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GENE：RIPK1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RIPK1
FullNmae receptor interacting serine/threonine kinase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10019
EnsembleID ENSG00000137275
Uniprot Q13546

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RIPK1 necroptosis 40007541 Necroptosis is a programmed form of cell death. Receptor-interacting serine/threonine protein kinase l (RIPK1) is a crucial protein kinase that regulates the necroptosis pathway. retulator signature
RIPK1 necroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
RIPK1 cuproptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RIPK1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RIPK1 apoptosis 38743492 We further demonstrated that RIPK1 kinase induces both caspase-8-mediated apoptosis and cell death-independent inflammation. retulator signature
RIPK1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
RIPK1 GO:0000165,GO:0001934,GO:0004672,GO:0004672,GO:0004674,GO:0004674,GO:0004674,GO:0004706,GO:0005123,GO:0005515,GO:0005524,GO:0005739,GO:0005829,GO:0005886,GO:0006915,GO:0006954,GO:0006979,GO:0010008,GO:0010628,GO:0030163,GO:0031264,GO:0031625,GO:0032757,GO:0032760,GO:0032991,GO:0033209,GO:0034612,GO:0035556,GO:0036289,GO:0036289,GO:0042802,GO:0042803,GO:0043065,GO:0043065,GO:0043066,GO:0043068,GO:0043123,GO:0043123,GO:0043124,GO:0043235,GO:0043525,GO:0044877,GO:0045651,GO:0045944,GO:0046330,GO:0046777,GO:0046777,GO:0050729,GO:0051092,GO:0060545,GO:0060546,GO:0062100,GO:0070105,GO:0070231,GO:0070266,GO:0070266,GO:0070266,GO:0070301,GO:0070513,GO:0070926,GO:0071356,GO:0071363,GO:0097191,GO:0097191,GO:0097300,GO:0097342,GO:0097343,GO:0097527,GO:0097527,GO:0106310,GO:1901026,GO:1901224,GO:1903265,GO:1903800,GO:1990000,GO:2000379,GO:2001237,GO:2001238,GO:2001240

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RIPK1 hsa:8737 path:hsa04064 NF-kappa B signaling pathway - Homo sapiens (human)
RIPK1 hsa:8737 path:hsa04210 Apoptosis - Homo sapiens (human)
RIPK1 hsa:8737 path:hsa04217 Necroptosis - Homo sapiens (human)
RIPK1 hsa:8737 path:hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human)
RIPK1 hsa:8737 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)
RIPK1 hsa:8737 path:hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human)
RIPK1 hsa:8737 path:hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human)
RIPK1 hsa:8737 path:hsa04668 TNF signaling pathway - Homo sapiens (human)
RIPK1 hsa:8737 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)
RIPK1 hsa:8737 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
RIPK1 hsa:8737 path:hsa05131 Shigellosis - Homo sapiens (human)
RIPK1 hsa:8737 path:hsa05132 Salmonella infection - Homo sapiens (human)
RIPK1 hsa:8737 path:hsa05160 Hepatitis C - Homo sapiens (human)
RIPK1 hsa:8737 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
RIPK1 hsa:8737 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)
RIPK1 hsa:8737 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RIPK1 FADD 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11464215 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 14744430 15099563 15592525 15699106 15760909 16227629 16406523 16498403 16585540 16713974 16940415 17301840 17462996 17916596 18264787 18545270 18633355 18641653 19392652 19411070 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21183682 21232017 21411734 21826665 22421439 22427918 22955274 23010170 23069999 23073834 23170255 23180781 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24366341 24378531 24699077 24958845 26024392 26192618 26201938 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 8910423 9184224 9217161 9488730 9759866 interaction type,physical association anti tag coimmunoprecipitation,two hybrid ACSN,InnateDB
RIPK1 TNF 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 12887920 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23180781 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 26587781 26653790 26972597 28574505 8910423 9488730 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
RIPK1 TRADD 10465784 10734135 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11668179 11875494 12048245 12556535 12646658 12655147 12738796 12811837 12887920 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 16713974 17301840 17462996 17496911 17560373 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19632174 19641494 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21614932 21826665 22955274 23010170 23070005 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 26587781 26653790 26972597 28574505 28765050 8910423 8974401 9379049 9488730 9582321 interaction type N/A ACSN
TRAF2 RIPK1 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866 interaction type N/A ACSN
RIPK1 RIPK3 10521396 11003656 11274345 1134007 11583996 12215447 12702723 12724420 12887920 15592525 15760909 16469705 16498403 16940415 17462996 17603935 18570872 18621737 18641653 19037093 19131965 19498109 19524512 19524513 19597341 19632174 19838173 19935698 20125124 20531300 20823910 20861672 21133840 21232017 22265414 22421439 22427918 23010170 23069999 23073834 23377657 23627914 24366341 26024392 26192618 26587781 26653790 26807733 26853145 26900751 26972597 27558815 27833036 27959630 27984721 28498367 28574505 28645028 9217161 9488730 9759866 interaction type N/A ACSN
RIPK1 GLUD1 11274345 16469705 17603935 18641653 19037093 19498109 19524512 19524513 19632174 20823910 20861672 21133840 21232017 22265414 22421439 23010170 23073834 23627914 24366341 26024392 26192618 26587781 26653790 26807733 26853145 26900751 27558815 27833036 27959630 28498367 28574505 28645028 interaction type N/A ACSN
RIPK1 GLUL 11274345 16469705 17603935 18641653 19037093 19498109 19524512 19524513 19632174 20823910 20861672 21133840 21232017 22265414 22421439 23010170 23073834 23627914 24366341 26024392 26192618 26587781 26653790 26807733 26853145 26900751 27558815 27833036 27959630 28498367 28574505 28645028 interaction type N/A ACSN
RIPK1 MLKL 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16469705 16498403 16940415 17462996 17603935 18641653 19037093 19498109 19524512 19524513 19597341 19632174 19838173 20531300 20823910 20861672 21133840 21232017 22265414 22421439 22427918 23010170 23069999 23073834 23377657 23627914 24366341 26024392 26192618 26587781 26653790 26807733 26853145 26900751 26972597 27558815 27833036 27959630 27984721 28498367 28574505 28645028 9217161 9488730 9759866 interaction type N/A ACSN
RIPK1 PGAM5 11274345 16469705 17603935 18641653 19037093 19498109 19524512 19524513 19632174 20823910 20861672 21133840 21232017 22265414 22421439 23010170 23073834 23627914 24366341 26024392 26192618 26587781 26653790 26807733 26853145 26900751 27558815 27833036 27959630 28498367 28574505 28645028 interaction type N/A ACSN
RIPK1 PYGL 11274345 16469705 17603935 18641653 19037093 19498109 19524512 19524513 19632174 20823910 20861672 21133840 21232017 22265414 22421439 23010170 23073834 23627914 24366341 26024392 26192618 26587781 26653790 26807733 26853145 26900751 27558815 27833036 27959630 28498367 28574505 28645028 interaction type N/A ACSN
RIPK1 DAXX 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26192618 26587781 26653790 26972597 27984721 28574505 9184224 9488730 9759866 interaction type N/A ACSN
RIPK1 FAF1 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26192618 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866 interaction type N/A ACSN
RIPK1 FASLG 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26192618 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866 interaction type N/A ACSN
RIPK1 FAS 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26192618 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866 interaction type N/A ACSN
RIPK1 CFLAR 11002417 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17047155 17462996 18641653 19392652 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23180781 23377657 23850759 24366341 24378531 26024392 26192618 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9488730 9759866 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
RIPK1 TNFRSF1A 10465784 11274345 11668179 12048245 12556535 12655147 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23070005 23850759 24378531 26192618 26587781 26653790 28574505 28765050 9379049 9582321 interaction type N/A ACSN
RIPK1 MAP3K1 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26192618 26587781 26653790 28574505 28765050 9379049 9582321 interaction type N/A ACSN
RIPK1 MAP3K5 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26192618 26587781 26653790 28574505 28765050 interaction type N/A ACSN
RIPK1 IKBKG 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 26587781 26653790 26972597 28574505 8910423 9488730 interaction type N/A ACSN
RIPK1 MAP3K7 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18570872 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23180781 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 26587781 26653790 26972597 28574505 8910423 9488730 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
RIPK1 TAB2 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15327770 15592525 15699106 16603398 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23180781 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 26587781 26653790 26972597 28574505 8910423 9488730 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
RIPK1 TAB3 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26192618 26201938 26587781 26653790 26972597 28574505 8910423 9488730 interaction type N/A ACSN
HTRA2 RIPK1 10521396 11583623 11803371 12815069 12835328 15781261 19935698 20125124 23070005 26192618 interaction type N/A ACSN
RIPK1 DAB2IP 11274345 15310755 17389591 18641653 19498109 19524512 19524513 19632174 21133840 21232017 23010170 23180781 26192618 26587781 26653790 28574505 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
CYLD RIPK1 19131965 23010170 26192618 interaction type N/A ACSN
ITCH RIPK1 10940313 11318614 16469705 16861923 18552861 18628966 19131965 20068034 21107885 21383157 26192618 interaction type N/A ACSN
RNF11 RIPK1 19131965 23010170 26192618 interaction type N/A ACSN
TAX1BP1 RIPK1 17703191 18239685 18246070 19131965 23010170 23180781 26192618 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
TNFAIP3 RIPK1 19131965 20599425 26192618 interaction type N/A ACSN
PTPN13 RIPK1 12702723 12724420 16498403 23069999 26192618 9184224 interaction type N/A ACSN
FAIM RIPK1 12702723 16498403 17942717 23069999 26192618 9184224 interaction type N/A ACSN
SQSTM1 RIPK1 10356400 12702723 15340068 16252010 16498403 20531300 21981924 23069999 23180781 25002027 26192618 26587781 28574505 9184224 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
SOCS1 RIPK1 10485906 12193701 12223527 12811837 21469115 23124025 26192618 interaction type N/A ACSN
STAT1 RIPK1 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 26192618 6357187 7594497 8683106 8871614 interaction type N/A ACSN
RIPK1 MAP2K4 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26192618 26587781 26653790 28574505 28765050 interaction type N/A ACSN
RIPK1 MAP2K3 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26192618 26587781 26653790 28574505 28765050 interaction type N/A ACSN
RIPK1 MAP2K7 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26192618 26587781 26653790 28574505 28765050 interaction type N/A ACSN
RIPK1 MAP2K6 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26192618 26587781 26653790 28574505 28765050 interaction type N/A ACSN
RIPK1 SQSTM1 10356400 19850933 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation InnateDB
RIPK1 PRKCI 10356400 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK1 PRKCZ 10356400 23180781 physical association anti tag coimmunoprecipitation InnateDB
RBCK1 RIPK1 17449468 23180781 physical association anti tag coimmunoprecipitation InnateDB
TNFRSF1A RIPK1 10356400 10795740 12721308 15115707 15357952 23180781 23815148 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
TICAM1 RIPK1 15814722 16281057 17982077 18450748 19734906 20200155 23180781 physical association anti tag coimmunoprecipitation,fluorescent resonance energy transfer InnateDB
RIPK1 CASP8 11002417 17047155 18570872 21419663 22421964 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK1 CASP10 11002417 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK1 TRPC4AP 14585990 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
MAVS RIPK1 18207245 21419663 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF7 RIPK1 17296724 23180781 physical association anti tag coimmunoprecipitation InnateDB
CARD6 RIPK1 16418290 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK1 TNFAIP3 15258597 17703191 18246070 23180781 deubiquitination reaction,ubiquitination reaction,physical association anti tag coimmunoprecipitation,enzymatic study InnateDB
TRADD RIPK1 16603398 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK1 CCDC50 18029035 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK1 MAP3K3 14585994 15047705 15572679 23180781 physical association anti tag coimmunoprecipitation InnateDB
OPTN RIPK1 17702576 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
MAP3K14 RIPK1 15047705 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK1 BIRC2 15147886 18570872 23180781 ubiquitination reaction,physical association anti tag coimmunoprecipitation,enzymatic study InnateDB
RIPK1 UBE2D1 15147886 23180781 ubiquitination reaction enzymatic study InnateDB
RIPK1 BIRC3 15147886 18570872 23180781 ubiquitination reaction,physical association anti tag coimmunoprecipitation,enzymatic study InnateDB
TNF RIPK1 12887920 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK1 ITCH 18246070 23180781 physical association anti tag coimmunoprecipitation InnateDB
UBE2N RIPK1 18570872 19734906 23180781 ubiquitination reaction enzymatic study InnateDB
RIPK1 ZBP1 18941233 19590578 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK1 TRAF2 10795740 11479302 16603398 23180781 physical association anti tag coimmunoprecipitation InnateDB
PELI1 RIPK1 19734906 23180781 physical association anti tag coimmunoprecipitation InnateDB
CHUK RIPK1 18949366 23180781 24323043 physical association affinity chromatography technology,anti tag coimmunoprecipitation InnateDB
IKBKB RIPK1 18362886 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK1 TANK 21419663 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK1 ANXA1 21383699 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK3 RIPK1 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
CASP8 RIPK1 22421964 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKG RIPK1 14653779 16547522 16603398 17702576 23180781 9927690 physical association anti tag coimmunoprecipitation,gst pull down,pull down InnateDB
RIPK1 RIPK1 11369754 12887920 15327770 16603398 18545270 19927120 20404851 21525013 26467481 phosphorylation reaction,bind,up-regulates,up-regulates activity N/A Signor

Source Target Pmid Interactiontype Methods Database
FADD RIPK1 11854271 20005715 21071413 21737329 interaction type N/A PSP,SignaLink
PIDD1 RIPK1 20005715 interaction type N/A PSP,SignaLink
SQSTM1 RIPK1 20005715 interaction type N/A PSP
TICAM1 RIPK1 20005715 interaction type N/A PSP
TRADD RIPK1 18988627 20005715 21071413 8612133 interaction type N/A PSP,SignaLink
TRAF1 RIPK1 20005715 interaction type N/A PSP
TRAF2 RIPK1 20005715 21071413 21282461 8612133 9020361 interaction type N/A PSP,SignaLink
TRAF3 RIPK1 20005715 interaction type N/A PSP
TRAF5 RIPK1 20005715 interaction type N/A PSP
SQSTM1 RIPK1 10356400 20005715 20005715 21071413 N/A N/A SignaLink
TICAM1 RIPK1 15064760 19734906 20005715 20005715 21071413 N/A N/A SignaLink
TRAF1 RIPK1 20005715 20005715 N/A N/A SignaLink
TRAF3 RIPK1 20005715 20005715 N/A N/A SignaLink
TRAF5 RIPK1 11479302 20005715 20005715 21071413 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ESR1 RIPK1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 RIPK1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 RIPK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RIPK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RIPK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 RIPK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RIPK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RIPK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RIPK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RIPK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 RIPK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 RIPK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 RIPK1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
RIPK1 RIPK1 22135298 phosphorylation N/A PhosphoSite
RIPK1 DAB2IP 22135298 phosphorylation N/A PhosphoSite
TICAM1 RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 TICAM1 25361965 interaction type N/A PTMCode2
TNFAIP3 RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 TNFAIP3 25361965 interaction type N/A PTMCode2
RIPK3 RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 RIPK3 25361965 interaction type N/A PTMCode2
RIPK1 TRAF5 25361965 interaction type N/A PTMCode2
TRAF5 RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 MAP3K8 25361965 interaction type N/A PTMCode2
MAP3K8 RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 BIRC3 25361965 interaction type N/A PTMCode2
BIRC3 RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 CASP10 25361965 interaction type N/A PTMCode2
CASP10 RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 FADD 25361965 interaction type N/A PTMCode2
FADD RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 CYLD 25361965 interaction type N/A PTMCode2
CYLD RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 CFLAR 25361965 interaction type N/A PTMCode2
CFLAR RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 TRAF3 25361965 interaction type N/A PTMCode2
TRAF3 RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 HSP90AA1 25361965 interaction type N/A PTMCode2
HSP90AA1 RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 PIDD1 25361965 interaction type N/A PTMCode2
PIDD1 RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 TRADD 25361965 interaction type N/A PTMCode2
TRADD RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 CASP8 25361965 interaction type N/A PTMCode2
CASP8 RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 MAP3K3 25361965 interaction type N/A PTMCode2
MAP3K3 RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 IKBKG 25361965 interaction type N/A PTMCode2
IKBKG RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 RNF216 25361965 interaction type N/A PTMCode2
RNF216 RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 CCDC50 25361965 interaction type N/A PTMCode2
CCDC50 RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 TNF 25361965 interaction type N/A PTMCode2
TNF RIPK1 25361965 interaction type N/A PTMCode2
NFKB1 RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 NFKB1 25361965 interaction type N/A PTMCode2
TNFRSF10A RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 TNFRSF10A 25361965 interaction type N/A PTMCode2
TNFRSF1A RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 TNFRSF1A 25361965 interaction type N/A PTMCode2
BIRC2 RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 BIRC2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
DAXX RIPK1 23260419 24234451 25348397 N/A pull down ComPPI,IntAct
TRIM38 RIPK1 11854271 14525934 24234451 25348397 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD,IntAct
HSPA8 RIPK1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
GPX7 RIPK1 25348397 N/A physical interaction ComPPI
ANXA1 RIPK1 21383699 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,molecular sieving,physical interaction,confocal microscopy ComPPI,IntAct
TNFAIP3 RIPK1 14525934 15258597 24234451 25348397 30561431 association experimental interaction detection,physical interaction,in vitro,in vivo,virotrap ComPPI,HPRD,IntAct
ACTG1 RIPK1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TUBB RIPK1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
XIAP RIPK1 21931591 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
OPTN RIPK1 25348397 N/A physical interaction ComPPI
HSP90AB1 RIPK1 14743216 22939624 24234451 25348397 physical association tandem affinity purification,luminescence based mammalian interactome mapping ComPPI,IntAct
EGLN3 RIPK1 25348397 N/A physical interaction ComPPI
KHDRBS1 RIPK1 25348397 N/A physical interaction ComPPI
UBB RIPK1 25348397 N/A anti bait coimmunoprecipitation,physical interaction,comigration in sds page ComPPI
UBC RIPK1 17053834 17981138 18621737 21765415 22037414 25348397 25423073 25715336 26017671 27898060 N/A anti bait coimmunoprecipitation,physical interaction,comigration in sds page ComPPI,OmniPath
RPS27A RIPK1 25348397 N/A anti bait coimmunoprecipitation,physical interaction,comigration in sds page ComPPI
UBA52 RIPK1 25348397 N/A anti bait coimmunoprecipitation,physical interaction,comigration in sds page ComPPI
HSP90AA1 RIPK1 10744744 14525934 14743216 24234451 25348397 physical association experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
UBE2N RIPK1 25348397 N/A physical interaction ComPPI
AP1M2 RIPK1 25348397 N/A physical interaction ComPPI
HSPA5 RIPK1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CASP8 RIPK1 10521396 11002417 12215447 12884866 12887920 14525934 17047155 18485876 19060883 19524512 19524513 21458669 21525013 22173242 22274400 23955153 24234451 25348397 25911380 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
IKBKB RIPK1 25348397 N/A physical interaction ComPPI
TRAF3 RIPK1 14525934 24234451 25348397 8612133 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid array,in vivo,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
TNFRSF1A RIPK1 14525934 16611992 18022363 19524513 19781631 22817896 24234451 25348397 8612133 association,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
TNFRSF25 RIPK1 25348397 N/A physical interaction ComPPI
CAD RIPK1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
SQSTM1 RIPK1 10356400 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
FADD RIPK1 11002422 14525934 19524513 21458669 21525013 24234451 25348397 30561431 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid array,in vivo,two hybrid prey pooling approach,virotrap ComPPI,HPRD,IntAct
TNF RIPK1 12887920 22028622 23104095 23815148 23955153 24234451 25348397 25911380 association anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification ComPPI,IntAct
XPO1 RIPK1 25348397 N/A physical interaction ComPPI
USP4 RIPK1 21331078 23313255 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
TRAF1 RIPK1 14525934 24234451 25348397 25416956 8612133 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
TRAF2 RIPK1 14525934 16291755 21810480 24234451 25348397 25416956 30561431 8612133 8702708 association,physical association anti bait coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid array,in vivo,two hybrid prey pooling approach,validated two hybrid,two hybrid,virotrap ComPPI,HPRD,IntAct
EGFR RIPK1 11116146 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TRAF5 RIPK1 11479302 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ITCH RIPK1 14525934 19131965 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CHUK RIPK1 25348397 N/A physical interaction ComPPI
TAX1BP1 RIPK1 14525934 19131965 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
HSPA9 RIPK1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CASP10 RIPK1 12884866 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
RIPK1 MAP3K3 11429546 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RIPK1 CRADD 14525934 25348397 8985253 9044836 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RIPK1 TRADD 14525934 24234451 25348397 30561431 8612133 association,physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,virotrap ComPPI,HPRD,IntAct
RIPK1 TNFRSF10A 14525934 25348397 9430227 N/A experimental interaction detection,in vivo ComPPI,HPRD
RIPK1 TNFRSF10B 14525934 25348397 9430227 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RIPK1 TRPC4AP 14525934 14585990 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RIPK1 RIPK3 10339433 14525934 19524512 19524513 22265413 22265414 22817896 24234451 25348397 26559832 phosphorylation reaction,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,circular dichroism,two hybrid,electron microscopy,experimental interaction detection,fluorescence technology,molecular sieving,pull down,physical interaction,protein kinase assay,in vivo,comigration in sds page,solid state nmr,two hybrid ComPPI,HPRD,IntAct
RIPK1 RNF216 11854271 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
RIPK1 ZFAND5 14525934 14754897 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RIPK1 TICAM1 14525934 15064760 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RIPK1 NFKB1 14525934 16291755 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RIPK1 MAP3K8 14525934 16291755 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RIPK1 CCDC50 14525934 18029035 1802935 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
RIPK1 RNF11 14525934 19131965 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RIPK1 FAS 14525934 24234451 25348397 7538908 9740801 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
RIPK1 IKBKG 10755617 10880512 10980203 14525934 14653779 21383699 21458669 23104095 24234451 25348397 30561431 association,physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid,virotrap ComPPI,HPRD,IntAct
RIPK1 BIRC2 21931591 24234451 25348397 30561431 ubiquitination reaction,association,physical association anti tag coimmunoprecipitation,pull down,physical interaction,enzymatic study,virotrap ComPPI,IntAct
RIPK1 BIRC3 21931591 24234451 25348397 ubiquitination reaction,physical association anti tag coimmunoprecipitation,pull down,physical interaction,enzymatic study ComPPI,IntAct
RIPK1 MAP3K7 25348397 N/A physical interaction ComPPI
RIPK1 TAB2 25348397 N/A physical interaction ComPPI
RIPK1 CYLD 25348397 N/A physical interaction ComPPI
RIPK1 HSP90AA2P 25348397 N/A physical interaction ComPPI
RIPK1 PIDD1 17159900 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RIPK1 CDC42BPB 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
RIPK1 USP21 25348397 N/A physical interaction ComPPI
RIPK1 USP2 25348397 N/A physical interaction ComPPI
RIPK1 NOD2 25348397 N/A physical interaction ComPPI
RIPK1 RIPK2 25348397 N/A physical interaction ComPPI
RIPK1 RBCK1 25348397 N/A physical interaction ComPPI
RIPK1 TLR3 25348397 N/A physical interaction ComPPI
RIPK1 CLIP3 25348397 N/A physical interaction ComPPI
RIPK1 DAB2IP 25348397 N/A physical interaction ComPPI
RIPK1 TNFRSF1B 25348397 N/A physical interaction ComPPI
RIPK1 LRRK2 19176810 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RIPK1 TNFSF10 25348397 N/A physical interaction ComPPI
RIPK1 NUMBL 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RIPK1 YOD1 25348397 N/A physical interaction ComPPI
RIPK1 OTUD1 25348397 N/A physical interaction ComPPI
RIPK1 RFFL 25348397 N/A physical interaction ComPPI
RIPK1 PYCARD 24234451 25348397 25402006 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RIPK1 MLF1 25348397 N/A physical interaction ComPPI
RIPK1 NTAN1 25348397 N/A physical interaction ComPPI
RIPK1 FGL1 25348397 N/A physical interaction ComPPI
RIPK1 HERC2 25348397 N/A physical interaction ComPPI
RIPK1 HERC2P3 25348397 N/A physical interaction ComPPI
RIPK1 RNF31 25348397 N/A physical interaction ComPPI
RIPK1 ERN1 25348397 N/A physical interaction ComPPI
RIPK1 TRIM27 25348397 N/A physical interaction ComPPI
RIPK1 MLKL 25348397 N/A physical interaction ComPPI
RIPK1 ATG7 25348397 N/A physical interaction ComPPI
RIPK1 THSD4 25348397 N/A physical interaction ComPPI
RIPK1 XAF1 25348397 N/A physical interaction ComPPI
RIPK1 CARD6 16418290 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RIPK1 HSPA1L 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK1 SLC25A5 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK1 DNAJA1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK1 TIMM50 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK1 RCN2 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK1 TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK1 TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK1 CSNK1A1 18067272 24234451 25348397 phosphorylation reaction,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,protein kinase assay ComPPI,IntAct
RIPK1 PGAM5 25348397 N/A anti tag coimmunoprecipitation ComPPI
RIPK1 ZBP1 22817896 24234451 25348397 N/A electron microscopy ComPPI,IntAct
RIPK1 LTA 23815148 24234451 25348397 association tandem affinity purification ComPPI,IntAct
RIPK1 CDC37 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
MAP3K14 RIPK1 11116146 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CFLAR RIPK1 10837247 14525934 17047155 24234451 25348397 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
RPL23 RIPK1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PELI1 RIPK1 25348397 N/A physical interaction ComPPI
HSCB RIPK1 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
RIPK1 RIPK1 14525934 14743216 15175328 22817896 23473668 24234451 25416956 phosphorylation reaction,physical association circular dichroism,electron microscopy,experimental interaction detection,fluorescence technology,molecular sieving,two hybrid array,protein kinase assay,tandem affinity purification,two hybrid prey pooling approach HPRD,IntAct
TNIP2 RIPK1 24234451 30561431 association virotrap IntAct
RIPK1 BCS1L 22017868 27898060 N/A N/A OmniPath
ANXA1 RIPK1 21383699 27898060 N/A N/A OmniPath
RIPK1 ANXA1 21383699 27898060 N/A N/A OmniPath
RIPK1 ITCH 18246070 19131965 27898060 N/A N/A OmniPath
RIPK1 MAP3K7 16543241 18570872 21606198 24434549 27898060 stimulant N/A OmniPath
TNFAIP3 RIPK1 15258597 17703191 18239685 18246070 18570872 18621737 19131965 21765415 22585859 23602765 27898060 inhibition N/A OmniPath
RIPK1 TNFAIP3 15258597 17703191 18239685 18246070 18570872 18621737 19131965 21765415 22585859 23602765 27898060 N/A N/A OmniPath
CHUK RIPK1 18949366 24323043 27898060 N/A N/A OmniPath
TRAF2 RIPK1 10795740 11181075 11479302 12441346 15258597 16291755 16603398 18621737 18981220 19815541 20577214 21232017 21282461 21810480 23007157 23972990 24434549 24735611 25416956 25716317 27898060 8612133 8702708 9020361 9712898 stimulant N/A OmniPath
RIPK1 TRAF2 10795740 11181075 11479302 12441346 16291755 16603398 19815541 20577214 21232017 21282461 21810480 23007157 23972990 24434549 24735611 25416956 25716317 27898060 8612133 8702708 9020361 stimulant N/A OmniPath
TICAM1 RIPK1 14739303 15064760 15814722 16281057 16410796 17982077 18450748 19734906 20200155 20404851 25736436 27898060 stimulant N/A OmniPath
FADD RIPK1 11002422 11464215 11854271 16227629 16585540 18485876 18946037 19373245 19524513 21052097 21183682 21458669 21525013 21620750 21737329 22037414 22848449 22864571 22890322 22922561 23972990 24577083 26186194 26865630 27898060 stimulant N/A OmniPath
RIPK1 FADD 11002422 11464215 11854271 16227629 16585540 18485876 18946037 19373245 19524513 21052097 21183682 21458669 21620750 21737329 22037414 22848449 22864571 22922561 23972990 24577083 26186194 26865630 27898060 stimulant N/A OmniPath
RIPK1 MAP3K14 11116146 15047705 27898060 stimulant N/A OmniPath
RIPK3 RIPK1 10339433 11734559 19524512 19524513 21903422 22265413 22265414 22817896 22864571 27898060 stimulant N/A OmniPath
RIPK1 MAP3K1 11369754 27898060 stimulant N/A OmniPath
CRADD RIPK1 27898060 8985253 9044836 stimulant N/A OmniPath
RIPK1 TRAF6 20404851 27898060 inhibition,stimulant N/A OmniPath
TNFRSF10B RIPK1 22585859 27898060 9430227 stimulant N/A OmniPath
PIDD1 RIPK1 16360037 17159900 27898060 stimulant N/A OmniPath
MAVS RIPK1 18207245 21419663 27898060 N/A N/A OmniPath
RIPK1 IKBKG 10755617 10880512 10980203 11262391 14653779 16543241 16547522 16603398 16965765 17702576 17981138 18029035 18212736 19373245 21113135 21383699 21458669 21606198 22037414 22099304 23746843 24735611 26740240 26802121 26865630 27898060 9927690 stimulant N/A OmniPath
IKBKG RIPK1 10755617 10880512 10980203 11262391 14653779 16543241 16547522 16603398 16965765 17702576 17981138 18029035 18212736 19373245 21113135 21383699 21458669 21606198 22037414 22099304 23746843 24735611 26740240 26802121 26865630 27898060 9927690 N/A N/A OmniPath
CASP2 RIPK1 15590671 27898060 stimulant N/A OmniPath
RIPK1 TRADD 12441346 16603398 18545270 21724995 24735611 27898060 8612133 stimulant N/A OmniPath
TRADD RIPK1 12441346 16603398 18545270 21724995 24735611 27898060 8612133 stimulant N/A OmniPath
RIPK1 CASP8 10521396 11002417 11002422 12215447 12884866 12887920 17047155 18570872 19060883 19373245 19773432 20825417 21282461 21419663 21458669 21525013 21737329 21737330 22179575 22274400 22421964 22585859 22864571 23972990 24577083 25911380 25939870 27898060 stimulant N/A OmniPath
CASP8 RIPK1 10469655 10521396 11002417 11002422 11042193 12215447 12842894 12884866 12887920 17047155 18570872 19060883 19373245 19773432 20825417 21282461 21419663 21458669 21525013 21737329 21737330 22179575 22274400 22421964 22585859 22864571 23972990 24577083 25911380 25939870 27898060 8657102 inhibition N/A OmniPath
RIPK1 CASP10 11002417 12884866 27898060 stimulant N/A OmniPath
CASP10 RIPK1 11002417 12884866 16186808 27898060 inhibition N/A OmniPath
TNF RIPK1 12753742 12887920 16603398 18621737 19955178 20005846 21331077 21620750 22099304 22675546 23032187 24469399 24726327 24980434 25911380 26670046 27898060 N/A N/A OmniPath
FAS RIPK1 18545270 27898060 7538908 9740801 stimulant N/A OmniPath
RIPK1 FAS 18545270 27898060 7538908 9740801 stimulant N/A OmniPath
RIPK1 TAB2 15327770 16603398 18299187 27898060 stimulant N/A OmniPath
TAB2 RIPK1 15327770 16603398 18299187 27898060 N/A N/A OmniPath
BIRC2 RIPK1 15147886 16603398 18570872 18621737 19284370 19854138 21113135 21931591 23972990 26612615 27898060 inhibition,stimulant N/A OmniPath
RIPK1 BIRC2 15147886 18570872 19854138 21113135 21931591 23972990 26612615 27898060 N/A N/A OmniPath
BIRC3 RIPK1 15147886 16547522 16603398 18570872 18621737 19284370 21113135 21931591 23972990 27898060 stimulant N/A OmniPath
RIPK1 BIRC3 15147886 16547522 18570872 21113135 21931591 23972990 27898060 N/A N/A OmniPath
IRF7 RIPK1 17296724 27898060 N/A N/A OmniPath
TNFRSF1A RIPK1 10356400 10795740 11002422 12721308 12887920 15115707 15258597 15357952 16115877 16547522 16611992 16968706 18022363 18329793 18450452 18621737 18724939 18939944 18949366 19524513 19773432 19815541 20448643 20547836 20825417 21113135 21331078 21737329 22179575 22733818 22817896 22848449 23602765 23815148 24130170 24758719 25681446 26802121 27898060 7538908 8612133 8985253 inhibition,stimulant N/A OmniPath
UBE2N RIPK1 18570872 19734906 27898060 N/A N/A OmniPath
CFLAR RIPK1 10837247 11002417 17047155 21737330 27898060 inhibition N/A OmniPath
RIPK1 CFLAR 10837247 11002417 17047155 21737330 27898060 N/A N/A OmniPath
SQSTM1 RIPK1 10356400 19850933 27898060 stimulant N/A OmniPath
MAP3K3 RIPK1 11429546 14585994 15047705 15572679 27898060 N/A N/A OmniPath
RIPK1 IKBKB 10980203 18362886 21606198 27898060 stimulant N/A OmniPath
TNFRSF10A RIPK1 27898060 9430227 stimulant N/A OmniPath
IL15 RIPK1 21903422 27898060 N/A N/A OmniPath
TANK RIPK1 21419663 27898060 N/A N/A OmniPath
RIPK1 CARD6 16418290 27898060 N/A N/A OmniPath
RIPK1 TRPC4AP 14585990 27898060 N/A N/A OmniPath
TRPC4AP RIPK1 14585990 27898060 N/A N/A OmniPath
RIPK1 DAB2IP 15310755 17389591 27858941 27898060 stimulant N/A OmniPath
OPTN RIPK1 17702576 21408173 22675546 27898060 N/A N/A OmniPath
CCDC50 RIPK1 18029035 1802935 27898060 N/A N/A OmniPath
TAX1BP1 RIPK1 17703191 18239685 18246070 18570872 18621737 19131965 27898060 N/A N/A OmniPath
RIPK1 PELI1 19734906 27898060 N/A N/A OmniPath
PELI1 RIPK1 19734906 27898060 N/A N/A OmniPath
RBCK1 RIPK1 17449468 27898060 inhibition N/A OmniPath
ZBP1 RIPK1 18941233 19590578 22817896 27898060 N/A N/A OmniPath
RIPK1 TAB3 19927120 27898060 stimulant N/A OmniPath

Visualization










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