Gene Information gene info

GENE:CNOT8

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CNOT8
FullNmae CCR4-NOT transcription complex subunit 8
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9207
EnsembleID ENSG00000155508
Uniprot Q9UFF9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CNOT8 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CNOT8 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CNOT8 GO:0000175,GO:0000289,GO:0000932,GO:0003723,GO:0004535,GO:0004535,GO:0005515,GO:0005634,GO:0005829,GO:0008284,GO:0030014,GO:0030014,GO:0030015,GO:0035195,GO:0043928,GO:0043928,GO:0046872,GO:0061014

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CNOT8 hsa:9337 path:hsa03018 RNA degradation - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CNOT8 STAT1 23180781 23386060 physical association anti tag coimmunoprecipitation,proximity ligation assay InnateDB
BTG1 CNOT8 23180781 25416956 physical association two hybrid InnateDB
CNOT8 ELAVL1 19322201 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR CNOT8 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 CNOT8 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 CNOT8 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXA1 CNOT8 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 CNOT8 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 CNOT8 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CNOT8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CNOT8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CNOT8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CNOT8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 CNOT8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CNOT8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 CNOT8 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005CC20C CNOT8 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CNOT3 CNOT8 25361965 interaction type N/A PTMCode2
CNOT8 CNOT3 25361965 interaction type N/A PTMCode2
BTG1 CNOT8 25361965 interaction type N/A PTMCode2
CNOT8 BTG1 25361965 interaction type N/A PTMCode2
CNOT6L CNOT8 25361965 interaction type N/A PTMCode2
CNOT8 CNOT6L 25361965 interaction type N/A PTMCode2
CNOT8 BTG2 25361965 interaction type N/A PTMCode2
BTG2 CNOT8 25361965 interaction type N/A PTMCode2
CNOT8 CNOT1 25361965 interaction type N/A PTMCode2
CNOT1 CNOT8 25361965 interaction type N/A PTMCode2
CNOT8 CNOT10 25361965 interaction type N/A PTMCode2
CNOT10 CNOT8 25361965 interaction type N/A PTMCode2
CNOT2 CNOT8 25361965 interaction type N/A PTMCode2
CNOT8 CNOT2 25361965 interaction type N/A PTMCode2
CNOT6 CNOT8 25361965 interaction type N/A PTMCode2
CNOT8 CNOT6 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NANOS2 CNOT8 25348397 N/A physical interaction ComPPI
VCP CNOT8 25348397 N/A physical interaction ComPPI
MMP7 CNOT8 25348397 N/A physical interaction ComPPI
TOB1 CNOT8 25348397 N/A physical interaction ComPPI
GADD45B CNOT8 25348397 N/A physical interaction ComPPI
PRMT1 CNOT8 25348397 N/A physical interaction ComPPI
CAPZA1 CNOT8 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CACYBP CNOT8 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ZFP36 CNOT8 25348397 N/A physical interaction ComPPI
BTG2 CNOT8 11136725 14525934 24234451 25348397 25416956 physical association two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
MARCKS CNOT8 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PUM1 CNOT8 16715093 24234451 25348397 27898060 N/A pull down,physical interaction ComPPI,IntAct,OmniPath
AURKA CNOT8 25348397 N/A physical interaction ComPPI
USP11 CNOT8 25348397 N/A physical interaction ComPPI
ELAVL1 CNOT8 25348397 N/A physical interaction ComPPI
CNOT8 CNOT3 10637334 14525934 16778766 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
CNOT8 CNOT4 10637334 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
CNOT8 CNOT1 10637334 14525934 16778766 17353931 22977175 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
CNOT8 CNOT6 11747467 17452450 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid ComPPI,IntAct
CNOT8 CNOT2 14525934 16778766 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
CNOT8 CNOT10 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT8 MCM7 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT8 TOB2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CNOT8 TNRC6C 21981923 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT8 FCGR3B 25348397 N/A physical interaction ComPPI
CNOT8 CT55 25348397 N/A physical interaction ComPPI
CNOT8 CAPZA2 25348397 N/A physical interaction ComPPI
CNOT8 TNRC6A 21981923 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT8 TNRC6B 21981923 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT8 AGO2 21981923 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT8 UNK 25348397 N/A physical interaction ComPPI
CNOT8 LDHD 25348397 N/A physical interaction ComPPI
CNOT8 RC3H1 25348397 N/A physical interaction ComPPI
CNOT8 CNOT11 25348397 N/A physical interaction ComPPI
CNOT8 RIBC1 25348397 N/A physical interaction ComPPI
CNOT8 GPBP1L1 25348397 N/A physical interaction ComPPI
CNOT8 EZR 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CNOT8 OTUB1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CNOT8 CNOT6L 17452450 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BTG1 CNOT8 11136725 14525934 16189514 21900206 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,HPRD,IntAct
TEX13A CNOT8 25348397 N/A physical interaction ComPPI
CNOT8 STAT1 23386060 27898060 N/A N/A OmniPath

Visualization