Gene Information gene info

GENE:MARCKSL1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MARCKSL1
FullNmae MARCKS like 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7142
EnsembleID ENSG00000175130
Uniprot P49006

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MARCKSL1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MARCKSL1 GO:0005515,GO:0005516,GO:0005737,GO:0005856,GO:0005886,GO:0005886,GO:0007015,GO:0007417,GO:0008283,GO:0008284,GO:0051015,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MARCKSL1 hsa:65108 path:hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human)
MARCKSL1 hsa:65108 path:hsa05140 Leishmaniasis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TLR2 MARCKSL1 21827211 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 MARCKSL1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 MARCKSL1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 MARCKSL1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 MARCKSL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MARCKSL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MARCKSL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MARCKSL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MARCKSL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MARCKSL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MARCKSL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 MARCKSL1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000019D79B MARCKSL1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000137EDE MARCKSL1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 MARCKSL1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC MARCKSL1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002F0130 MARCKSL1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5ECC MARCKSL1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000014F13C MARCKSL1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000279B6F MARCKSL1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 MARCKSL1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F MARCKSL1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 MARCKSL1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 MARCKSL1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA MARCKSL1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002394F5 MARCKSL1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E MARCKSL1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 MARCKSL1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004DEA91 MARCKSL1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005FDCD1 MARCKSL1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 MARCKSL1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D MARCKSL1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 MARCKSL1 25416803 27502506 mrna cleavage,inhibition array technology,nucleotide sequence identification,western blot,miRNA interference luciferase reporter assay TarBase
URS0000324096 MARCKSL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000031E12 MARCKSL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000A07C1 MARCKSL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000000B1C9 MARCKSL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000029979D MARCKSL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000237CBD MARCKSL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000002103A MARCKSL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002A79D1 MARCKSL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000017CCCB MARCKSL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000116F83 MARCKSL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000032EF64 MARCKSL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000247AC6 MARCKSL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000047A8F MARCKSL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001919B0 MARCKSL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000214763 MARCKSL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002E728C MARCKSL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000122ED0 MARCKSL1 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ATR MARCKSL1 22135298 phosphorylation N/A PhosphoSite
MARCKSL1 DCTN2 25361965 interaction type N/A PTMCode2
DCTN2 MARCKSL1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ATP6V1D MARCKSL1 25348397 N/A physical interaction ComPPI
ZBTB43 MARCKSL1 25348397 N/A physical interaction ComPPI
MRM3 MARCKSL1 25348397 N/A physical interaction ComPPI
KBTBD7 MARCKSL1 25348397 N/A physical interaction ComPPI
MAPK14 MARCKSL1 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NTRK1 MARCKSL1 25348397 N/A physical interaction ComPPI
PTPN1 MARCKSL1 25348397 N/A physical interaction ComPPI
RBP4 MARCKSL1 25348397 N/A physical interaction ComPPI
RALA MARCKSL1 25348397 N/A physical interaction ComPPI
CFTR MARCKSL1 25348397 N/A physical interaction ComPPI
EWSR1 MARCKSL1 25348397 N/A physical interaction ComPPI
RALB MARCKSL1 25348397 N/A physical interaction ComPPI
BCCIP MARCKSL1 25348397 N/A physical interaction ComPPI
CDK2 MARCKSL1 25348397 N/A physical interaction ComPPI
PRKN MARCKSL1 25348397 N/A physical interaction ComPPI
PAX6 MARCKSL1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELAVL1 MARCKSL1 25348397 N/A physical interaction ComPPI
TOP3A MARCKSL1 25348397 N/A physical interaction ComPPI
BRCA1 MARCKSL1 25348397 N/A physical interaction ComPPI
PPP4R2 MARCKSL1 25348397 N/A physical interaction ComPPI
SOD1 MARCKSL1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
TGOLN2 MARCKSL1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ATP6V1A MARCKSL1 25348397 N/A physical interaction ComPPI
DCTN2 MARCKSL1 10827182 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
MARCKSL1 LOXL2 24234451 24863880 25348397 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid ComPPI,IntAct,OmniPath
MARCKSL1 MRPL16 25348397 N/A physical interaction ComPPI
MARCKSL1 ATP6V0A1 25348397 N/A physical interaction ComPPI
MARCKSL1 NDUFB5 25348397 N/A physical interaction ComPPI
MARCKSL1 MRPL46 25348397 N/A physical interaction ComPPI
MARCKSL1 MRPL30 25348397 N/A physical interaction ComPPI
MARCKSL1 PCDH7 25348397 N/A physical interaction ComPPI
MARCKSL1 MRPL45 25348397 N/A physical interaction ComPPI
MARCKSL1 MRPL22 25348397 N/A physical interaction ComPPI
MARCKSL1 PAN2 25348397 N/A physical interaction ComPPI
MARCKSL1 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MARCKSL1 TMEM216 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MARCKSL1 SNX21 25348397 N/A physical interaction ComPPI
MARCKSL1 NMT2 25348397 N/A physical interaction ComPPI
MARCKSL1 RMI1 25348397 N/A physical interaction ComPPI
MARCKSL1 NMT1 25348397 N/A physical interaction ComPPI
MARCKSL1 PPP4R3A 25348397 N/A physical interaction ComPPI
MARCKSL1 SCRN2 25348397 N/A physical interaction ComPPI
MARCKSL1 ATP11C 25348397 N/A physical interaction ComPPI
MARCKSL1 ATP6V0A2 25348397 N/A physical interaction ComPPI
MARCKSL1 SOAT1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
MARCKSL1 OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
MARCKSL1 BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
MARCKSL1 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
MARCKSL1 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct

Visualization