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
JUN JUND 24234451 25348397 25609649 association anti bait coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
AR JUND 24234451 24647988 25348397 27898060 physical association proximity ligation assay,split luciferase complementation ComPPI,IntAct,OmniPath
FOSL2 JUND 10713367 12052862 14525934 20102225 24234451 25348397 26496610 association anti tag coimmunoprecipitation,experimental interaction detection,peptide array,physical interaction,in vitro ComPPI,HPRD,IntAct
SMARCD1 JUND 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EP300 JUND 25348397 N/A physical interaction ComPPI
SMAD3 JUND 10220381 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ATF3 JUND 14525934 20102225 24234451 25348397 27898060 8152431 N/A experimental interaction detection,peptide array,physical interaction,in vivo ComPPI,HPRD,IntAct,OmniPath
COPS5 JUND 14525934 25348397 8837781 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
COP1 JUND 12615916 14525934 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
CREB5 JUND 25348397 N/A physical interaction ComPPI
JDP2 JUND 14525934 18671972 24234451 25348397 9154808 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach ComPPI,HPRD,IntAct
JUND NFE2L2 14525934 25348397 9872330 N/A experimental interaction detection,in vivo ComPPI,HPRD
JUND BRCA1 12080089 14525934 25348397 N/A affinity chromatography technology,two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
JUND ESR1 11477071 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
JUND FOSB 10942775 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
JUND DDIT3 10523647 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
JUND MEN1 12226747 14525934 25348397 9989505 N/A anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,isothermal titration calorimetry,pull down,x-ray crystallography,physical interaction,in vitro,in vivo ComPPI,HPRD
JUND NFE2L1 14525934 25348397 9872330 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
JUND BCL6 25348397 N/A physical interaction ComPPI
JUND FOS 12193410 14525934 15867431 20102225 20195357 24029232 24234451 25348397 25609649 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,display technology,experimental interaction detection,peptide array,physical interaction,tandem affinity purification ComPPI,HPRD,IntAct
JUND YY1 25348397 N/A physical interaction ComPPI
JUND ELAVL1 25348397 N/A physical interaction ComPPI
JUND HINFP 25348397 N/A physical interaction ComPPI
JUND SIRT1 25348397 N/A physical interaction ComPPI
JUND MDM2 20195357 24234451 25348397 physical association display technology,physical interaction,tandem affinity purification ComPPI,IntAct
JUND ACTR3 20195357 24234451 25348397 physical association display technology,physical interaction,tandem affinity purification ComPPI,IntAct
JUND SLC25A12 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
JUND PPARG 25348397 N/A physical interaction ComPPI
JUND TPM1 25348397 N/A physical interaction ComPPI
JUND EGR1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JUND CREB1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
JUND MEF2A 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
JUND NFATC2 25348397 N/A physical interaction ComPPI
JUND ARIH1 25348397 N/A physical interaction ComPPI
JUND MLLT6 25348397 N/A physical interaction ComPPI
JUND ARHGAP22 25348397 N/A physical interaction ComPPI
JUND MAPK10 22327296 24234451 25348397 phosphorylation reaction pull down,phosphorylation reaction,physical interaction,protein kinase assay ComPPI,IntAct
JUND TEAD1 24234451 25348397 26258633 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JUND FOSL1 24029232 24234451 25348397 26258633 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
JUND ETS1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
JUND ATF7 20102225 24234451 25348397 N/A peptide array ComPPI,IntAct
SOX2 JUND 25348397 N/A physical interaction ComPPI
SEPTIN2 JUND 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
ATF2 JUND 20102225 24234451 25348397 N/A peptide array,physical interaction ComPPI,IntAct
BATF3 JUND 20102225 24234451 25348397 physical association peptide array,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BLVRA JUND 15870194 27898060 stimulant N/A OmniPath
HOXC6 JUND 18655788 27898060 N/A N/A OmniPath
MEN1 JUND 10500243 12226747 12509449 16651450 16997566 22327296 27898060 9989505 inhibition,stimulant N/A OmniPath
MAPK3 JUND 14676207 22327296 27898060 stimulant N/A OmniPath
DDIT3 JUND 10523647 11426938 27898060 stimulant N/A OmniPath
JUND NFE2L2 16545679 27898060 9872330 N/A N/A OmniPath
MAPK1 JUND 14676207 22327296 27898060 stimulant N/A OmniPath
PAK1 JUND 16007120 27898060 N/A N/A OmniPath
JUND NRF1 27898060 9872330 N/A N/A OmniPath
MAPK8 JUND 12052834 14676207 16007120 16264271 17001009 22327296 27898060 stimulant N/A OmniPath
JDP2 JUND 18671972 27898060 9154808 N/A N/A OmniPath
JUND FOSL2 10713367 12052862 12354764 20102225 26186194 26496610 27898060 N/A N/A OmniPath
ELF1 JUND 27898060 7648395 N/A N/A OmniPath

Visualization










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