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GENE：PDE4DIP

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PDE4DIP
FullNmae phosphodiesterase 4D interacting protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15580
EnsembleID ENSG00000178104
Uniprot Q5VU43

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PDE4DIP pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PDE4DIP autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PDE4DIP GO:0005515,GO:0005634,GO:0005737,GO:0005794,GO:0005794,GO:0005794,GO:0005813,GO:0005813,GO:0005813,GO:0007098,GO:0019899,GO:0030016,GO:0060090,GO:0060090,GO:0065003,GO:0090063,GO:1903358,GO:1903358

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TRAF4 PDE4DIP 16969126 23180781 physical association two hybrid InnateDB
TRAF3 PDE4DIP 22792062 23180781 physical association anti tag coimmunoprecipitation InnateDB
USO1 PDE4DIP 22792062 23180781 physical association anti tag coimmunoprecipitation InnateDB
RNF2 PDE4DIP 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
BYSL PDE4DIP 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
AR PDE4DIP 18971253 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ESR1 PDE4DIP 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PDE4DIP 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PDE4DIP 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 PDE4DIP 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 PDE4DIP 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PDE4DIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PDE4DIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PDE4DIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PDE4DIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PDE4DIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PDE4DIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 PDE4DIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PDE4DIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PDE4DIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PDE4DIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PDE4DIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PDE4DIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PDE4DIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 PDE4DIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PDE4DIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYB PDE4DIP N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000017EA6A PDE4DIP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000077AED PDE4DIP 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS00002E0524 PDE4DIP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005DEC41 PDE4DIP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000BF7F9 PDE4DIP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000039607D PDE4DIP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000105D19 PDE4DIP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000052EA98 PDE4DIP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000101787 PDE4DIP 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000B0E50 PDE4DIP 22012620 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000023BE29 PDE4DIP 22012620 23706177 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000003ABC4 PDE4DIP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004AF715 PDE4DIP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000075E2C3 PDE4DIP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF PDE4DIP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000224AEA PDE4DIP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 PDE4DIP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000075D2F5 PDE4DIP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00003D4175 PDE4DIP 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PDE4DIP LMO4 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP BYSL 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP RTP5 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP MAPRE1 24234451 25348397 25416956 26496610 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP UTP14C 25348397 N/A two hybrid,physical interaction ComPPI
PDE4DIP LENG1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP ZNF408 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP CHCHD3 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP ZNF581 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP PDE4D 11134006 25348397 27898060 N/A two hybrid,physical interaction,in vivo ComPPI,OmniPath
PDE4DIP GFI1B 25348397 N/A two hybrid,physical interaction ComPPI
PDE4DIP CDC5L 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDE4DIP TNIK 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDE4DIP OSGEP 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDE4DIP GADD45G 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDE4DIP NEK2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDE4DIP SNCA 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDE4DIP FES 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDE4DIP TK1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDE4DIP FHL1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDE4DIP CDKN1A 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDE4DIP LAMTOR3 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDE4DIP KRAS 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDE4DIP SMN1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDE4DIP IMMT 21900206 24234451 25348397 30021884 physical association two hybrid,cross-linking study,physical interaction ComPPI,IntAct
PDE4DIP PFDN1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDE4DIP ITSN2 25348397 N/A physical interaction ComPPI
PDE4DIP ELAVL1 25348397 N/A physical interaction ComPPI
PDE4DIP TRAF4 25348397 N/A physical interaction ComPPI
PDE4DIP PRNP 25348397 N/A physical interaction ComPPI
PDE4DIP PRNP 18482256 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
PDE4DIP ZNF512B 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDE4DIP USO1 25348397 N/A physical interaction ComPPI
PDE4DIP KRT18 21988832 24234451 25348397 colocalization,physical association two hybrid,physical interaction,confocal microscopy ComPPI,IntAct
PDE4DIP PIAS4 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDE4DIP ADH1B 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PDE4DIP KDM1A 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDE4DIP PRKACA 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PDE4DIP PRKACB 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PDE4DIP ANKRD11 25348397 N/A physical interaction ComPPI
PDE4DIP ARNT2 25348397 N/A physical interaction ComPPI
PDE4DIP KRT31 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PDE4DIP NEFL 25348397 N/A physical interaction ComPPI
PDE4DIP SDCBP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP ZSCAN26 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP NAA10 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP FCHSD2 25348397 N/A physical interaction ComPPI
PDE4DIP MTUS2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP TFIP11 25348397 N/A physical interaction ComPPI
PDE4DIP PRPF31 24234451 25348397 25416956 25910212 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP C1ORF109 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP CCDC198 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP SHFL 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP VAC14 25348397 N/A physical interaction ComPPI
PDE4DIP MIF4GD 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP CCDC146 25348397 N/A physical interaction ComPPI
PDE4DIP SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP AEN 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP SCNM1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP ZFYVE21 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP FAM161A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP KLC4 25348397 N/A physical interaction ComPPI
PDE4DIP HAUS1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP KLC3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP PPP1R18 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP ZBTB38 25348397 N/A physical interaction ComPPI
PDE4DIP RNF2 25348397 N/A physical interaction ComPPI
PDE4DIP MLF1 25348397 N/A physical interaction ComPPI
PDE4DIP CEP170 25348397 N/A physical interaction ComPPI
PDE4DIP PRKAR2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDE4DIP SCCPDH 25348397 N/A physical interaction ComPPI
PDE4DIP TEAD4 25348397 N/A physical interaction ComPPI
PDE4DIP DYNLL1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDE4DIP PM20D1 25348397 N/A physical interaction ComPPI
PDE4DIP A2ML1 25348397 N/A physical interaction ComPPI
PDE4DIP AKAP9 25348397 N/A physical interaction ComPPI
PDE4DIP NIBAN2 25348397 N/A physical interaction ComPPI
PDE4DIP CSNK1D 25348397 N/A physical interaction ComPPI
PDE4DIP PRKACG 25348397 N/A physical interaction ComPPI
PDE4DIP LCN2 25348397 N/A physical interaction ComPPI
PDE4DIP CD207 25348397 N/A physical interaction ComPPI
PDE4DIP CSNK1E 25348397 N/A physical interaction ComPPI
PDE4DIP IVL 25348397 N/A physical interaction ComPPI
PDE4DIP NDRG1 25348397 N/A physical interaction ComPPI
PDE4DIP EVPL 25348397 N/A physical interaction ComPPI
PDE4DIP ANXA8 25348397 N/A physical interaction ComPPI
PDE4DIP C3 25348397 N/A physical interaction ComPPI
PDE4DIP CRABP2 25348397 N/A physical interaction ComPPI
PDE4DIP TYMP 25348397 N/A physical interaction ComPPI
PDE4DIP DNAJC10 25348397 N/A physical interaction ComPPI
PDE4DIP CCDC6 25348397 N/A physical interaction ComPPI
PDE4DIP CDK5RAP2 25348397 N/A physical interaction ComPPI
PDE4DIP ALDH1A3 25348397 N/A physical interaction ComPPI
PDE4DIP ZNF785 25348397 N/A physical interaction ComPPI
PDE4DIP RAB25 25348397 N/A physical interaction ComPPI
PDE4DIP GATM 25348397 N/A physical interaction ComPPI
PDE4DIP SERPINB4 25348397 N/A physical interaction ComPPI
PDE4DIP S100A7 25348397 N/A physical interaction ComPPI
PDE4DIP CALML3 25348397 N/A physical interaction ComPPI
PDE4DIP MAPRE3 25348397 N/A physical interaction ComPPI
PDE4DIP ACADVL 25348397 N/A physical interaction ComPPI
PDE4DIP PKP3 25348397 N/A physical interaction ComPPI
PDE4DIP C1ORF87 25348397 N/A physical interaction ComPPI
PDE4DIP AKR1B10 25348397 N/A physical interaction ComPPI
PDE4DIP PPL 25348397 N/A physical interaction ComPPI
PDE4DIP S100A9 25348397 N/A physical interaction ComPPI
PDE4DIP JUP 25348397 N/A physical interaction ComPPI
PDE4DIP TGM1 25348397 N/A physical interaction ComPPI
PDE4DIP LGALS7 25348397 N/A physical interaction ComPPI
PDE4DIP POF1B 25348397 N/A physical interaction ComPPI
PDE4DIP SERPINB5 25348397 N/A physical interaction ComPPI
PDE4DIP CST6 25348397 N/A physical interaction ComPPI
PDE4DIP GM2A 25348397 N/A physical interaction ComPPI
PDE4DIP ARF6 25348397 N/A physical interaction ComPPI
PDE4DIP HMGCS2 25348397 N/A physical interaction ComPPI
PDE4DIP GDPD3 25348397 N/A physical interaction ComPPI
PDE4DIP NCCRP1 25348397 N/A physical interaction ComPPI
PDE4DIP SERPINB3 25348397 N/A physical interaction ComPPI
PDE4DIP CALML5 25348397 N/A physical interaction ComPPI
PDE4DIP CYLD 25348397 N/A physical interaction ComPPI
PDE4DIP UBE2J2 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
PDE4DIP AKTIP 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
PDE4DIP CLIP4 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
PDE4DIP MYBPC2 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
PDE4DIP PYGM 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
PDE4DIP TULP3 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
PDE4DIP GOLGA8F 24234451 25348397 25416956 physical association two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP GOLGA8DP 24234451 25348397 25416956 physical association two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP FAM74A4 24234451 25348397 25416956 physical association two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDE4DIP BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
NPM1 PDE4DIP 24234451 30021884 physical association cross-linking study IntAct
H2BC9 PDE4DIP 24234451 30021884 physical association cross-linking study IntAct
PDE4DIP PRKAR2A 21569246 27898060 stimulant N/A OmniPath
PDE4DIP PRKAR1A 21569246 27898060 stimulant N/A OmniPath
PDE4DIP MYBPC3 21569246 27898060 stimulant N/A OmniPath

Visualization










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