GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
TFPI |
FullNmae |
tissue factor pathway inhibitor |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:11760 |
EnsembleID |
ENSG00000003436 |
Uniprot |
P10646 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
TFPI |
autosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
TFPI |
GO:0004866,GO:0004867,GO:0005576,GO:0005615,GO:0005615,GO:0005783,GO:0005886,GO:0005901,GO:0007596,GO:0009986,GO:0009986,GO:0030195,GO:0071383,GO:0098552 |
KEGG Annotation:
GeneSymbol |
GeneID |
Pathway |
Pathway Name |
TFPI |
hsa:7035 |
path:hsa04610 |
Complement and coagulation cascades - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
PITX3 |
TFPI |
22278372
23180781
|
physical association |
anti tag coimmunoprecipitation |
InnateDB |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
AR |
TFPI |
20610535
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
GATA2 |
TFPI |
18971253
19941826
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
FOXP3 |
TFPI |
20554955
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
SMARCA4 |
TFPI |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CEBPA |
TFPI |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
TFPI |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXA1 |
TFPI |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXP1 |
TFPI |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOS |
TFPI |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
HNF4A |
TFPI |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
RUNX1 |
TFPI |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
SPI1 |
TFPI |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TAL1 |
TFPI |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS0000237AF9 |
TFPI |
18185580
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
URS0000338542 |
TFPI |
18668040
25416803
|
mrna cleavage,inhibition |
experimental interaction detection |
TarBase |
URS0000028BB8 |
TFPI |
17612493
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
URS0000122ED0 |
TFPI |
19088304
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
URS00002367FA |
TFPI |
22100165
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00003EB4CF |
TFPI |
22100165
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00001F373E |
TFPI |
22100165
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000027F5F3 |
TFPI |
22100165
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000045ED38 |
TFPI |
22100165
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000221168 |
TFPI |
22100165
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000061E50F |
TFPI |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000075BDA4 |
TFPI |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00004D84DB |
TFPI |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000007F792 |
TFPI |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00005E1A16 |
TFPI |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000122F23 |
TFPI |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000008A99 |
TFPI |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000105D19 |
TFPI |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000568FF8 |
TFPI |
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000075D814 |
TFPI |
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000075CC78 |
TFPI |
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00004F859B |
TFPI |
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00005485E8 |
TFPI |
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000015A0D9 |
TFPI |
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000331800 |
TFPI |
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00001012BC |
TFPI |
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00002B0920 |
TFPI |
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000003FD55 |
TFPI |
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00004AC389 |
TFPI |
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000016D2D4 |
TFPI |
23446348
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00001B341F |
TFPI |
25416803
26999003
|
mrna cleavage,inhibition |
experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay |
TarBase |
URS0000535FDD |
TFPI |
25416803
26999003
|
mrna cleavage,inhibition |
experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
CSNK2A1 |
TFPI |
22135298
|
phosphorylation |
N/A |
PhosphoSite |
TFPI |
THBS1 |
25361965
|
interaction type |
N/A |
PTMCode2 |
THBS1 |
TFPI |
25361965
|
interaction type |
N/A |
PTMCode2 |
TFPI |
F10 |
25361965
|
interaction type |
N/A |
PTMCode2 |
F10 |
TFPI |
25361965
|
interaction type |
N/A |
PTMCode2 |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
BCAS2 |
TFPI |
25348397
|
N/A |
physical interaction |
ComPPI |
SAP18 |
TFPI |
25348397
|
N/A |
physical interaction |
ComPPI |
MMP7 |
TFPI |
10859319
14525934
25348397
|
N/A |
experimental interaction detection,in vitro |
ComPPI,HPRD |
SF3B1 |
TFPI |
25348397
|
N/A |
physical interaction |
ComPPI |
ELANE |
TFPI |
10859319
12117418
14525934
1558967
25348397
27898060
|
N/A |
experimental interaction detection,in vitro |
ComPPI,HPRD,OmniPath |
F10 |
TFPI |
12787023
14525934
25348397
3422166
|
N/A |
experimental interaction detection,physical interaction,in vitro |
ComPPI,HPRD |
THBS1 |
TFPI |
10922378
14525934
25348397
27898060
|
N/A |
experimental interaction detection,physical interaction,in vitro |
ComPPI,HPRD,OmniPath |
MMP12 |
TFPI |
10859319
14525934
25348397
|
N/A |
experimental interaction detection,in vitro |
ComPPI,HPRD |
SON |
TFPI |
25348397
|
N/A |
physical interaction |
ComPPI |
SRSF11 |
TFPI |
25348397
|
N/A |
physical interaction |
ComPPI |
ELAVL1 |
TFPI |
25348397
|
N/A |
physical interaction |
ComPPI |
KCNIP4 |
TFPI |
25348397
|
N/A |
physical interaction |
ComPPI |
SRSF7 |
TFPI |
25348397
|
N/A |
physical interaction |
ComPPI |
MMP9 |
TFPI |
10859319
14525934
25348397
|
N/A |
experimental interaction detection,in vitro |
ComPPI,HPRD |
PRSS3 |
TFPI |
14525934
25348397
27898060
7498454
|
N/A |
experimental interaction detection,physical interaction,in vitro |
ComPPI,HPRD,OmniPath |
MMP8 |
TFPI |
12117418
14525934
25348397
|
N/A |
experimental interaction detection,in vitro |
ComPPI,HPRD |
TFPI |
APP |
25348397
|
N/A |
physical interaction |
ComPPI |
TFPI |
SMU1 |
25348397
|
N/A |
physical interaction |
ComPPI |
MMP1 |
TFPI |
10859319
14525934
|
N/A |
experimental interaction detection |
HPRD |
CSNK2A1 |
TFPI |
2122883
27898060
|
N/A |
N/A |
OmniPath |
TFPI |
VLDLR |
11278667
27898060
|
stimulant |
N/A |
OmniPath |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS00009B4B61 |
TFPI |
27087310
|
direct interaction,inhibition |
N/A |
NPInter |
Visualization