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GENE：NAMPT

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NAMPT
FullNmae nicotinamide phosphoribosyltransferase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30092
EnsembleID ENSG00000105835
Uniprot P43490

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NAMPT autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NAMPT GO:0005125,GO:0005515,GO:0005829,GO:0007165,GO:0007267,GO:0008284,GO:0009435,GO:0016607,GO:0030054,GO:0032922,GO:0034356,GO:0042802,GO:0045944,GO:0047280,GO:0047280,GO:0051770,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NAMPT hsa:10135 path:hsa00760 Nicotinate and nicotinamide metabolism - Homo sapiens (human)
NAMPT hsa:10135 path:hsa01100 Metabolic pathways - Homo sapiens (human)
NAMPT hsa:10135 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 NAMPT 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 NAMPT 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 NAMPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NAMPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NAMPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NAMPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NAMPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NAMPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NAMPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NAMPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NAMPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF NAMPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 NAMPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 NAMPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 NAMPT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CLOCK NAMPT 19299583 trascriptional regulation,stimulation inferred by curator TFlink
JUN NAMPT 16701870 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 NAMPT 16701870 trascriptional regulation,stimulation inferred by curator TFlink
RELA NAMPT 16701870 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 NAMPT 19193853 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EED18 NAMPT 23834033 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS00000B7E30 NAMPT 22815788 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase
URS000003ABC4 NAMPT 23922874 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000345DEB NAMPT 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000215483 NAMPT 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 NAMPT 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001919B0 NAMPT 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00005606AA NAMPT 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CUL5 NAMPT 25348397 N/A physical interaction ComPPI
FTL NAMPT 18486613 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
KEAP1 NAMPT 25348397 N/A physical interaction ComPPI
CD81 NAMPT 25348397 N/A physical interaction ComPPI
U2AF2 NAMPT 25348397 N/A physical interaction ComPPI
NTRK1 NAMPT 25348397 N/A physical interaction ComPPI
ADORA2A NAMPT 18486613 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NDRG1 NAMPT 25348397 N/A physical interaction ComPPI
MT-ND1 NAMPT 18486613 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
MAPK15 NAMPT 25348397 N/A physical interaction ComPPI
HSPB1 NAMPT 25348397 N/A physical interaction ComPPI
UBE2A NAMPT 25348397 N/A physical interaction ComPPI
CTSA NAMPT 25348397 N/A physical interaction ComPPI
UBE2L6 NAMPT 18486613 24234451 25348397 physical association two hybrid ComPPI,IntAct
HNRNPH1 NAMPT 25348397 N/A physical interaction ComPPI
MVD NAMPT 25348397 N/A physical interaction ComPPI
FBXW11 NAMPT 25348397 N/A physical interaction ComPPI
XPO7 NAMPT 24234451 25348397 29748336 physical association anti tag coimmunoprecipitation ComPPI,IntAct
HNRNPA1 NAMPT 25348397 N/A physical interaction ComPPI
AKT2 NAMPT 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GSR NAMPT 25348397 N/A physical interaction ComPPI
LGALS7 NAMPT 25348397 N/A physical interaction ComPPI
IL13RA2 NAMPT 25348397 N/A physical interaction ComPPI
FANCA NAMPT 25348397 N/A physical interaction ComPPI
NXF1 NAMPT 25348397 N/A physical interaction ComPPI
NAMPT IFITM3 18486613 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
NAMPT ANXA6 25348397 N/A physical interaction ComPPI
NAMPT SDHA 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
DDA1 NAMPT 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct

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