Gene Information gene info

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GENE：TAOK2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TAOK2
FullNmae TAO kinase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16835
EnsembleID ENSG00000149930
Uniprot Q9UL54

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TAOK2 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TAOK2 GO:0001558,GO:0004674,GO:0004674,GO:0004674,GO:0004709,GO:0005515,GO:0005524,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0006468,GO:0006612,GO:0006915,GO:0006974,GO:0007095,GO:0007409,GO:0007409,GO:0008360,GO:0015629,GO:0016477,GO:0030036,GO:0030424,GO:0030659,GO:0031410,GO:0031434,GO:0031954,GO:0032147,GO:0032874,GO:0032956,GO:0038191,GO:0043005,GO:0043235,GO:0043410,GO:0043539,GO:0044294,GO:0044295,GO:0046330,GO:0046330,GO:0046777,GO:0048041,GO:0048156,GO:0050321,GO:0051403,GO:0106310,GO:0150019,GO:0150020

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TAOK2 hsa:9344 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TAOK2 MAP3K7 16893890 23180781 physical association anti tag coimmunoprecipitation InnateDB
TAOK2 MAP2K3 10497253 11279118 23180781 23331499 phosphorylation reaction,stimulation,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB,SignaLink,SignaLink
TAOK2 MAP2K6 10497253 11279118 18988627 23180781 23331499 phosphorylation reaction,stimulation,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB,SignaLink,SignaLink
TAOK2 TAOK2 10497253 10660600 11279118 26467481 phosphorylation reaction,bind,up-regulates activity N/A Signor
TAOK2 MAP2K4 10660600 23331499 stimulation N/A SignaLink
TAOK2 MAP2K7 10660600 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR TAOK2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 TAOK2 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 TAOK2 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 TAOK2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
EGR1 TAOK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TAOK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004E008F TAOK2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00005651EE TAOK2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC TAOK2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
TAOK2 MAP2K3 25361965 interaction type N/A PTMCode2
MAP2K3 TAOK2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MAPRE1 TAOK2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBB TAOK2 25348397 N/A physical interaction,in vitro ComPPI
NMUR2 TAOK2 25348397 N/A physical interaction ComPPI
GRB2 TAOK2 12577067 24234451 25348397 association pull down ComPPI,IntAct
TUBA4A TAOK2 12639963 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
ELK1 TAOK2 12665513 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PKM TAOK2 25348397 N/A protein kinase assay ComPPI
TUBA1A TAOK2 25348397 N/A physical interaction ComPPI
MAP2K6 TAOK2 10497253 11279118 14525934 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
TAOK2 MAP2K3 24234451 25241761 25348397 physical association physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,IntAct
TAOK2 MEGF10 12421765 14525934 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
TAOK2 MAP3K7 25348397 N/A physical interaction ComPPI
TAOK2 KLHL12 25348397 N/A physical interaction ComPPI
TAOK2 RCHY1 25348397 N/A physical interaction ComPPI
TAOK2 STK25 25348397 N/A physical interaction ComPPI
TAOK2 LTBR 25348397 N/A physical interaction ComPPI
TAOK2 SLC39A8 25348397 N/A physical interaction ComPPI
TAOK2 KCNS3 25348397 N/A physical interaction ComPPI
TAOK2 PCDHB16 25348397 N/A physical interaction ComPPI
TAOK2 TH 25348397 N/A physical interaction ComPPI
TAOK2 ZDHHC1 25348397 N/A physical interaction ComPPI
TAOK2 TNKS2 22153077 24234451 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
TAOK2 MAPRE3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAOK2 CIDEB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAOK2 BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
ABITRAM TAOK2 25348397 N/A physical interaction ComPPI
TAOK2 TUBB2A 12639963 14525934 N/A experimental interaction detection HPRD
MAP3K7 TAOK2 16893890 27898060 N/A N/A OmniPath
TAOK2 MAP3K7 16893890 27898060 N/A N/A OmniPath
TAOK2 MAP2K4 10660600 27898060 stimulant N/A OmniPath
TAOK2 STK4 23431053 27898060 stimulant N/A OmniPath
MAP2K3 TAOK2 10497253 11279118 25241761 27898060 9786855 N/A N/A OmniPath
TAOK2 MAP2K3 10497253 11279118 25241761 27898060 9786855 stimulant N/A OmniPath
TAOK2 STK3 23431053 27898060 stimulant N/A OmniPath
MAP2K6 TAOK2 10497253 11279118 25241761 27898060 N/A N/A OmniPath
TAOK2 MAP2K6 10497253 11279118 25241761 27898060 stimulant N/A OmniPath
TAOK2 MAP2K7 10660600 27898060 stimulant N/A OmniPath
TAOK2 ELK1 12665513 27898060 stimulant N/A OmniPath

Visualization










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