Gene Information gene info

GENE:OSBP

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol OSBP
FullNmae oxysterol binding protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8503
EnsembleID ENSG00000110048
Uniprot P22059

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
OSBP pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
OSBP autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
OSBP GO:0000139,GO:0005515,GO:0005654,GO:0005730,GO:0005737,GO:0005789,GO:0005794,GO:0005802,GO:0005829,GO:0005829,GO:0005829,GO:0005886,GO:0006686,GO:0006699,GO:0008142,GO:0015248,GO:0015248,GO:0015914,GO:0015918,GO:0016020,GO:0019904,GO:0030054,GO:0032367,GO:0032934,GO:0035627,GO:0035774,GO:0042531,GO:0043231,GO:0048471,GO:0070273,GO:0097038,GO:0120009,GO:0120015,GO:1904411

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR OSBP 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 OSBP 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 OSBP 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 OSBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA OSBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 OSBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 OSBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 OSBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS OSBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A OSBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 OSBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 OSBP 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000017EA6A OSBP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000031B6ED OSBP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000C4DB5 OSBP 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00005F1B8C OSBP 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C OSBP 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5FFC OSBP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA OSBP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001067D1 OSBP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB OSBP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A OSBP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B OSBP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC OSBP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB OSBP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 OSBP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000519450 OSBP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005606AA OSBP 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRKD1 OSBP 22135298 phosphorylation N/A PhosphoSite
OSBP VAPA 25361965 interaction type N/A PTMCode2
VAPA OSBP 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GNAI3 OSBP 25348397 N/A physical interaction ComPPI
NPM1 OSBP 25348397 N/A physical interaction ComPPI
PPFIA1 OSBP 25348397 N/A physical interaction ComPPI
RAD21 OSBP 25348397 N/A physical interaction ComPPI
SWAP70 OSBP 25348397 N/A physical interaction ComPPI
H4C1 OSBP 25348397 N/A physical interaction ComPPI
SP1 OSBP 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
VAPA OSBP 12023275 14525934 24234451 25348397 25681634 26496610 27898060 29997244 association,physical association anti tag coimmunoprecipitation,bioluminescence resonance energy transfer,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,bimolecular fluorescence complementation,two hybrid ComPPI,HPRD,IntAct,OmniPath
OSBP ELAVL1 25348397 N/A physical interaction ComPPI
OSBP CSNK2A1 22113938 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
OSBP CAND1 25348397 N/A physical interaction ComPPI
OSBP CORO1B 25348397 N/A physical interaction ComPPI
OSBP CTNNA1 25348397 N/A physical interaction ComPPI
OSBP EIF4B 25348397 N/A physical interaction ComPPI
OSBP GARS1 25348397 N/A physical interaction ComPPI
OSBP GFPT1 25348397 N/A physical interaction ComPPI
OSBP KCTD12 25348397 N/A physical interaction ComPPI
OSBP NAP1L1 25348397 N/A physical interaction ComPPI
OSBP NARS1 25348397 N/A physical interaction ComPPI
OSBP PARVA 25348397 N/A physical interaction ComPPI
OSBP PRMT3 25348397 N/A physical interaction ComPPI
OSBP SAMHD1 25348397 N/A physical interaction ComPPI
OSBP SEC23A 25348397 N/A physical interaction ComPPI
OSBP SF1 25348397 N/A physical interaction ComPPI
OSBP TBC1D17 25348397 N/A physical interaction ComPPI
OSBP USP11 25348397 N/A physical interaction ComPPI
OSBP ZRANB2 25348397 N/A physical interaction ComPPI
OSBP VAPB 25348397 N/A physical interaction ComPPI
OSBP FKBP6 24234451 25036637 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction,luminescence based mammalian interactome mapping ComPPI,IntAct
OSBP NXF1 25348397 N/A physical interaction ComPPI
OSBP EGFR 25348397 N/A physical interaction ComPPI
OSBP LRRC46 25348397 N/A physical interaction ComPPI
OSBP BTN2A1 25348397 N/A physical interaction ComPPI
OSBP BTNL8 25348397 N/A physical interaction ComPPI
OSBP NTRK1 25348397 N/A physical interaction ComPPI
OSBP TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
OSBP TMEM216 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
OSBP ZNRF4 25348397 N/A physical interaction ComPPI
OSBP SERPINB2 25348397 N/A physical interaction ComPPI
OSBP CDH5 25348397 N/A physical interaction ComPPI
OSBP PCDHB16 25348397 N/A physical interaction ComPPI
OSBP LRRTM1 25348397 N/A physical interaction ComPPI
OSBP PCDHGA5 25348397 N/A physical interaction ComPPI
TTC1 OSBP 25348397 N/A physical interaction ComPPI
XPO7 OSBP 25348397 N/A physical interaction ComPPI
B2M OSBP 24234451 30021884 physical association cross-linking study IntAct
PRKD1 OSBP 21285358 27898060 inhibition N/A OmniPath

Visualization