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GENE：PAFAH1B1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PAFAH1B1
FullNmae platelet activating factor acetylhydrolase 1b regulatory subunit 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8574
EnsembleID ENSG00000007168
Uniprot P43034

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PAFAH1B1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PAFAH1B1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PAFAH1B1 GO:0000132,GO:0000132,GO:0000226,GO:0000235,GO:0000776,GO:0000776,GO:0001667,GO:0001675,GO:0001764,GO:0001764,GO:0001961,GO:0005515,GO:0005635,GO:0005635,GO:0005813,GO:0005813,GO:0005829,GO:0005829,GO:0005871,GO:0005875,GO:0005875,GO:0005881,GO:0005938,GO:0007017,GO:0007097,GO:0007254,GO:0007268,GO:0007281,GO:0007405,GO:0007611,GO:0008017,GO:0008090,GO:0008090,GO:0008201,GO:0008247,GO:0008344,GO:0009306,GO:0010977,GO:0016042,GO:0017145,GO:0019226,GO:0021540,GO:0021766,GO:0021819,GO:0021895,GO:0021987,GO:0030036,GO:0031023,GO:0031023,GO:0031252,GO:0031514,GO:0031965,GO:0032420,GO:0034452,GO:0036035,GO:0038026,GO:0040019,GO:0042249,GO:0042802,GO:0043005,GO:0043025,GO:0043274,GO:0043622,GO:0045505,GO:0045773,GO:0045931,GO:0046329,GO:0046469,GO:0046982,GO:0047496,GO:0047496,GO:0048471,GO:0048854,GO:0048854,GO:0050804,GO:0050885,GO:0051010,GO:0051012,GO:0051081,GO:0051219,GO:0051660,GO:0051661,GO:0060117,GO:0061003,GO:0070062,GO:0070507,GO:0070840,GO:0070840,GO:0090102,GO:0090176,GO:0090724,GO:0097529,GO:0098685,GO:0098978,GO:0140650,GO:1904115,GO:1904936

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PAFAH1B1 hsa:5048 path:hsa00565 Ether lipid metabolism - Homo sapiens (human)
PAFAH1B1 hsa:5048 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ISG15 PAFAH1B1 16009940 23180781 physical association unspecified method InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 PAFAH1B1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 PAFAH1B1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PAFAH1B1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 PAFAH1B1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 PAFAH1B1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PAFAH1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PAFAH1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PAFAH1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PAFAH1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PAFAH1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PAFAH1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PAFAH1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PAFAH1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SP1 PAFAH1B1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 PAFAH1B1 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS00000F31F4 PAFAH1B1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 PAFAH1B1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000035CC3E PAFAH1B1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00001A405B PAFAH1B1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016D2D4 PAFAH1B1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004AC389 PAFAH1B1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000003FD55 PAFAH1B1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D PAFAH1B1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 PAFAH1B1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000277201 PAFAH1B1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE PAFAH1B1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 PAFAH1B1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 PAFAH1B1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA PAFAH1B1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F PAFAH1B1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 PAFAH1B1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 PAFAH1B1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 PAFAH1B1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 PAFAH1B1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 PAFAH1B1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C PAFAH1B1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D PAFAH1B1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000204177 PAFAH1B1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000246356 PAFAH1B1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075A513 PAFAH1B1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000010F787 PAFAH1B1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C48FA PAFAH1B1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004B4B85 PAFAH1B1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003575B PAFAH1B1 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PAFAH1B3 PAFAH1B1 25361965 interaction type N/A PTMCode2
PAFAH1B1 PAFAH1B3 25361965 interaction type N/A PTMCode2
PAFAH1B1 DCTN2 25361965 interaction type N/A PTMCode2
DCTN2 PAFAH1B1 25361965 interaction type N/A PTMCode2
RAF1 PAFAH1B1 25361965 interaction type N/A PTMCode2
PAFAH1B1 RAF1 25361965 interaction type N/A PTMCode2
NDE1 PAFAH1B1 25361965 interaction type N/A PTMCode2
PAFAH1B1 NDE1 25361965 interaction type N/A PTMCode2
CSNK2A1 PAFAH1B1 25361965 interaction type N/A PTMCode2
PAFAH1B1 CSNK2A1 25361965 interaction type N/A PTMCode2
MAP2 PAFAH1B1 25361965 interaction type N/A PTMCode2
PAFAH1B1 MAP2 25361965 interaction type N/A PTMCode2
DAB1 PAFAH1B1 25361965 interaction type N/A PTMCode2
PAFAH1B1 DAB1 25361965 interaction type N/A PTMCode2
DYNC1H1 PAFAH1B1 25361965 interaction type N/A PTMCode2
PAFAH1B1 DYNC1H1 25361965 interaction type N/A PTMCode2
NUDC PAFAH1B1 25361965 interaction type N/A PTMCode2
PAFAH1B1 NUDC 25361965 interaction type N/A PTMCode2
DCTN1 PAFAH1B1 25361965 interaction type N/A PTMCode2
PAFAH1B1 DCTN1 25361965 interaction type N/A PTMCode2
DCX PAFAH1B1 25361965 interaction type N/A PTMCode2
PAFAH1B1 DCX 25361965 interaction type N/A PTMCode2
NDEL1 PAFAH1B1 25361965 interaction type N/A PTMCode2
PAFAH1B1 NDEL1 25361965 interaction type N/A PTMCode2
CENPF PAFAH1B1 25361965 interaction type N/A PTMCode2
PAFAH1B1 CENPF 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MAPRE1 PAFAH1B1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DYNLL1 PAFAH1B1 25348397 N/A physical interaction ComPPI
HSPA8 PAFAH1B1 24234451 25348397 25910212 association anti tag coimmunoprecipitation ComPPI,IntAct
PAK2 PAFAH1B1 25348397 N/A physical interaction ComPPI
ISG15 PAFAH1B1 25348397 N/A physical interaction ComPPI
SNRPF PAFAH1B1 25348397 N/A physical interaction ComPPI
NUDCD3 PAFAH1B1 16754861 24234451 25348397 physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
YWHAG PAFAH1B1 25348397 N/A physical interaction ComPPI
KEAP1 PAFAH1B1 25348397 N/A physical interaction ComPPI
HSP90AB1 PAFAH1B1 24234451 25348397 25910212 association anti tag coimmunoprecipitation ComPPI,IntAct
EIF5 PAFAH1B1 25348397 N/A physical interaction ComPPI
DYNC1LI1 PAFAH1B1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
HSP90AA1 PAFAH1B1 20133715 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
NTRK1 PAFAH1B1 25348397 N/A physical interaction ComPPI
DAB1 PAFAH1B1 14525934 14578885 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
DYNLT3 PAFAH1B1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PDIA4 PAFAH1B1 25348397 N/A physical interaction ComPPI
MAP2 PAFAH1B1 25348397 N/A in vitro ComPPI
CSNK2A1 PAFAH1B1 10491172 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
DCTN1 PAFAH1B1 11889140 14525934 14584027 24234451 25348397 26638075 association,physical association experimental interaction detection,physical interaction,in vivo,proximity-dependent biotin identification,inference by socio-affinity scoring ComPPI,HPRD,IntAct
NDE1 PAFAH1B1 11163258 14525934 24234451 25348397 27173435 association,physical association two hybrid,experimental interaction detection,physical interaction,in vivo,tandem affinity purification,inference by socio-affinity scoring,two hybrid ComPPI,HPRD,IntAct
CEP135 PAFAH1B1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PDE4D PAFAH1B1 25348397 N/A physical interaction ComPPI
BICD2 PAFAH1B1 25348397 N/A physical interaction ComPPI
TNIK PAFAH1B1 25348397 N/A physical interaction ComPPI
PAFAH1B1 DCX 11001923 12885786 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
PAFAH1B1 PAFAH1B2 10727864 14525934 24234451 25348397 27173435 association,physical association two hybrid,experimental interaction detection,physical interaction,in vitro,tandem affinity purification,inference by socio-affinity scoring,two hybrid ComPPI,HPRD,IntAct
PAFAH1B1 DNAI1 11889140 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PAFAH1B1 NDEL1 10931877 11163260 14525934 24234451 25348397 27173435 association,physical association two hybrid,experimental interaction detection,physical interaction,in vivo,tandem affinity purification,inference by socio-affinity scoring,two hybrid ComPPI,HPRD,IntAct
PAFAH1B1 HSPH1 14525934 14733918 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PAFAH1B1 NUDC 11734602 12885786 14525934 20675372 25348397 27898060 9601647 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
PAFAH1B1 MAP1B 14525934 15762842 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
PAFAH1B1 TUBA1A 14525934 25348397 9384577 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PAFAH1B1 KARS1 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PAFAH1B1 DCTN2 25348397 N/A physical interaction ComPPI
PAFAH1B1 DYNC1H1 24234451 25348397 26496610 27173435 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PAFAH1B1 CLIP1 11940666 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
PAFAH1B1 DISC1 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PAFAH1B1 CDK2 25348397 N/A physical interaction ComPPI
PAFAH1B1 HSP90AA2P 25348397 N/A physical interaction ComPPI
PAFAH1B1 DYNC1I1 25348397 N/A physical interaction ComPPI
PAFAH1B1 KATNA1 25348397 N/A physical interaction ComPPI
PAFAH1B1 KATNB1 25348397 N/A physical interaction ComPPI
PAFAH1B1 NUDCD2 20133715 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
PAFAH1B1 PDE4B 25348397 N/A physical interaction ComPPI
PAFAH1B1 IQCB1 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PAFAH1B1 ASNS 25348397 N/A physical interaction ComPPI
PAFAH1B1 ATIC 25348397 N/A physical interaction ComPPI
PAFAH1B1 CAPN2 25348397 N/A physical interaction ComPPI
PAFAH1B1 FH 25348397 N/A physical interaction ComPPI
PAFAH1B1 MSN 25348397 N/A physical interaction ComPPI
PAFAH1B1 MYO1E 25348397 N/A physical interaction ComPPI
PAFAH1B1 PAPSS1 25348397 N/A physical interaction ComPPI
PAFAH1B1 SNRPD2 25348397 N/A physical interaction ComPPI
PAFAH1B1 TATDN1 25348397 N/A physical interaction ComPPI
PAFAH1B1 UBXN1 25348397 N/A physical interaction ComPPI
PAFAH1B1 YWHAH 25348397 N/A physical interaction ComPPI
PAFAH1B1 AP1G1 25348397 N/A physical interaction ComPPI
PAFAH1B1 CHID1 25348397 N/A physical interaction ComPPI
PAFAH1B1 CHMP2B 25348397 N/A physical interaction ComPPI
PAFAH1B1 CSTF1 25348397 N/A physical interaction ComPPI
PAFAH1B1 SBDS 25348397 N/A physical interaction ComPPI
PAFAH1B1 SCLY 25348397 N/A physical interaction ComPPI
PAFAH1B1 CEP128 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PAFAH1B1 DYNC1I2 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PAFAH1B1 DYNLT1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PAFAH1B1 DYNLT2B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PAFAH1B1 GID8 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PAFAH1B1 MAPRE2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PAFAH1B1 DYNLRB2 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PAFAH1B1 AHI1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PAFAH1B1 TRIM25 25348397 N/A physical interaction ComPPI
PAFAH1B1 CENPF 17600710 24234451 25348397 colocalization fluorescence technology ComPPI,IntAct
PAFAH1B1 BET1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PAFAH1B3 PAFAH1B1 10727864 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
CAPNS1 PAFAH1B1 25348397 N/A physical interaction ComPPI
WDR5 PAFAH1B1 25348397 N/A physical interaction ComPPI
ISOC1 PAFAH1B1 25348397 N/A physical interaction ComPPI
HMGB3 PAFAH1B1 25348397 N/A physical interaction ComPPI
PAFAH1B1 PAFAH1B1 11889140 14525934 N/A experimental interaction detection HPRD
TANK PAFAH1B1 24234451 30561431 association virotrap IntAct
HSP90AA1 PAFAH1B1 20133715 20675372 27898060 stimulant N/A OmniPath
ISG15 PAFAH1B1 16009940 27898060 N/A N/A OmniPath
PAFAH1B1 CLIP1 11940666 12885786 27898060 stimulant N/A OmniPath
NUDCD2 PAFAH1B1 20133715 27898060 stimulant N/A OmniPath
DISC1 PAFAH1B1 17043677 17202468 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00008B69AE PAFAH1B1 27087310 direct interaction,inhibition N/A NPInter
URS00009C5D05 PAFAH1B1 27087310 direct interaction,inhibition N/A NPInter

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