Gene Information gene info

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GENE：SDC2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SDC2
FullNmae syndecan 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10659
EnsembleID ENSG00000169439
Uniprot P34741

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SDC2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SDC2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SDC2 GO:0005515,GO:0005788,GO:0005796,GO:0005886,GO:0005886,GO:0008150,GO:0009986,GO:0016477,GO:0030165,GO:0042802,GO:0043202,GO:0048813,GO:0048814,GO:0062023

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SDC2 hsa:6383 path:hsa04514 Cell adhesion molecules - Homo sapiens (human)
SDC2 hsa:6383 path:hsa05144 Malaria - Homo sapiens (human)
SDC2 hsa:6383 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
SDC2 hsa:6383 path:hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SDC2 CSF2 10734053 23180781 physical association ion exchange chromatography InnateDB
SDC2 CSF2RA 10734053 23180781 physical association anti tag coimmunoprecipitation InnateDB
SDC2 ELAVL1 19322201 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR SDC2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 SDC2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A SDC2 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 SDC2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 SDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 SDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 SDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 SDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000C4DB5 SDC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075D1FC SDC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000383DF4 SDC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075B0F6 SDC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004CD810 SDC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001310DE SDC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000081D1E SDC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000572E11 SDC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000028D811 SDC2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000005A8ED SDC2 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SRC SDC2 22135298 phosphorylation N/A PhosphoSite
FGF2 SDC2 25361965 interaction type N/A PTMCode2
SDC2 FGF2 25361965 interaction type N/A PTMCode2
SDC2 EZR 25361965 interaction type N/A PTMCode2
EZR SDC2 25361965 interaction type N/A PTMCode2
SDC2 TNFSF13 25361965 interaction type N/A PTMCode2
TNFSF13 SDC2 25361965 interaction type N/A PTMCode2
SDC2 SDC3 25361965 interaction type N/A PTMCode2
SDC3 SDC2 25361965 interaction type N/A PTMCode2
SDC2 SDC4 25361965 interaction type N/A PTMCode2
SDC4 SDC2 25361965 interaction type N/A PTMCode2
SDC2 EPHB2 25361965 interaction type N/A PTMCode2
EPHB2 SDC2 25361965 interaction type N/A PTMCode2
SDC2 CASK 25361965 interaction type N/A PTMCode2
CASK SDC2 25361965 interaction type N/A PTMCode2
SDC1 SDC2 25361965 interaction type N/A PTMCode2
SDC2 SDC1 25361965 interaction type N/A PTMCode2
SDCBP SDC2 25361965 interaction type N/A PTMCode2
SDC2 SDCBP 25361965 interaction type N/A PTMCode2
TGFB1 SDC2 25361965 interaction type N/A PTMCode2
SDC2 TGFB1 25361965 interaction type N/A PTMCode2
CSF2 SDC2 25361965 interaction type N/A PTMCode2
SDC2 CSF2 25361965 interaction type N/A PTMCode2
PRKCA SDC2 25361965 interaction type N/A PTMCode2
SDC2 PRKCA 25361965 interaction type N/A PTMCode2
TGFBR3 SDC2 25361965 interaction type N/A PTMCode2
SDC2 TGFBR3 25361965 interaction type N/A PTMCode2
HGF SDC2 25361965 interaction type N/A PTMCode2
SDC2 HGF 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TMEM11 SDC2 25348397 N/A physical interaction ComPPI
TGFB1 SDC2 14525934 14976204 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CSF2 SDC2 10734053 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
GPR50 SDC2 25348397 N/A physical interaction ComPPI
H2AC11 SDC2 25348397 N/A physical interaction ComPPI
S100A13 SDC2 25348397 N/A physical interaction ComPPI
REG3A SDC2 14525934 25348397 8997243 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TIAM1 SDC2 23395182 24234451 25348397 N/A classical fluorescence spectroscopy,physical interaction ComPPI,IntAct
PRKCA SDC2 14525934 25348397 9244383 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
EPHB2 SDC2 11580899 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FGFR2 SDC2 25348397 N/A physical interaction ComPPI
SERPINC1 SDC2 1315572 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
SDC2 TGFBR3 14525934 14976204 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SDC2 EZR 10704377 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SDC2 FGF2 14525934 16982797 25348397 N/A experimental interaction detection,physical interaction,enzyme linked immunosorbent assay,in vitro ComPPI,HPRD
SDC2 HGF 14525934 25348397 27898060 8157651 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
SDC2 NF1 11356864 24234451 25348397 physical association two hybrid,physical interaction,in vitro,in vivo ComPPI,IntAct
SDC2 PF4 14525934 25348397 27898060 7524669 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
SDC2 PRKCB 14525934 25348397 9244383 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SDC2 PRKCG 14525934 25348397 9244383 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SDC2 SPARC 14525934 25348397 2745554 N/A experimental interaction detection,in vitro ComPPI,HPRD
SDC2 CASK 14525934 24234451 25348397 9660868 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
SDC2 ANOS1 14525934 25348397 27898060 8832397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
SDC2 LAMA3 11373281 25348397 27898060 N/A physical interaction,in vitro,solid phase assay ComPPI,OmniPath
SDC2 SDCBP 14525934 18256285 24234451 25348397 9391086 N/A experimental interaction detection,far western blotting,physical interaction,in vitro ComPPI,HPRD,IntAct
SDC2 TRAPPC4 11018053 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
SDC2 EPB41L1 25348397 N/A physical interaction ComPPI
SDC2 ITPR1 25348397 N/A physical interaction ComPPI
SDC2 CSF2RA 25348397 N/A physical interaction ComPPI
SDC2 FN1 10772816 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SDC2 ELAVL1 25348397 N/A physical interaction ComPPI
SDC2 CYP2C18 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SDC2 BAG6 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SDC2 SERPINA1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SDC2 PPP3CC 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SDC2 EFNB2 25348397 N/A physical interaction ComPPI
SDC2 FGF1 25348397 N/A physical interaction ComPPI
SDC2 GPR183 25348397 N/A physical interaction ComPPI
SDC2 SLC18A1 25348397 N/A physical interaction ComPPI
SDC2 ATXN3 25348397 N/A physical interaction ComPPI
SDC2 POLR2F 25348397 N/A physical interaction ComPPI
SDC2 TMPO 25348397 N/A physical interaction ComPPI
SDC2 TMPO 25348397 N/A physical interaction ComPPI
SDC2 CBX4 25348397 N/A physical interaction ComPPI
SDC2 SYNCRIP 25348397 N/A physical interaction ComPPI
SDC2 DHRS2 25348397 N/A physical interaction ComPPI
SDC2 PDPK1 25348397 N/A physical interaction ComPPI
SDC2 GMEB1 25348397 N/A physical interaction ComPPI
SDC2 PRDM10 25348397 N/A physical interaction ComPPI
SDC2 GMEB2 25348397 N/A physical interaction ComPPI
SDC2 CAMKV 25348397 N/A physical interaction ComPPI
SDC2 SNX33 25348397 N/A physical interaction ComPPI
SDC2 SULF1 25348397 N/A physical interaction ComPPI
SDC2 TEFM 25348397 N/A physical interaction ComPPI
SDC2 NBEAL1 25348397 N/A physical interaction ComPPI
SDC2 PARP2 25348397 N/A physical interaction ComPPI
SDC2 DOP1B 25348397 N/A physical interaction ComPPI
SDC2 SEMA3C 25348397 N/A physical interaction ComPPI
SDC2 FARP1 25348397 N/A physical interaction ComPPI
SDC2 AMPD2 25348397 N/A physical interaction ComPPI
SDC2 TMEM192 25348397 N/A physical interaction ComPPI
SDC2 KLHL7 25348397 N/A physical interaction ComPPI
SDC2 SNX18 25348397 N/A physical interaction ComPPI
SDC2 GTF3C2 25348397 N/A physical interaction ComPPI
SDC2 VANGL1 25348397 N/A physical interaction ComPPI
SDC2 FGFRL1 25348397 N/A physical interaction ComPPI
SDC2 FGFR3 25348397 N/A physical interaction ComPPI
SDC2 SLC7A3 25348397 N/A physical interaction ComPPI
SDC2 SULF2 25348397 N/A physical interaction ComPPI
SDC2 XPC 25348397 N/A physical interaction ComPPI
SDC2 CKAP5 25348397 N/A physical interaction ComPPI
SDC2 OSBPL8 25348397 N/A physical interaction ComPPI
SDC2 ZNF460 25348397 N/A physical interaction ComPPI
SDC2 HEATR6 25348397 N/A physical interaction ComPPI
SDC2 HADHB 25348397 N/A physical interaction ComPPI
SDC2 ZNF92 25348397 N/A physical interaction ComPPI
SDC2 RNF213 25348397 N/A physical interaction ComPPI
SDC2 NCAPH2 25348397 N/A physical interaction ComPPI
SDC2 CAND2 25348397 N/A physical interaction ComPPI
SDC2 LIPG 25348397 N/A physical interaction ComPPI
SDC2 GTF3C1 25348397 N/A physical interaction ComPPI
SDC2 VANGL2 25348397 N/A physical interaction ComPPI
SDC2 PI4KA 25348397 N/A physical interaction ComPPI
SDC2 GTF3C3 25348397 N/A physical interaction ComPPI
SDC2 HADHA 25348397 N/A physical interaction ComPPI
SDC2 TMEM186 25348397 N/A physical interaction ComPPI
SDC2 EXOC3 25348397 N/A physical interaction ComPPI
SDC2 SMC2 25348397 N/A physical interaction ComPPI
SDC2 SDC1 18093920 24234451 25348397 N/A physical interaction,comigration in gel electrophoresis ComPPI,IntAct
SDC2 SDC3 18093920 24234451 25348397 N/A physical interaction,comigration in gel electrophoresis ComPPI,IntAct
SDC2 SDC4 18093920 24234451 25348397 N/A physical interaction,comigration in gel electrophoresis ComPPI,IntAct
SDC2 MYB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
SDC2 RASA1 22471946 24234451 25348397 physical association coimmunoprecipitation ComPPI,IntAct
SDC2 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
SDC2 PYHIN1 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
CSNK2A2 SDC2 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TNFSF13 SDC2 14525934 15846369 27898060 N/A experimental interaction detection HPRD,OmniPath
SDC2 SDC2 18093920 21988832 24234451 physical association two hybrid,tox-r dimerization assay,comigration in gel electrophoresis IntAct
NCBP3 SDC2 24234451 26382858 association pull down IntAct
SRC SDC2 16997272 27898060 inhibition N/A OmniPath
PRKCA SDC2 19901323 27898060 9244383 stimulant N/A OmniPath
PRKCB SDC2 19901323 27898060 9244383 stimulant N/A OmniPath
SDC2 CSF2RA 10734053 27898060 N/A N/A OmniPath
ITGB1 SDC2 10772816 27898060 N/A N/A OmniPath
CXCL8 SDC2 14527339 27898060 N/A N/A OmniPath
FN1 SDC2 10772816 27898060 stimulant N/A OmniPath
PRKCG SDC2 19901323 27898060 9244383 N/A N/A OmniPath
MMP2 SDC2 17623663 27898060 N/A N/A OmniPath
DYRK2 SDC2 27898060 9244383 N/A N/A OmniPath
ITGA5 SDC2 10772816 27898060 N/A N/A OmniPath
SDC2 ITGA5 10772816 27898060 N/A N/A OmniPath
CASK SDC2 12676536 27898060 9660868 N/A N/A OmniPath

Visualization










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