Gene Information gene info

  1. Home

GENE：SPAG9

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SPAG9
FullNmae sperm associated antigen 9
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14524
EnsembleID ENSG00000008294
Uniprot O60271

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SPAG9 lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
SPAG9 lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
SPAG9 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SPAG9 GO:0001669,GO:0001933,GO:0005078,GO:0005515,GO:0005737,GO:0005765,GO:0005829,GO:0005829,GO:0008432,GO:0016192,GO:0019894,GO:0030159,GO:0030335,GO:0032418,GO:0034451,GO:0042147,GO:0042802,GO:0043410,GO:0045665,GO:0045666,GO:0048471,GO:0051146,GO:0070062,GO:1903860

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ARF6 SPAG9 19211056 23180781 physical association affinity chromatography technology InnateDB
SPAG9 ZNF239 19490114 23180781 physical association affinity chromatography technology,two hybrid InnateDB
SPAG9 MAP2K4 12391307 23331499 stimulation N/A SignaLink
SPAG9 MAX 12391307 23331499 stimulation N/A SignaLink
SPAG9 MAP3K3 12391307 23331499 stimulation N/A SignaLink
SPAG9 MAPK14 12391307 15767678 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR SPAG9 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 SPAG9 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 SPAG9 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 SPAG9 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 SPAG9 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 SPAG9 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 SPAG9 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 SPAG9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SPAG9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SPAG9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SPAG9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SPAG9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 SPAG9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SPAG9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SPAG9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SPAG9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 SPAG9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 SPAG9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 SPAG9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 SPAG9 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 SPAG9 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000ED600 SPAG9 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS00003380CC SPAG9 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS00000F31F4 SPAG9 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 SPAG9 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS0000070B1D SPAG9 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 SPAG9 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE SPAG9 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000330617 SPAG9 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000000B1C9 SPAG9 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002AB575 SPAG9 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 SPAG9 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 SPAG9 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002F8148 SPAG9 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 SPAG9 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB SPAG9 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004959F4 SPAG9 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003538C1 SPAG9 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000015F70F SPAG9 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001FFA8C SPAG9 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004F24A9 SPAG9 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000008DA94 SPAG9 25416803 26797273 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000003E1A9 SPAG9 25416803 26790956 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CDK2 SPAG9 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
VASN SPAG9 25348397 N/A physical interaction ComPPI
CBX8 SPAG9 21282530 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ZBED1 SPAG9 25348397 N/A physical interaction ComPPI
TP53BP1 SPAG9 25348397 N/A physical interaction ComPPI
MCM6 SPAG9 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MCM2 SPAG9 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAP1LC3B SPAG9 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PNRC2 SPAG9 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ABRAXAS2 SPAG9 25348397 N/A physical interaction ComPPI
CD2AP SPAG9 25348397 N/A physical interaction ComPPI
MAPK8 SPAG9 12391307 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MAPK14 SPAG9 12391307 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
NTRK1 SPAG9 25348397 N/A physical interaction ComPPI
MAP2K4 SPAG9 12391307 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PLK1 SPAG9 19596235 24234451 25348397 27173435 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
MYC SPAG9 12391307 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
MAPK8IP3 SPAG9 25348397 N/A physical interaction ComPPI
NDRG1 SPAG9 25348397 N/A physical interaction ComPPI
TPM3 SPAG9 25348397 N/A physical interaction ComPPI
EXOC4 SPAG9 24234451 25244576 25348397 27898060 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,fluorescence microscopy ComPPI,IntAct,OmniPath
RRM2 SPAG9 25348397 N/A physical interaction ComPPI
RRM2B SPAG9 25348397 N/A physical interaction ComPPI
HUWE1 SPAG9 25348397 N/A physical interaction ComPPI
ARF6 SPAG9 19644450 24234451 25348397 N/A cosedimentation in solution,surface plasmon resonance,x-ray crystallography ComPPI,IntAct
SMC1A SPAG9 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
KLC1 SPAG9 14525934 15987681 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
SOX4 SPAG9 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MED9 SPAG9 25348397 N/A physical interaction ComPPI
SYP SPAG9 25348397 N/A physical interaction ComPPI
BCR SPAG9 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SCARB2 SPAG9 25348397 N/A physical interaction ComPPI
WEE1 SPAG9 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NOLC1 SPAG9 25348397 N/A physical interaction ComPPI
SPAG9 MAP3K3 12391307 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SPAG9 NFKB1 14525934 14743216 24234451 25348397 25609649 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
SPAG9 MAX 12391307 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SPAG9 EIF4A2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SPAG9 SIRT7 25348397 N/A physical interaction ComPPI
SPAG9 MAP2K3 25348397 N/A physical interaction ComPPI
SPAG9 NENF 25348397 N/A physical interaction ComPPI
SPAG9 BRCC3 25348397 N/A physical interaction ComPPI
SPAG9 MTA2 25348397 N/A physical interaction ComPPI
SPAG9 LARP7 25348397 N/A physical interaction ComPPI
SPAG9 RABEP2 25348397 N/A physical interaction ComPPI
SPAG9 TXNDC9 25348397 N/A physical interaction ComPPI
SPAG9 ABL1 25348397 N/A physical interaction ComPPI
SPAG9 MREG 25348397 N/A physical interaction ComPPI
SPAG9 FAM219B 25348397 N/A physical interaction ComPPI
SPAG9 MED4 25348397 N/A physical interaction ComPPI
SPAG9 EYA1 25348397 N/A physical interaction ComPPI
SPAG9 PPEF2 25348397 N/A physical interaction ComPPI
SPAG9 PPM1D 25348397 N/A physical interaction ComPPI
SPAG9 PPM1K 25348397 N/A physical interaction ComPPI
SPAG9 TPTE 25348397 N/A physical interaction ComPPI
SPAG9 SMCO1 25348397 N/A physical interaction ComPPI
SPAG9 BMERB1 25348397 N/A physical interaction ComPPI
SPAG9 ARFGAP1 25348397 N/A physical interaction ComPPI
SPAG9 RCCD1 25348397 N/A physical interaction ComPPI
SPAG9 SLC30A4 25348397 N/A physical interaction ComPPI
SPAG9 PODXL 25348397 N/A physical interaction ComPPI
SPAG9 FAM174A 25348397 N/A physical interaction ComPPI
SPAG9 ACOT12 25348397 N/A physical interaction ComPPI
SPAG9 CACNG5 25348397 N/A physical interaction ComPPI
SPAG9 TPM1 25348397 N/A physical interaction ComPPI
SPAG9 KIF16B 25348397 N/A physical interaction ComPPI
SPAG9 TMEM44 25348397 N/A physical interaction ComPPI
SPAG9 KLHL40 25348397 N/A physical interaction ComPPI
SPAG9 ZFPL1 25348397 N/A physical interaction ComPPI
SPAG9 BIRC7 25348397 N/A physical interaction ComPPI
SPAG9 MND1 25348397 N/A physical interaction ComPPI
SPAG9 SPN 25348397 N/A physical interaction ComPPI
SPAG9 USP15 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SPAG9 MCM4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SPAG9 EPS15L1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SPAG9 IVNS1ABP 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SPAG9 GTF3C4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SPAG9 GAPVD1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SPAG9 ANK3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SPAG9 SMC3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SPAG9 SBNO1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SPAG9 CDK11B 25348397 N/A physical interaction ComPPI
SPAG9 CDK11A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SPAG9 PPP4R2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SPAG9 HSF1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SPAG9 RELCH 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SPAG9 MCM7 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SPAG9 ATG2B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SPAG9 PPP4R3A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SPAG9 GTF3C2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SPAG9 TRIM25 25348397 N/A physical interaction ComPPI
SPAG9 BRCA1 25348397 N/A physical interaction ComPPI
SPAG9 ARF1 19644450 24234451 25348397 N/A surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
SPAG9 GATA3 24234451 25348397 26028330 association anti tag coimmunoprecipitation ComPPI,IntAct
COMTD1 SPAG9 25348397 N/A physical interaction ComPPI
SPAG9 SPAG9 12391307 14525934 19644450 24234451 N/A cosedimentation in solution,experimental interaction detection HPRD,IntAct
SPAG9 PIKFYVE 19056739 27898060 N/A N/A OmniPath
SPAG9 MAP2K4 12391307 27898060 stimulant N/A OmniPath
SPAG9 MAX 12391307 27898060 stimulant N/A OmniPath
SPAG9 MAPK14 12391307 1239131 15767678 17074887 27898060 stimulant N/A OmniPath
SPAG9 MAPK11 17074887 27898060 stimulant N/A OmniPath
SPAG9 MAP3K3 12391307 27898060 stimulant N/A OmniPath
CDON SPAG9 17074887 18678706 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009BAB41 SPAG9 27087310 direct interaction,inhibition N/A NPInter

Visualization










  Return