GENE:RNMT
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | RNMT |
| FullNmae | RNA guanine-7 methyltransferase |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:10075 |
| EnsembleID | ENSG00000101654 |
| Uniprot | O43148 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| RNMT | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| RNMT | GO:0001650,GO:0003723,GO:0004482,GO:0004482,GO:0004482,GO:0004482,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005845,GO:0005845,GO:0006370,GO:0006370,GO:0006370,GO:0006370,GO:0031533,GO:0043235,GO:0106005,GO:1990830 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| RNMT | hsa:8731 | path:hsa03015 | mRNA surveillance pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | RNMT | 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | RNMT | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| HIF1A | RNMT | 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| CEBPA | RNMT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| JUN | RNMT | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MYC | RNMT | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| NFKB1 | RNMT | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PAX3 | RNMT | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SMAD7 | RNMT | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SP1 | RNMT | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SP3 | RNMT | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| STAT1 | RNMT | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| STAT5A | RNMT | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| STAT5B | RNMT | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000324096 | RNMT | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS00005651EE | RNMT | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001597DC | RNMT | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000000B1C9 | RNMT | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00002DD349 | RNMT | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000183BED | RNMT | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CC864 | RNMT | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000315338 | RNMT | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000259AE4 | RNMT | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000236310 | RNMT | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000018C928 | RNMT | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000085F64 | RNMT | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040EE1D | RNMT | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171CD1 | RNMT | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041CB9C | RNMT | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CC379 | RNMT | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00003D8730 | RNMT | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000046CDA6 | RNMT | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000157FBE | RNMT | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000306C70 | RNMT | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000007F792 | RNMT | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002578DA | RNMT | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C7662 | RNMT | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CDK1 | RNMT | 22135298 | phosphorylation | N/A | PhosphoSite |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| KPNA2 | RNMT | 11114884 14525934 24234451 25348397 27898060 | physical association | two hybrid,experimental interaction detection,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach | ComPPI,HPRD,IntAct,OmniPath |
| GMCL1 | RNMT | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CUL5 | RNMT | 25348397 | N/A | physical interaction | ComPPI |
| KPNA5 | RNMT | 25348397 | N/A | physical interaction | ComPPI |
| TP53BP1 | RNMT | 24234451 25348397 29656893 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| KPNA1 | RNMT | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| DCUN1D1 | RNMT | 25348397 | N/A | physical interaction | ComPPI |
| MCM2 | RNMT | 25348397 | N/A | physical interaction | ComPPI |
| RAMAC | RNMT | 24234451 25348397 30021884 | physical association | two hybrid,cross-linking study,physical interaction,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| JUN | RNMT | 24234451 25348397 25609649 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| COPS5 | RNMT | 25348397 | N/A | physical interaction | ComPPI |
| CUL3 | RNMT | 25348397 | N/A | physical interaction | ComPPI |
| NTRK1 | RNMT | 25348397 | N/A | physical interaction | ComPPI |
| CUL2 | RNMT | 25348397 | N/A | physical interaction | ComPPI |
| CUL1 | RNMT | 25348397 | N/A | physical interaction | ComPPI |
| GABARAP | RNMT | 20562859 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| MDC1 | RNMT | 24234451 25348397 29656893 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| TRPC4AP | RNMT | 25348397 | N/A | physical interaction | ComPPI |
| CAND1 | RNMT | 25348397 | N/A | physical interaction | ComPPI |
| NFATC2IP | RNMT | 25348397 | N/A | physical interaction | ComPPI |
| RNMT | RNGTT | 14525934 25348397 27898060 9705270 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD,OmniPath |
| RNMT | HECW2 | 25348397 | N/A | physical interaction | ComPPI |
| RNMT | KIF23 | 25348397 | N/A | physical interaction | ComPPI |
| RNMT | BRCA1 | 25348397 | N/A | physical interaction | ComPPI |
| RNMT | PLEKHA3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| KPNA6 | RNMT | 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
