Gene Information gene info

GENE:KDM5B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KDM5B
FullNmae lysine demethylase 5B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18039
EnsembleID ENSG00000117139
Uniprot Q9UGL1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KDM5B mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
KDM5B autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KDM5B GO:0000785,GO:0003676,GO:0003676,GO:0003677,GO:0003714,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0006338,GO:0006355,GO:0007338,GO:0008270,GO:0008270,GO:0009791,GO:0010628,GO:0032452,GO:0032453,GO:0032453,GO:0033601,GO:0034647,GO:0034647,GO:0034647,GO:0042393,GO:0044344,GO:0045892,GO:0048511,GO:0060444,GO:0060763,GO:0060992,GO:0061038,GO:0070306,GO:1990830,GO:1990837,GO:2000864

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
KDM5B EZH2 23180781 24619877 physical association anti tag coimmunoprecipitation InnateDB
KDM5B SUZ12 23180781 24619877 physical association anti tag coimmunoprecipitation InnateDB
EED KDM5B 23180781 24619877 physical association anti tag coimmunoprecipitation InnateDB
KDM5B HOXA5 23180781 24619877 physical association anti tag coimmunoprecipitation InnateDB
KDM5B MYT1 23180781 24619877 physical association anti tag coimmunoprecipitation InnateDB
KDM5B RARB 23180781 24619877 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR KDM5B 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 KDM5B 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 KDM5B 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 KDM5B 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 KDM5B 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 KDM5B 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A KDM5B 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
FOXA1 KDM5B 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 KDM5B 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 KDM5B 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 KDM5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA KDM5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF KDM5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 KDM5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 KDM5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS KDM5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A KDM5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF KDM5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR KDM5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PAX9 KDM5B N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 KDM5B 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000272A3D KDM5B 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00001C3AC1 KDM5B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000237CBD KDM5B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005A8ED KDM5B 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001B9F58 KDM5B 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD231 KDM5B 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00007455B8 KDM5B 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 KDM5B 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA KDM5B 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C KDM5B 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002F3336 KDM5B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC KDM5B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 KDM5B 25416803 28082020 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00001E3523 KDM5B 25416803 26461474 26621457 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000076995 KDM5B 25416803 26131109 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
FAM90A1 KDM5B 25348397 N/A physical interaction ComPPI
HOXA1 KDM5B 25348397 N/A physical interaction ComPPI
MEOX2 KDM5B 25348397 N/A physical interaction ComPPI
GTF2A1 KDM5B 25348397 N/A physical interaction ComPPI
FOXC2 KDM5B 25348397 N/A physical interaction ComPPI
FOXG1 KDM5B 12657635 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
KDM5B RB1 14525934 15803180 16645588 21980403 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
KDM5B PAX9 12657635 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
KDM5B PRPF4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KDM5B CACNA1H 25348397 N/A physical interaction ComPPI
KDM5B CDC20 25348397 N/A physical interaction ComPPI
KDM5B PCNX1 25348397 N/A physical interaction ComPPI
KDM5B SMARCC2 25348397 N/A physical interaction ComPPI
KDM5B DGKQ 25348397 N/A physical interaction ComPPI
KDM5B CACNA1A 25348397 N/A physical interaction ComPPI
KDM5B NR4A3 25348397 N/A physical interaction ComPPI
KDM5B BMP2K 25348397 N/A physical interaction ComPPI
KDM5B VGLL3 25348397 N/A physical interaction ComPPI
KDM5B CDX2 19336002 23202735 25348397 27898060 N/A physical interaction ComPPI,OmniPath
KDM5B CBX4 25348397 N/A physical interaction ComPPI
KDM5B SLITRK3 25348397 N/A physical interaction ComPPI
KDM5B AXIN2 25348397 N/A physical interaction ComPPI
KDM5B ONECUT2 25348397 N/A physical interaction ComPPI
KDM5B MAF 25348397 N/A physical interaction ComPPI
KDM5B ELF4 25348397 N/A physical interaction ComPPI
KDM5B SLC39A6 25348397 N/A physical interaction ComPPI
KDM5B BRD4 25348397 N/A physical interaction ComPPI
KDM5B RNF43 25348397 N/A physical interaction ComPPI
KDM5B RBM15B 25348397 N/A physical interaction ComPPI
KDM5B PRDM13 25348397 N/A physical interaction ComPPI
KDM5B DBNL 25348397 N/A physical interaction ComPPI
KDM5B RHOBTB2 25348397 N/A physical interaction ComPPI
KDM5B TAF2 25348397 N/A physical interaction ComPPI
KDM5B SHOX2 25348397 N/A physical interaction ComPPI
KDM5B ARID1B 25348397 N/A physical interaction ComPPI
KDM5B GRIN2B 25348397 N/A physical interaction ComPPI
KDM5B ZNF217 25348397 N/A physical interaction ComPPI
KDM5B RCOR1 25348397 N/A physical interaction ComPPI
KDM5B AR 25348397 N/A physical interaction ComPPI
KDM5B LMO2 25348397 N/A physical interaction ComPPI
KDM5B KLF10 20863814 25348397 27898060 N/A physical interaction ComPPI,OmniPath
KDM5B HDAC1 25348397 N/A physical interaction ComPPI
KDM5B CHD3 25348397 N/A physical interaction ComPPI
KDM5B KDM1A 25348397 N/A physical interaction ComPPI
KDM5B MTA2 25348397 N/A physical interaction ComPPI
KDM5B MTA3 25348397 N/A physical interaction ComPPI
KDM5B HDAC2 25348397 N/A physical interaction ComPPI
KDM5B RBBP7 25348397 N/A physical interaction ComPPI
KDM5B RBBP4 25348397 N/A physical interaction ComPPI
KDM5B MBD2 25348397 N/A physical interaction ComPPI
KDM5B MBD3 25348397 N/A physical interaction ComPPI
KDM5B HDAC4 25348397 N/A physical interaction ComPPI
KDM5B HDAC5 25348397 N/A physical interaction ComPPI
KDM5B HDAC7 25348397 N/A physical interaction ComPPI
KDM5B NCOR1 25348397 N/A physical interaction ComPPI
KDM5B ELAVL1 25348397 N/A physical interaction ComPPI
KDM5B TFAP2C 25348397 N/A physical interaction ComPPI
KDM5B MYC 25348397 N/A physical interaction ComPPI
KDM5B FBXW11 25348397 N/A physical interaction ComPPI
KDM5B TSPYL6 25348397 N/A physical interaction ComPPI
KDM5B TRIM25 25348397 N/A physical interaction ComPPI
KDM5B PPP1CA 19389623 24234451 25348397 N/A pull down ComPPI,IntAct
KDM5B CTCF 24234451 24937458 25348397 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct,OmniPath
H3C1 KDM5B 20228790 24234451 25348397 demethylation reaction demethylase assay ComPPI,IntAct
FST KDM5B 24234451 24937458 association chromatin immunoprecipitation assay IntAct
CAV1 KDM5B 24234451 24937458 association chromatin immunoprecipitation assay IntAct
CDC14A KDM5B 24234451 24937458 association chromatin immunoprecipitation assay IntAct
KDM5B WNT3A 24234451 24937458 association chromatin immunoprecipitation assay IntAct
TGFB2 KDM5B 24234451 24937458 association chromatin immunoprecipitation assay IntAct
KDM5B CLDN1 24234451 24937458 association chromatin immunoprecipitation assay IntAct
KDM5B CHST3 24234451 24937458 association chromatin immunoprecipitation assay IntAct
KDM5B PALD1 24234451 24937458 association chromatin immunoprecipitation assay IntAct
KDM5B ESRP1 24234451 24937458 association chromatin immunoprecipitation assay IntAct
SPDEF KDM5B 24234451 24937458 association chromatin immunoprecipitation assay IntAct
KDM5B ELF3 24234451 24937458 association chromatin immunoprecipitation assay IntAct
KDM5B CALML5 24234451 24937458 association chromatin immunoprecipitation assay IntAct
PTGIS KDM5B 24234451 24937458 association chromatin immunoprecipitation assay IntAct
ABCA4 KDM5B 24234451 24937458 association chromatin immunoprecipitation assay IntAct
KDM5B DNAJB12 24234451 24937458 association chromatin immunoprecipitation assay IntAct
ACTBL2 KDM5B 24234451 24937458 association chromatin immunoprecipitation assay IntAct
KDM5B H3C1 17909537 27898060 inhibition N/A OmniPath
KDM5B FOXG1 12657635 17973255 27898060 stimulant N/A OmniPath
PARP1 KDM5B 20832725 27898060 inhibition N/A OmniPath
KDM5B CBX4 19336002 23970103 27898060 stimulant N/A OmniPath
KDM5B PAX9 12657635 17373667 17973255 27898060 stimulant N/A OmniPath

Visualization