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GENE：RIT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RIT1
FullNmae Ras like without CAAX 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10023
EnsembleID ENSG00000143622
Uniprot Q92963

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RIT1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RIT1 GO:0003924,GO:0003924,GO:0003925,GO:0005515,GO:0005516,GO:0005525,GO:0005525,GO:0005886,GO:0007165,GO:0007265,GO:0007265,GO:0019003

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RALGDS RIT1 10545207 23180781 physical association two hybrid InnateDB
RLF RIT1 10545207 23180781 physical association two hybrid,gst pull down InnateDB
AFDN RIT1 10545207 23180781 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
AR RIT1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 RIT1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 RIT1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A RIT1 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 RIT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RIT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RIT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR RIT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000007FBA RIT1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00001F0C23 RIT1 22815788 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase

Source Target Pmid Interactiontype Methods Database
KLHL12 RIT1 25361965 interaction type N/A PTMCode2
RIT1 KLHL12 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NF2 RIT1 25348397 N/A physical interaction ComPPI
GRB2 RIT1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
SMAD2 RIT1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMAD3 RIT1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CUL3 RIT1 14525934 18303015 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
AP2A1 RIT1 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
RIT1 RLF 10545207 14525934 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid ComPPI,HPRD,IntAct
RIT1 RGL1 10545207 14525934 24234451 25348397 physical association experimental interaction detection,pull down,in vitro ComPPI,HPRD,IntAct
RIT1 SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RIT1 PTN 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RIT1 LRIF1 14525934 16169070 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
RIT1 KLHL12 14525934 183031015 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
RIT1 RALGDS 10545207 14525934 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
RIT1 AFDN 10545207 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RIT1 VHL 25348397 N/A physical interaction ComPPI
RIT1 ASB4 25348397 N/A physical interaction ComPPI
RIT1 SRPK2 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
RIT1 CAMKV 25348397 N/A physical interaction ComPPI
RIT1 RIT2 25348397 N/A physical interaction ComPPI
RIT1 MAD2L1BP 25348397 N/A physical interaction ComPPI
RIT1 RIF1 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
RIT1 IFRD1 14525934 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RIT1 RGL3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RIT1 LRRK2 24234451 25348397 29513927 N/A protein array ComPPI,IntAct
LZTR1 RIT1 25348397 N/A physical interaction ComPPI
DLST RIT1 24234451 30021884 physical association cross-linking study IntAct
RALGDS RIT1 10545207 27898060 stimulant N/A OmniPath
AFDN RIT1 10545207 27898060 stimulant N/A OmniPath
RLF RIT1 10545207 27898060 stimulant N/A OmniPath

Visualization










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