GENE:KDM5B
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | KDM5B |
FullNmae | lysine demethylase 5B |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:18039 |
EnsembleID | ENSG00000117139 |
Uniprot | Q9UGL1 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
KDM5B | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
KDM5B | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
KDM5B | GO:0000785,GO:0003676,GO:0003676,GO:0003677,GO:0003714,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0006338,GO:0006355,GO:0007338,GO:0008270,GO:0008270,GO:0009791,GO:0010628,GO:0032452,GO:0032453,GO:0032453,GO:0033601,GO:0034647,GO:0034647,GO:0034647,GO:0042393,GO:0044344,GO:0045892,GO:0048511,GO:0060444,GO:0060763,GO:0060992,GO:0061038,GO:0070306,GO:1990830,GO:1990837,GO:2000864 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
KDM5B | EZH2 | 23180781 24619877 | physical association | anti tag coimmunoprecipitation | InnateDB |
KDM5B | SUZ12 | 23180781 24619877 | physical association | anti tag coimmunoprecipitation | InnateDB |
EED | KDM5B | 23180781 24619877 | physical association | anti tag coimmunoprecipitation | InnateDB |
KDM5B | HOXA5 | 23180781 24619877 | physical association | anti tag coimmunoprecipitation | InnateDB |
KDM5B | MYT1 | 23180781 24619877 | physical association | anti tag coimmunoprecipitation | InnateDB |
KDM5B | RARB | 23180781 24619877 | physical association | anti tag coimmunoprecipitation | InnateDB |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | KDM5B | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
ESR1 | KDM5B | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
ETS1 | KDM5B | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA1 | KDM5B | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA2 | KDM5B | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA3 | KDM5B | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
HIF1A | KDM5B | 18971253 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
FOXA1 | KDM5B | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
YBX1 | KDM5B | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
FOXP3 | KDM5B | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
SMARCA4 | KDM5B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | KDM5B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | KDM5B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | KDM5B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | KDM5B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | KDM5B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | KDM5B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | KDM5B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
VDR | KDM5B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
PAX9 | KDM5B | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000237AF9 | KDM5B | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS0000272A3D | KDM5B | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
URS00001C3AC1 | KDM5B | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS0000237CBD | KDM5B | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000005A8ED | KDM5B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001B9F58 | KDM5B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003AD231 | KDM5B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00007455B8 | KDM5B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000049FAE8 | KDM5B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000025EABA | KDM5B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000012930C | KDM5B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002F3336 | KDM5B | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001012BC | KDM5B | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000F0F49 | KDM5B | 25416803 28082020 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
URS00001E3523 | KDM5B | 25416803 26461474 26621457 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
URS0000076995 | KDM5B | 25416803 26131109 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
FAM90A1 | KDM5B | 25348397 | N/A | physical interaction | ComPPI |
HOXA1 | KDM5B | 25348397 | N/A | physical interaction | ComPPI |
MEOX2 | KDM5B | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | KDM5B | 25348397 | N/A | physical interaction | ComPPI |
FOXC2 | KDM5B | 25348397 | N/A | physical interaction | ComPPI |
FOXG1 | KDM5B | 12657635 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD |
KDM5B | RB1 | 14525934 15803180 16645588 21980403 25348397 27898060 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD,OmniPath |
KDM5B | PAX9 | 12657635 14525934 25348397 | N/A | experimental interaction detection,physical interaction,two hybrid | ComPPI,HPRD |
KDM5B | PRPF4 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
KDM5B | CACNA1H | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | CDC20 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | PCNX1 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | SMARCC2 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | DGKQ | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | CACNA1A | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | NR4A3 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | BMP2K | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | VGLL3 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | CDX2 | 19336002 23202735 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
KDM5B | CBX4 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | SLITRK3 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | AXIN2 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | ONECUT2 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | MAF | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | ELF4 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | SLC39A6 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | BRD4 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | RNF43 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | RBM15B | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | PRDM13 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | DBNL | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | RHOBTB2 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | TAF2 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | SHOX2 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | ARID1B | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | GRIN2B | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | ZNF217 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | RCOR1 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | AR | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | LMO2 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | KLF10 | 20863814 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
KDM5B | HDAC1 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | CHD3 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | KDM1A | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | MTA2 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | MTA3 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | HDAC2 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | RBBP7 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | RBBP4 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | MBD2 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | MBD3 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | HDAC4 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | HDAC5 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | HDAC7 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | NCOR1 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | ELAVL1 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | TFAP2C | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | MYC | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | FBXW11 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | TSPYL6 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | TRIM25 | 25348397 | N/A | physical interaction | ComPPI |
KDM5B | PPP1CA | 19389623 24234451 25348397 | N/A | pull down | ComPPI,IntAct |
KDM5B | CTCF | 24234451 24937458 25348397 27898060 | physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation | ComPPI,IntAct,OmniPath |
H3C1 | KDM5B | 20228790 24234451 25348397 | demethylation reaction | demethylase assay | ComPPI,IntAct |
FST | KDM5B | 24234451 24937458 | association | chromatin immunoprecipitation assay | IntAct |
CAV1 | KDM5B | 24234451 24937458 | association | chromatin immunoprecipitation assay | IntAct |
CDC14A | KDM5B | 24234451 24937458 | association | chromatin immunoprecipitation assay | IntAct |
KDM5B | WNT3A | 24234451 24937458 | association | chromatin immunoprecipitation assay | IntAct |
TGFB2 | KDM5B | 24234451 24937458 | association | chromatin immunoprecipitation assay | IntAct |
KDM5B | CLDN1 | 24234451 24937458 | association | chromatin immunoprecipitation assay | IntAct |
KDM5B | CHST3 | 24234451 24937458 | association | chromatin immunoprecipitation assay | IntAct |
KDM5B | PALD1 | 24234451 24937458 | association | chromatin immunoprecipitation assay | IntAct |
KDM5B | ESRP1 | 24234451 24937458 | association | chromatin immunoprecipitation assay | IntAct |
SPDEF | KDM5B | 24234451 24937458 | association | chromatin immunoprecipitation assay | IntAct |
KDM5B | ELF3 | 24234451 24937458 | association | chromatin immunoprecipitation assay | IntAct |
KDM5B | CALML5 | 24234451 24937458 | association | chromatin immunoprecipitation assay | IntAct |
PTGIS | KDM5B | 24234451 24937458 | association | chromatin immunoprecipitation assay | IntAct |
ABCA4 | KDM5B | 24234451 24937458 | association | chromatin immunoprecipitation assay | IntAct |
KDM5B | DNAJB12 | 24234451 24937458 | association | chromatin immunoprecipitation assay | IntAct |
ACTBL2 | KDM5B | 24234451 24937458 | association | chromatin immunoprecipitation assay | IntAct |
KDM5B | H3C1 | 17909537 27898060 | inhibition | N/A | OmniPath |
KDM5B | FOXG1 | 12657635 17973255 27898060 | stimulant | N/A | OmniPath |
PARP1 | KDM5B | 20832725 27898060 | inhibition | N/A | OmniPath |
KDM5B | CBX4 | 19336002 23970103 27898060 | stimulant | N/A | OmniPath |
KDM5B | PAX9 | 12657635 17373667 17973255 27898060 | stimulant | N/A | OmniPath |