Gene Information gene info

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GENE：TFPI

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TFPI
FullNmae tissue factor pathway inhibitor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11760
EnsembleID ENSG00000003436
Uniprot P10646

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TFPI autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TFPI GO:0004866,GO:0004867,GO:0005576,GO:0005615,GO:0005615,GO:0005783,GO:0005886,GO:0005901,GO:0007596,GO:0009986,GO:0009986,GO:0030195,GO:0071383,GO:0098552

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TFPI hsa:7035 path:hsa04610 Complement and coagulation cascades - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PITX3 TFPI 22278372 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR TFPI 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 TFPI 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 TFPI 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 TFPI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TFPI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TFPI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TFPI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 TFPI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TFPI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TFPI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 TFPI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 TFPI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 TFPI 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 TFPI 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000338542 TFPI 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000028BB8 TFPI 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS0000122ED0 TFPI 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00002367FA TFPI 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00003EB4CF TFPI 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001F373E TFPI 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000027F5F3 TFPI 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000045ED38 TFPI 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 TFPI 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000061E50F TFPI 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDA4 TFPI 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004D84DB TFPI 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 TFPI 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005E1A16 TFPI 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000122F23 TFPI 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 TFPI 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000105D19 TFPI 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000568FF8 TFPI 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075D814 TFPI 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 TFPI 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004F859B TFPI 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005485E8 TFPI 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000015A0D9 TFPI 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000331800 TFPI 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC TFPI 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002B0920 TFPI 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000003FD55 TFPI 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004AC389 TFPI 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000016D2D4 TFPI 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F TFPI 25416803 26999003 mrna cleavage,inhibition experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000535FDD TFPI 25416803 26999003 mrna cleavage,inhibition experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 TFPI 22135298 phosphorylation N/A PhosphoSite
TFPI THBS1 25361965 interaction type N/A PTMCode2
THBS1 TFPI 25361965 interaction type N/A PTMCode2
TFPI F10 25361965 interaction type N/A PTMCode2
F10 TFPI 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
BCAS2 TFPI 25348397 N/A physical interaction ComPPI
SAP18 TFPI 25348397 N/A physical interaction ComPPI
MMP7 TFPI 10859319 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SF3B1 TFPI 25348397 N/A physical interaction ComPPI
ELANE TFPI 10859319 12117418 14525934 1558967 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
F10 TFPI 12787023 14525934 25348397 3422166 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
THBS1 TFPI 10922378 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
MMP12 TFPI 10859319 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SON TFPI 25348397 N/A physical interaction ComPPI
SRSF11 TFPI 25348397 N/A physical interaction ComPPI
ELAVL1 TFPI 25348397 N/A physical interaction ComPPI
KCNIP4 TFPI 25348397 N/A physical interaction ComPPI
SRSF7 TFPI 25348397 N/A physical interaction ComPPI
MMP9 TFPI 10859319 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PRSS3 TFPI 14525934 25348397 27898060 7498454 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
MMP8 TFPI 12117418 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TFPI APP 25348397 N/A physical interaction ComPPI
TFPI SMU1 25348397 N/A physical interaction ComPPI
MMP1 TFPI 10859319 14525934 N/A experimental interaction detection HPRD
CSNK2A1 TFPI 2122883 27898060 N/A N/A OmniPath
TFPI VLDLR 11278667 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B4B61 TFPI 27087310 direct interaction,inhibition N/A NPInter

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