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GENE：MLXIP

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MLXIP
FullNmae MLX interacting protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17055
EnsembleID ENSG00000175727
Uniprot Q9HAP2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MLXIP autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MLXIP GO:0000785,GO:0000977,GO:0000978,GO:0000981,GO:0000981,GO:0001228,GO:0005634,GO:0005741,GO:0006357,GO:0045944,GO:0045944,GO:0046983

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MLXIP hsa:22877 path:hsa04931 Insulin resistance - Homo sapiens (human)
MLXIP hsa:22877 path:hsa04932 Non-alcoholic fatty liver disease - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MLX MLXIP 11557773 11744734 14672622 15199147 16782875 17143338 18458340 26192618 8955077 9192621 association N/A ACSN
MLXIP HK2 11557773 11744734 14672622 15199147 16782875 17143338 18458340 26192618 8955077 9192621 interaction type N/A ACSN
MLXIP PFKFB3 11557773 11744734 14672622 15199147 16782875 17143338 18458340 26192618 8955077 9192621 interaction type N/A ACSN
MLXIP LDHA 11557773 11744734 14672622 15199147 16782875 17143338 18458340 26192618 8955077 9192621 interaction type N/A ACSN
MLXIP TKT 11557773 11744734 14672622 15199147 16782875 17143338 18458340 26192618 8955077 9192621 interaction type N/A ACSN

Source Target Pmid Interactiontype Methods Database
GATA1 MLXIP 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 MLXIP 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 MLXIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MLXIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MLXIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MLXIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MLXIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MLXIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MLXIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MLXIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A MLXIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MLXIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 MLXIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MLXIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 MLXIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 MLXIP 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000122ED0 MLXIP 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 MLXIP 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000070B1D MLXIP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004505E4 MLXIP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F MLXIP 22473208 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS00000600E6 MLXIP 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000011A030 MLXIP 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000023F008 MLXIP 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001C770D MLXIP 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000017CCCB MLXIP 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002EF20A MLXIP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 MLXIP 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005F1B8C MLXIP 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000383DF4 MLXIP 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002578DA MLXIP 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000041FA2C MLXIP 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000085F64 MLXIP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 MLXIP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B MLXIP 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000046CDA6 MLXIP 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003D4175 MLXIP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003575B MLXIP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 MLXIP 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000029D793 MLXIP 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 MLXIP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E MLXIP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000148B91 MLXIP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 MLXIP 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F MLXIP 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 MLXIP 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 MLXIP 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 MLXIP 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 MLXIP 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 MLXIP 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA MLXIP 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D MLXIP 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 MLXIP 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C MLXIP 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC MLXIP 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002F74F1 MLXIP 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000753AD MLXIP 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000821E0 MLXIP 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000008A99 MLXIP 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000016FD1A MLXIP 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000013ABA3 MLXIP 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000221168 MLXIP 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075B0F6 MLXIP 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000CC005 MLXIP 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005CC20C MLXIP 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 MLXIP 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000367985 MLXIP 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000475586 MLXIP 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001A122A MLXIP 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MLX MLXIP 25361965 interaction type N/A PTMCode2
MLXIP MLX 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
YWHAB MLXIP 12446771 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
XPO1 MLXIP 25348397 N/A physical interaction ComPPI
MTOR MLXIP 25348397 N/A physical interaction ComPPI
MLXIP MLX 11073985 12446771 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
MLXIP CNPY2 12826659 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
MLXIP PNKD 25348397 N/A physical interaction ComPPI
RAN MLXIP 24234451 30021884 physical association cross-linking study IntAct
H2BC9 MLXIP 24234451 30021884 physical association cross-linking study IntAct

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