GENE:PYCARD
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | PYCARD |
FullNmae | PYD and CARD domain containing |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:16608 |
EnsembleID | ENSG00000103490 |
Uniprot | Q9ULZ3 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
PYCARD | pyroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
PYCARD | pyroptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
PYCARD | parthanatos | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
PYCARD | necroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
PYCARD | necroptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
PYCARD | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
PYCARD | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
PYCARD | autophagy | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
PYCARD | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
PYCARD | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
PYCARD | GO:0000139,GO:0001773,GO:0002020,GO:0002218,GO:0002221,GO:0002230,GO:0002277,GO:0002588,GO:0002821,GO:0005138,GO:0005515,GO:0005523,GO:0005576,GO:0005634,GO:0005654,GO:0005730,GO:0005730,GO:0005737,GO:0005737,GO:0005739,GO:0005783,GO:0005829,GO:0005829,GO:0005874,GO:0006915,GO:0006919,GO:0006919,GO:0006954,GO:0007165,GO:0007231,GO:0008385,GO:0008656,GO:0010506,GO:0010803,GO:0017024,GO:0019899,GO:0030838,GO:0031647,GO:0032088,GO:0032090,GO:0032688,GO:0032722,GO:0032729,GO:0032731,GO:0032731,GO:0032731,GO:0032731,GO:0032733,GO:0032755,GO:0032755,GO:0032757,GO:0032760,GO:0032991,GO:0033209,GO:0034774,GO:0035578,GO:0042104,GO:0042771,GO:0042802,GO:0042802,GO:0042803,GO:0043025,GO:0043065,GO:0043124,GO:0043280,GO:0043280,GO:0044325,GO:0044351,GO:0044546,GO:0045087,GO:0046330,GO:0046456,GO:0046983,GO:0050729,GO:0050729,GO:0050729,GO:0050766,GO:0050829,GO:0050830,GO:0050870,GO:0051091,GO:0051092,GO:0051260,GO:0051607,GO:0051607,GO:0060907,GO:0061702,GO:0061702,GO:0061702,GO:0070269,GO:0070374,GO:0070700,GO:0071222,GO:0071347,GO:0071356,GO:0071901,GO:0072332,GO:0072558,GO:0072558,GO:0072559,GO:0072559,GO:0090200,GO:0097169,GO:0097169,GO:0140738,GO:1900016,GO:1901224,GO:2000406,GO:2001056,GO:2001238,GO:2001242 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
PYCARD | hsa:29108 | path:hsa04217 | Necroptosis - Homo sapiens (human) |
PYCARD | hsa:29108 | path:hsa04621 | NOD-like receptor signaling pathway - Homo sapiens (human) |
PYCARD | hsa:29108 | path:hsa04623 | Cytosolic DNA-sensing pathway - Homo sapiens (human) |
PYCARD | hsa:29108 | path:hsa04625 | C-type lectin receptor signaling pathway - Homo sapiens (human) |
PYCARD | hsa:29108 | path:hsa05130 | Pathogenic Escherichia coli infection - Homo sapiens (human) |
PYCARD | hsa:29108 | path:hsa05131 | Shigellosis - Homo sapiens (human) |
PYCARD | hsa:29108 | path:hsa05132 | Salmonella infection - Homo sapiens (human) |
PYCARD | hsa:29108 | path:hsa05133 | Pertussis - Homo sapiens (human) |
PYCARD | hsa:29108 | path:hsa05134 | Legionellosis - Homo sapiens (human) |
PYCARD | hsa:29108 | path:hsa05135 | Yersinia infection - Homo sapiens (human) |
PYCARD | hsa:29108 | path:hsa05164 | Influenza A - Homo sapiens (human) |
PYCARD | hsa:29108 | path:hsa05417 | Lipid and atherosclerosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
PYCARD | AIM2 | 19104081 19158675 19158676 21575908 23180781 23702978 26192618 26885855 27048821 27066895 27984721 | interaction type,physical association | anti tag coimmunoprecipitation,pull down | ACSN,InnateDB |
PYCARD | NLRC4 | 11967258 14634131 19104081 19337385 23180781 23702978 23940371 24803432 26192618 26885855 27048821 27066895 27984721 | interaction type,physical association | anti tag coimmunoprecipitation,two hybrid,gst pull down,pull down,fluorescence microscopy | ACSN,InnateDB |
PYCARD | NLRP3 | 11989976 12615073 15030775 17959595 19104081 19158675 19337385 20385749 21575908 23180781 23202296 23702978 24803432 26192618 26885855 27048821 27066895 27439607 27984721 | interaction type,physical association | anti tag coimmunoprecipitation,two hybrid,fluorescence microscopy | ACSN,InnateDB |
PYCARD | BAX | 14730312 19062087 19104081 19968986 23180781 26192618 26885855 27048821 27066895 27984721 | interaction type,physical association | anti tag coimmunoprecipitation,pull down | ACSN,InnateDB |
RHO | PYCARD | 24919149 26192618 26885855 27048821 27066895 | interaction type | N/A | ACSN |
PYCARD | IL1B | 19104081 20385749 23180781 23202296 24803432 26192618 26885855 27048821 27066895 27439607 27984721 | interaction type,physical association | fluorescence microscopy | ACSN,InnateDB |
P2RX7 | PYCARD | 20086177 26192618 | interaction type | N/A | ACSN |
CD14 | PYCARD | 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 26192618 9743347 | interaction type | N/A | ACSN |
IRAK2 | PYCARD | 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 26192618 9743347 | interaction type | N/A | ACSN |
IRAK4 | PYCARD | 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 26192618 9743347 | interaction type | N/A | ACSN |
LY96 | PYCARD | 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 26192618 9743347 | interaction type | N/A | ACSN |
MYD88 | PYCARD | 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 26192618 9743347 | interaction type | N/A | ACSN |
TIRAP | PYCARD | 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 26192618 9743347 | interaction type | N/A | ACSN |
PYCARD | CASP1 | 11967258 14634131 16585594 19337385 21385879 23180781 24803432 | physical association | anti tag coimmunoprecipitation,two hybrid,gst pull down,pull down,fluorescence microscopy | InnateDB |
RIPK2 | PYCARD | 14634131 23180781 | physical association | anti tag coimmunoprecipitation,gst pull down | InnateDB |
PYCARD | NLRP2 | 15030775 15456791 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
NLRP3 | PYCARD | 11786556 15030775 16037825 23180781 25686105 | physical association | affinity chromatography technology,anti tag coimmunoprecipitation,two hybrid | InnateDB |
NLRP2 | PYCARD | 15030775 23180781 23625868 | physical association | anti tag coimmunoprecipitation | InnateDB |
MEFV | PYCARD | 14595024 16037825 17431422 17964261 23180781 | physical association | affinity chromatography technology,anti tag coimmunoprecipitation,two hybrid | InnateDB |
PYCARD | NLRP10 | 15096476 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
PYCARD | PYDC1 | 12656673 17178784 18362139 19337385 23180781 | physical association | anti tag coimmunoprecipitation,two hybrid,pull down,surface plasmon resonance | InnateDB |
PYCARD | CHUK | 12486103 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
IKBKB | PYCARD | 12486103 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
TP53 | PYCARD | 14730312 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
NLRC4 | PYCARD | 12646168 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
PYCARD | PYCARD | 19337385 23180781 | physical association | two hybrid | InnateDB |
PYCARD | DDX58 | 19915568 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
NLRP1 | PYCARD | 21252346 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
PYCARD | IFI16 | 21575908 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
DHX33 | PYCARD | 23180781 23871209 | physical association | anti tag coimmunoprecipitation | InnateDB |
DDX58 | PYCARD | 23180781 23592984 | physical association | anti tag coimmunoprecipitation | InnateDB |
PYCARD | CASP8 | 23180781 24803432 | physical association | fluorescence microscopy | InnateDB |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
GATA2 | PYCARD | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
YBX1 | PYCARD | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
E2F4 | PYCARD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | PYCARD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS00000753AD | PYCARD | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000AA464 | PYCARD | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000221168 | PYCARD | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000235862 | PYCARD | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001012BC | PYCARD | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075C4B1 | PYCARD | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000049704B | PYCARD | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000006372A | PYCARD | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000C4DB5 | PYCARD | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002075FA | PYCARD | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002FF522 | PYCARD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000195F5B | PYCARD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000E7139 | PYCARD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000040828B | PYCARD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075BDA4 | PYCARD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004407DC | PYCARD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002CEB74 | PYCARD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000070B1D | PYCARD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003AA845 | PYCARD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
PYCARD | NLRP12 | 25361965 | interaction type | N/A | PTMCode2 |
NLRP12 | PYCARD | 25361965 | interaction type | N/A | PTMCode2 |
PYCARD | NLRC4 | 25361965 | interaction type | N/A | PTMCode2 |
NLRC4 | PYCARD | 25361965 | interaction type | N/A | PTMCode2 |
PYCARD | CARD16 | 25361965 | interaction type | N/A | PTMCode2 |
CARD16 | PYCARD | 25361965 | interaction type | N/A | PTMCode2 |
MEFV | PYCARD | 25361965 | interaction type | N/A | PTMCode2 |
PYCARD | MEFV | 25361965 | interaction type | N/A | PTMCode2 |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
EXOC5 | PYCARD | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
AIM2 | PYCARD | 19158675 19158676 22286270 24234451 24237704 24630722 25348397 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,electron microscopy,fluorescence polarization spectroscopy,molecular sieving,pull down,physical interaction | ComPPI,IntAct |
PAK1 | PYCARD | 24234451 25348397 25402006 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
SYK | PYCARD | 24234451 25348397 25605870 | phosphorylation reaction,association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,protein kinase assay | ComPPI,IntAct |
IL6ST | PYCARD | 24234451 24407287 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
SRF | PYCARD | 10847592 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
TMPRSS15 | PYCARD | 24234451 24407287 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PRKAR1A | PYCARD | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
CASP1 | PYCARD | 11967258 12019269 12191486 14525934 24234451 24630722 25348397 25605870 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,electron microscopy,experimental interaction detection,fluorescence polarization spectroscopy,pull down,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
LEMD3 | PYCARD | 24234451 24407287 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CASP8 | PYCARD | 22267217 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
IKBKB | PYCARD | 12486103 24234451 25348397 | colocalization,association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,confocal microscopy | ComPPI,IntAct |
BMPR2 | PYCARD | 24234451 24407287 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
SQSTM1 | PYCARD | 22286270 24234451 25348397 | colocalization,association | anti bait coimmunoprecipitation,physical interaction,confocal microscopy | ComPPI,IntAct |
RALB | PYCARD | 22286270 24234451 25348397 | colocalization | physical interaction,confocal microscopy | ComPPI,IntAct |
CUL2 | PYCARD | 25348397 | N/A | physical interaction | ComPPI |
PSTPIP1 | PYCARD | 24234451 24407287 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CHUK | PYCARD | 12486103 24234451 25348397 | colocalization,association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,confocal microscopy | ComPPI,IntAct |
RIPK1 | PYCARD | 24234451 25348397 25402006 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
LIG3 | PYCARD | 24234451 24407287 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PYCARD | MEFV | 11498534 12054656 12646168 14525934 17964261 24234451 25006247 25348397 | colocalization,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,imaging technique,in vivo,two hybrid | ComPPI,HPRD,IntAct |
PYCARD | NLRP3 | 11786556 14525934 15020601 19158675 24234451 24630722 25348397 | colocalization,physical association | anti tag coimmunoprecipitation,two hybrid,electron microscopy,experimental interaction detection,fluorescence polarization spectroscopy,physical interaction,fluorescence microscopy,in vitro | ComPPI,HPRD,IntAct |
PYCARD | NLRC4 | 11374873 12646168 14525934 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
PYCARD | NLRP12 | 12019269 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
PYCARD | NLRP1 | 14525934 17418785 24234451 25348397 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,in vivo | ComPPI,HPRD,IntAct |
PYCARD | PYDC2 | 14525934 17178784 17339483 24234451 25348397 | colocalization,physical association | anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,in vitro,in vivo,confocal microscopy | ComPPI,HPRD,IntAct |
PYCARD | POP1 | 14525934 17178784 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
PYCARD | NLRP2 | 25348397 | N/A | physical interaction | ComPPI |
PYCARD | BECN1 | 22286270 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PYCARD | DNAJC28 | 24234451 24407287 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PYCARD | FAM184A | 24234451 24407287 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PYCARD | PML | 24234451 24407287 25348397 27898060 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct,OmniPath |
PYCARD | INPP4B | 24234451 24407287 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PYCARD | CEP131 | 24234451 24407287 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PYCARD | ARMC2 | 24234451 24407287 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PYCARD | MYO1C | 24234451 24407287 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PYCARD | MCM4 | 24234451 24407287 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PYCARD | TSHZ2 | 24234451 24407287 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PYCARD | NUP107 | 24234451 24407287 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PYCARD | FSTL5 | 24234451 24407287 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PYCARD | NAA15 | 24234451 24407287 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PYCARD | DRC7 | 24234451 24407287 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PYCARD | TPM4 | 24234451 24407287 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PYCARD | IFI16 | 25348397 | N/A | physical interaction | ComPPI |
PYCARD | BRCA1 | 25348397 | N/A | physical interaction | ComPPI |
PYCARD | USP50 | 25348397 | N/A | physical interaction | ComPPI |
PYCARD | CDK15 | 25348397 | N/A | physical interaction | ComPPI |
PYCARD | ZYG11B | 25348397 | N/A | physical interaction | ComPPI |
PYCARD | PIGP | 25348397 | N/A | physical interaction | ComPPI |
PYCARD | BIRC5 | 25348397 | N/A | physical interaction | ComPPI |
PYCARD | FCF1 | 25348397 | N/A | physical interaction | ComPPI |
PYCARD | DDX58 | 25348397 | N/A | anti bait coimmunoprecipitation,physical interaction | ComPPI |
PYCARD | MALT1 | 22267217 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
PYCARD | CARD9 | 22267217 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
PYCARD | LAMP1 | 22286270 24234451 25348397 | colocalization | confocal microscopy | ComPPI,IntAct |
PYCARD | BAX | 14730312 24234451 25348397 | physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,confocal microscopy | ComPPI,IntAct |
PYCARD | IKBKG | 12486103 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
PYCARD | PYDC1 | 17178784 24234451 25348397 | colocalization,physical association | anti tag coimmunoprecipitation,confocal microscopy | ComPPI,IntAct |
PYCARD | ERVK-19 | 24234451 24407287 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
PYCARD | NLRC3 | 24234451 25277106 25348397 | colocalization,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,confocal microscopy | ComPPI,IntAct |
BCL10 | PYCARD | 22267217 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
ARIH2 | PYCARD | 25348397 | N/A | physical interaction | ComPPI |
PYCARD | PYCARD | 24234451 24630722 25006247 25416956 | physical association | anti tag coimmunoprecipitation,electron microscopy,fluorescence polarization spectroscopy,molecular sieving,pull down,two hybrid array | IntAct |
CASP1 | PYCARD | 11051551 11432859 11536016 11967258 12019269 12191486 14634131 15383541 16585594 19337385 21385879 24630722 24803432 27898060 | inhibition | N/A | OmniPath |
PYCARD | CASP1 | 11967258 12019269 12191486 14634131 16585594 19337385 21385879 24630722 24803432 27898060 | stimulant | N/A | OmniPath |
CHUK | PYCARD | 12486103 27898060 | N/A | N/A | OmniPath |
PYCARD | CHUK | 12486103 27898060 | N/A | N/A | OmniPath |
NLRP1 | PYCARD | 11250163 12191486 17349957 17382568 17418785 19066616 19401709 21252346 27898060 | N/A | N/A | OmniPath |
PYCARD | RIPK2 | 14634131 27898060 | N/A | N/A | OmniPath |
NLRP3 | PYCARD | 11250163 11786556 12615073 15020601 15030775 16037825 16407888 17382568 17470531 19158675 19337385 21575908 21994322 22361007 23066025 24630722 24803432 25686105 27898060 | N/A | N/A | OmniPath |
PYCARD | NLRP3 | 11250163 11786556 12615073 15020601 15030775 16037825 16407888 17382568 17470531 19158675 19337385 21575908 21994322 22361007 23066025 24630722 24803432 25686105 27898060 | N/A | N/A | OmniPath |
COP1 | PYCARD | 11051551 11432859 11536016 15383541 27898060 | inhibition | N/A | OmniPath |
TP53 | PYCARD | 18431400 27898060 | stimulant | N/A | OmniPath |
PYCARD | DDX58 | 19915568 23592984 27898060 | N/A | N/A | OmniPath |
CARD18 | PYCARD | 11051551 11432859 11536016 15383541 27898060 | inhibition | N/A | OmniPath |
PYCARD | BAX | 14730312 16964285 17464323 19062087 19968986 27898060 | stimulant | N/A | OmniPath |
NLRC4 | PYCARD | 11374873 11390368 11967258 12646168 14634131 15701651 17382568 17470531 17696608 19337385 24803432 27898060 | N/A | N/A | OmniPath |
PYCARD | NLRC4 | 11374873 11390368 11967258 12646168 14634131 15701651 17382568 17470531 17696608 19337385 24803432 27898060 | N/A | N/A | OmniPath |
PYCARD | IKBKB | 12486103 27898060 | N/A | N/A | OmniPath |
PYCARD | AIM2 | 19158675 19158676 21575908 22869553 24237704 24630722 27898060 | N/A | N/A | OmniPath |
PYCARD | IFI16 | 21575908 27898060 | N/A | N/A | OmniPath |
NLRP10 | PYCARD | 15096476 20393137 27898060 | N/A | N/A | OmniPath |
PYCARD | PYDC1 | 12656673 17178784 18362139 19337385 27898060 | N/A | N/A | OmniPath |
MEFV | PYCARD | 11498534 12054656 12646168 14595024 16037825 17431422 17964261 27898060 | inhibition | N/A | OmniPath |
PYCARD | MEFV | 11498534 12054656 12646168 14595024 16037825 17431422 17964261 27898060 | N/A | N/A | OmniPath |
NLRP2 | PYCARD | 15030775 15456791 17382568 23625868 27898060 | N/A | N/A | OmniPath |
CARD17 | PYCARD | 11051551 11432859 11536016 15383541 27898060 | inhibition | N/A | OmniPath |