Gene Information gene info

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GENE：MARK3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MARK3
FullNmae microtubule affinity regulating kinase 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6897
EnsembleID ENSG00000075413
Uniprot P27448

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MARK3 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MARK3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MARK3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MARK3 GO:0004674,GO:0004674,GO:0004674,GO:0005515,GO:0005524,GO:0005737,GO:0005737,GO:0005737,GO:0005829,GO:0005886,GO:0005886,GO:0006468,GO:0018105,GO:0030425,GO:0032092,GO:0035331,GO:0035556,GO:0036289,GO:0048156,GO:0050321,GO:0050321,GO:0070062,GO:0106310,GO:1900181

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 MARK3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 MARK3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 MARK3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 MARK3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP63 MARK3 17521434 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 MARK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MARK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MARK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MARK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MARK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MARK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MARK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MARK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MARK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 MARK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001597DC MARK3 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PRKACA MARK3 22135298 phosphorylation N/A PhosphoSite
PRKCI MARK3 22135298 phosphorylation N/A PhosphoSite
STK11 MARK3 22135298 phosphorylation N/A PhosphoSite
MARK3 FEZ1 22135298 phosphorylation N/A PhosphoSite
MARK3 PPP1R2 22135298 phosphorylation N/A PhosphoSite
MARK3 CDC25C 22135298 phosphorylation N/A PhosphoSite
PRKCZ MARK3 22135298 phosphorylation N/A PhosphoSite
HDAC7 MARK3 25361965 interaction type N/A PTMCode2
MARK3 HDAC7 25361965 interaction type N/A PTMCode2
PRKCQ MARK3 25361965 interaction type N/A PTMCode2
MARK3 PRKCQ 25361965 interaction type N/A PTMCode2
YWHAB MARK3 25361965 interaction type N/A PTMCode2
MARK3 YWHAB 25361965 interaction type N/A PTMCode2
YWHAH MARK3 25361965 interaction type N/A PTMCode2
MARK3 YWHAH 25361965 interaction type N/A PTMCode2
KSR1 MARK3 25361965 interaction type N/A PTMCode2
MARK3 KSR1 25361965 interaction type N/A PTMCode2
MARK2 MARK3 25361965 interaction type N/A PTMCode2
MARK3 MARK2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
DYNLL1 MARK3 25348397 N/A in vitro ComPPI
TTR MARK3 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
VPS11 MARK3 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
YWHAG MARK3 15324660 16959763 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,physical interaction,in vivo ComPPI,IntAct
ATP6V0C MARK3 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PRKCQ MARK3 17363905 24234451 25348397 physical association anti bait coimmunoprecipitation,in vitro,in vivo ComPPI,IntAct
PIM1 MARK3 25348397 N/A physical interaction ComPPI
CTBP2 MARK3 25348397 N/A physical interaction ComPPI
HDAC4 MARK3 25348397 N/A physical interaction ComPPI
YWHAB MARK3 15324660 16959763 17353931 24234451 24255178 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,physical interaction ComPPI,IntAct
YWHAZ MARK3 14676191 15161933 16306228 16959763 24234451 25348397 25852190 association,physical association anti tag coimmunoprecipitation,far western blotting,pull down,physical interaction,in vitro,tandem affinity purification ComPPI,IntAct
PRKAA1 MARK3 25348397 N/A physical interaction ComPPI
UBB MARK3 25348397 N/A nuclear magnetic resonance,pull down,physical interaction ComPPI
UBC MARK3 25348397 N/A nuclear magnetic resonance,pull down,physical interaction ComPPI
RPS27A MARK3 25348397 N/A nuclear magnetic resonance,pull down,physical interaction ComPPI
UBA52 MARK3 25348397 N/A nuclear magnetic resonance,pull down,physical interaction ComPPI
NTRK1 MARK3 25348397 N/A physical interaction ComPPI
CDH1 MARK3 25348397 N/A physical interaction ComPPI
PKP2 MARK3 12941695 24234451 25348397 association,physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,IntAct
IKBKB MARK3 17363905 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HEY1 MARK3 25348397 N/A physical interaction ComPPI
MAP2 MARK3 25348397 N/A physical interaction ComPPI
MAPT MARK3 23666762 24234451 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
PPP2CB MARK3 25348397 N/A physical interaction ComPPI
CAPZA1 MARK3 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HNRNPL MARK3 25348397 N/A physical interaction ComPPI
YWHAQ MARK3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PNPLA2 MARK3 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
YWHAH MARK3 14676191 16959763 17979178 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
SFN MARK3 15778465 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,tandem affinity purification ComPPI,IntAct
YWHAE MARK3 16306228 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MARK2 MARK3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CASQ2 MARK3 25348397 N/A physical interaction ComPPI
FANCF MARK3 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
HDAC5 MARK3 25348397 N/A physical interaction ComPPI
PPM1B MARK3 12556533 24234451 25348397 physical association phosphatase assay ComPPI,IntAct
HDAC7 MARK3 25348397 N/A physical interaction ComPPI
MARK3 CPSF4 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
MARK3 PMPCB 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
MARK3 ASB13 16169070 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
MARK3 NOL11 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
MARK3 ANKRD7 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
MARK3 SAAL1 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
MARK3 CHGB 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
MARK3 KSR1 25348397 N/A physical interaction,in vivo ComPPI
MARK3 CDC25C 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
MARK3 RASGRF1 25348397 N/A physical interaction ComPPI
MARK3 TCEA2 16169070 24234451 25348397 physical association pull down,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
MARK3 USP21 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MARK3 TADA2A 25348397 N/A physical interaction ComPPI
MARK3 TERF2 25348397 N/A physical interaction ComPPI
MARK3 MITF 25348397 N/A physical interaction ComPPI
MARK3 CAPZB 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MARK3 CNBP 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MARK3 DLG5 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MARK3 HNRNPDL 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MARK3 MTCL1 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MARK3 ALYREF 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MARK3 CEP192 25348397 N/A physical interaction ComPPI
MARK3 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MARK3 CPSF3 25348397 N/A physical interaction ComPPI
MARK3 MEX3C 25348397 N/A physical interaction ComPPI
MARK3 CERT1 25348397 N/A physical interaction ComPPI
MARK3 NRROS 25348397 N/A physical interaction ComPPI
MARK3 TMCC2 25348397 N/A physical interaction ComPPI
MARK3 NUAK2 25348397 N/A physical interaction ComPPI
MARK3 PCDHGB4 25348397 N/A physical interaction ComPPI
MARK3 CDH19 25348397 N/A physical interaction ComPPI
MARK3 MANSC1 25348397 N/A physical interaction ComPPI
MARK3 TRIM25 25348397 N/A physical interaction ComPPI
MARK3 FOS 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MARK3 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
STK11 MARK3 12879020 14976552 17192257 19369195 27898060 stimulant N/A OmniPath
PIM1 MARK3 15319445 26186194 27898060 inhibition N/A OmniPath
MARK3 CDC25C 10557092 10681541 10744722 10770932 10786669 11333986 11551930 12049736 12766774 12941695 14681223 14987992 15073169 15282313 15296723 15319445 15471901 15735676 15870257 15940258 15975956 16205633 16632641 16705183 16794575 16968750 17172433 17237275 17242184 17409144 17976513 18071308 18510930 19933706 20068231 20530684 20637859 20639859 23993743 25299772 25633196 25809478 25940704 27898060 7982962 9278511 9278512 9543386 9836640 N/A N/A OmniPath
PRKCZ MARK3 15084291 27898060 inhibition N/A OmniPath
MARK3 PPP1R2 25028520 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B7081 MARK3 27087310 direct interaction,inhibition N/A NPInter

Visualization










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