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GENE：PITX1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PITX1
FullNmae paired like homeodomain 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9004
EnsembleID ENSG00000069011
Uniprot P78337

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PITX1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PITX1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PITX1 GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0001228,GO:0001501,GO:0003700,GO:0005515,GO:0005634,GO:0005634,GO:0005667,GO:0005737,GO:0006357,GO:0009653,GO:0014707,GO:0021983,GO:0035116,GO:0045892,GO:0045944,GO:0048625,GO:0051216,GO:0061629,GO:1990837

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IRF7 PITX1 12242290 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 PITX1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 PITX1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PITX1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 PITX1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 PITX1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PITX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PITX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PITX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PITX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PITX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PITX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PITX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PITX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PITX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PITX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001597DC PITX1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD PITX1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D PITX1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002373FD PITX1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000018D2BE PITX1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000086A4D PITX1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000028DE3F PITX1 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PITX1 NEUROD1 25361965 interaction type N/A PTMCode2
NEUROD1 PITX1 25361965 interaction type N/A PTMCode2
PITX1 NR5A1 25361965 interaction type N/A PTMCode2
NR5A1 PITX1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
RBPMS PITX1 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
GOLGA2 PITX1 24234451 25348397 25910212 physical association two hybrid array,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
ARID5A PITX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HOXA1 PITX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RHOXF2 PITX1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
CDX4 PITX1 25348397 N/A physical interaction ComPPI
ROR2 PITX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT83 PITX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IPO13 PITX1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 PITX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRTAP19-5 PITX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRTAP8-1 PITX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LZTS2 PITX1 25348397 N/A physical interaction ComPPI
KRTAP26-1 PITX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TP53BP1 PITX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRR20E PITX1 25348397 N/A physical interaction ComPPI
PRR20C PITX1 25348397 N/A physical interaction ComPPI
PRR20D PITX1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NR5A1 PITX1 10369682 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
TRAPPC2B PITX1 25348397 N/A physical interaction ComPPI
RFX6 PITX1 25348397 N/A physical interaction ComPPI
PITX1 POU1F1 14525934 25348397 27898060 8755540 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
PITX1 NEUROD1 14525934 25348397 27898060 9343431 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
PITX1 DVL3 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
PITX1 EGR1 10082522 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
PITX1 SMARCA2 25348397 N/A physical interaction ComPPI
PITX1 SMAD3 25348397 N/A physical interaction ComPPI
PITX1 UPF2 25348397 N/A physical interaction ComPPI
PITX1 ALG13 25348397 N/A physical interaction ComPPI
PITX1 C1ORF94 25348397 N/A physical interaction ComPPI
PITX1 HGS 25348397 N/A physical interaction ComPPI
PITX1 MAGED1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 MGAT5B 25348397 N/A physical interaction ComPPI
PITX1 PLSCR1 25348397 N/A physical interaction ComPPI
PITX1 RNF31 25348397 N/A physical interaction ComPPI
PITX1 SPAG8 25348397 N/A physical interaction ComPPI
PITX1 TRIM23 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 ZBTB32 25348397 N/A physical interaction ComPPI
PITX1 TRAPPC2 25348397 N/A physical interaction ComPPI
PITX1 EWSR1 25348397 N/A physical interaction ComPPI
PITX1 XPO1 25348397 N/A physical interaction ComPPI
PITX1 FOXO1 25348397 N/A physical interaction ComPPI
PITX1 TFAP2D 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 BPIFA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 PLSCR3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 TBX22 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 MSX2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 CLUHP3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 LINC00518 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 SLC15A2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 TRAF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 C11ORF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 KRT34 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 CYSRT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 SERGEF 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 MYOZ3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 KRTAP3-3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 DZIP3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 PFDN5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 NHLRC4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 STH 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 TEKT5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 PTK6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 KLHL26 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 PLA2G10 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 LINC01555 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 UFSP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 C10ORF55 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 KRTAP13-2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 KRTAP7-1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 METTL27 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 KRTAP6-2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 SIK1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 TBX19 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 CEACAM6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 SERPINE1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 AKAP8L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 KRTAP6-1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PITX1 MDFI 24234451 25348397 25910212 physical association two hybrid array,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
KRTAP19-7 PITX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DDIT4L PITX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IRF7 PITX1 12242290 27898060 N/A N/A OmniPath

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